Ikawa, Masahito

Profile

Dr. Ikawa received his Ph.D. from Osaka University in 1997. After working as JSPS postdoctoral fellow and a Research Associate at Genome Information Research Center in Osaka University, he spent 2 years at The Salk Institute in the USA as a Research Associate. After returning to Osaka University in 2002, he became an Associate Professor in 2004 and was appointed to the current position in 2012. He was awarded JSPS Prize in 2013. His lifework is to study mammalian reproductive systems using genetically engineered mice.

Publication

  • 1) ARMC12 regulates spatiotemporal mitochondrial dynamics during spermiogenesis and is required for male fertility. Shimada K., PNAS. 2021 Feb 9;118(6):e2018355118.
  • 2)Bi-allelic DNAH8 Variants Lead to Multiple Morphological Abnormalities of the Sperm Flagella and Primary Male Infertility. Liu C., et al. Am J Hum Genet. 2020 Aug 6;107(2):330-341.
  • 3) NELL2-mediated lumicrine signaling through OVCH2 is required for male fertility. Kiyozumi D., et al. Science. 2020 Jun 5;368(6495):1132-1135.
  • 4) Sperm proteins SOF1, TMEM95, and SPACA6 are required for sperm-oocyte fusion in mice. Noda T., et al. PNAS. 2020 May 26;117(21):11493-11502.
  • 5) Spermatozoa lacking Fertilization Influencing Membrane Protein (FIMP) fail to fuse with oocytes in mice. Fujihara Y., et al. PNAS. 2020 Apr 28;117(17):9393-9400.
  • 6) Sperm calcineurin inhibition prevents mouse fertility with implications for male contraceptive. Miyata H., Science. 2015 Oct 23;350(6259):442-5.

Lab

AKIRA, Shizuo

Division of Host Defense

Department of Host Defense

Aoshi, Taiki

Endowed Chair

Department of Cellular Immunology

Arase, Hisashi

Division of Host Defense

Department of Immunochemistry

Ebina, Hirotaka

BIKEN Innovative Vaccine Research Alliance Laboratories

Virus Vaccine Group

Hara, Eiji

Division of Cellular and Molecular Biology

Department of Molecular Microbiology

Horiguchi, Yasuhiko

Division of Infectious Disease

Department of Molecular Bacteriology

Horii, Toshihiro

Endowed Chair

Department of Malaria Vaccine Development

Iida, Tetsuya

Research Center for Infectious Disease Control

Department of Bacterial Infections

Ishitani, Tohru

Division of Cellular and Molecular Biology

Department of Homeostatic Regulation

Iwanaga, Shiroh

Research Center for Infectious Disease Control

Department of Molecular Protozoology

Iwasaki, Masaharu

International Research Center for Infectious Diseases

Laboratory of Emerging Viral Diseases

Kinoshita, Taroh

Endowed Chair

Kobayashi, Takeshi

Research Center for Infectious Disease Control

Department of Virology

Maeda, Yusuke

International Research Center for Infectious Diseases

Laboratory of Viral Dynamism Research

Matsuura, Yoshiharu

Research Center for Infectious Disease Control

Laboratory of Virus Control

Miki, Hiroaki

Division of Cellular and Molecular Biology

Department of Cellular Regulation

Mimuro, Hitomi

Division of Infectious Disease

Department of Infection Microbiology

Murakami, Yoshiko

Endowed Chair

Nakamura, Shota

International Research Center for Infectious Diseases

Laboratory of Pathogen Detection and Identification

Okada, Masato

Division of Cellular and Molecular Biology

Department of Oncogene Research

Okamoto, Toru

Division of Infectious Disease

Institute for Advanced Co-Creation Studies

Shioda, Tatsuo

Division of Infectious Disease

Department of Viral Infections

Standley, Daron

Genome Information Research Center

Department of Genome Informatics

Suzuki, Kazuhiro

Division of Host Defense

Department of Immune Response Dynamics

Takakura, Nobuyuki

Division of Cellular and Molecular Biology

Department of Signal Transduction

Watanabe, Tokiko

Division of Infectious Disease

Department of Molecular Virology

Yamamoto, Masahiro

Division of Infectious Disease

Department of Immunoparasitology

Yamasaki, Sho

Division of Host Defense

Department of Molecular Immunology

Yoshioka, Yasuo

BIKEN Innovative Vaccine Research Alliance Laboratories

Vaccine Creation Group