Research Activities
Regulation of GPI structural remodeling by protein N-glycosylation (Kinoshita Lab, in J. Cell Biol.)
Most proteins receive various modifications after their synthesis, called post-translational modi...
Cellular senescence-associated factors in MDSCs promote tumour growth (Hara lab in Nat. Commun)
Cellular senescence is a state of irreversible cell cycle arrest and induced by oncogenic stress....
Discovery of key molecules involved in severe malaria (Arase Lab in Nature)
Drs. Saito, Hirayasu, Arase and others have revealed a novel molecular mechanism that P. falcipar...
SPP is an ideal target for therapeutics against not only chronic hepatitis C but also protozoiasis (Matsuura Lab, in PNAS)
Hepatitis C virus (HCV) is a major causative agent of chronic liver diseases including steatosis,...
Crystal structure of Ragulator determined (Okada Lab, in Nat.Commun)
The mechanistic target of rapamycin complex 1 (mTORC1) plays a central role in regulating cell gr...
Host-derived apolipoproteins play comparable roles with viral secretory proteins Erns and NS1 in the infectious particle formation of Flaviviridae (Matsuura Lab, in PLoS Pathogens)
Amphipathic α-helices of exchangeable apolipoproteins have shown to play crucial roles in t...
Identification of the molecule that regulates sperm motility (Ikawa Lab, in PNAS)
Sperm motility is essential for sperm to traverse the female reproductive tract to deliver half o...
Essential role for GABARAP autophagy proteins in interferon-inducible GTPase-mediated host defense (Yamamoto Lab, in Nat Immunolgy)
Although functions of autophagy-related (Atg) proteins in canonical autophagy are well understood...
Small extracellular vesicles secreted from senescent cells promote cancer cell proliferation through EphA2 (Hara Lab, in Nature Commun)
Cellular senescence, a state of irreversible cell cycle arrest, prevents the proliferation of cel...
Characterization of miR-122-independent propagation of HCV (from Matsuura Lab, in PLoS Pathogens)
A liver-specific microRNA, miR-122, is one of the key determinants of hepatitis C virus (HCV) hep...
Exosomes maintain cellular homeostasis by excreting harmful DNA from cells (Hara Lab in Nat. Commun.)
Emerging evidence has indicated that exosomes play important roles in intercellular communication...
A Glycolipid acts as an immunostimulatory factor upon cell damage (Press release from Kyushu Univ.)
The Article from Yamasaki Lab published in PNAS.
Check detail in Kyushu University website...
Research achievements from Sato Lab published in Nat Commun.
M cells are specialized antigen-sampling cells that take up intestinal luminal antigens. A resear...
PNAS USA, 2017 Jan 30.2017/01/30
Rotaviruses (RVs) are highly important pathogens that cause severe diarrhea among infants and you...
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