Research Activities

Regulation of GPI structural remodeling by protein N-glycosylation (Kinoshita Lab, in J. Cell Biol.)

Most proteins receive various modifications after their synthesis, called post-translational modi...

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Cellular senescence-associated factors in MDSCs promote tumour growth (Hara lab in Nat. Commun)

Cellular senescence is a state of irreversible cell cycle arrest and induced by oncogenic stress....

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Discovery of key molecules involved in severe malaria (Arase Lab in Nature)

Drs. Saito, Hirayasu, Arase and others have revealed a novel molecular mechanism that P. falcipar...

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SPP is an ideal target for therapeutics against not only chronic hepatitis C but also protozoiasis (Matsuura Lab, in PNAS)

Hepatitis C virus (HCV) is a major causative agent of chronic liver diseases including steatosis,...

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Crystal structure of Ragulator determined (Okada Lab, in Nat.Commun)

The mechanistic target of rapamycin complex 1 (mTORC1) plays a central role in regulating cell gr...

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Host-derived apolipoproteins play comparable roles with viral secretory proteins Erns and NS1 in the infectious particle formation of Flaviviridae (Matsuura Lab, in PLoS Pathogens)

Amphipathic α-helices of exchangeable apolipoproteins have shown to play crucial roles in t...

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Identification of the molecule that regulates sperm motility (Ikawa Lab, in PNAS)

Sperm motility is essential for sperm to traverse the female reproductive tract to deliver half o...

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Essential role for GABARAP autophagy proteins in interferon-inducible GTPase-mediated host defense (Yamamoto Lab, in Nat Immunolgy)

Although functions of autophagy-related (Atg) proteins in canonical autophagy are well understood...

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Small extracellular vesicles secreted from senescent cells promote cancer cell proliferation through EphA2 (Hara Lab, in Nature Commun)

Cellular senescence, a state of irreversible cell cycle arrest, prevents the proliferation of cel...

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Characterization of miR-122-independent propagation of HCV (from Matsuura Lab, in PLoS Pathogens)

A liver-specific microRNA, miR-122, is one of the key determinants of hepatitis C virus (HCV) hep...

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Exosomes maintain cellular homeostasis by excreting harmful DNA from cells (Hara Lab in Nat. Commun.)

Emerging evidence has indicated that exosomes play important roles in intercellular communication...

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A Glycolipid acts as an immunostimulatory factor upon cell damage (Press release from Kyushu Univ.)

The Article from Yamasaki Lab published in PNAS. 

Check detail in Kyushu University website...

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Research achievements from Sato Lab published in Nat Commun.

M cells are specialized antigen-sampling cells that take up intestinal luminal antigens. A resear...

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PNAS USA, 2017 Jan 30.2017/01/30

Rotaviruses (RVs) are highly important pathogens that cause severe diarrhea among infants and you...

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