Hara, Eiji

Profile

Dr. Hara received his Ph.D. from Tokyo University of Science in 1993. After working at Imperial Cancer Research Fund Laboratories, U.K. (Postdoctoral Fellow), Cancer Research UK-Paterson Institute, U.K. (Group Leader) and the Institute for Genome Research, University of Tokushima (Professor), he was appointed Division Chief in the Cancer Institute, Japanese Foundation for Cancer Research in 2008. He took his current position at RIMD from 2015.

Publication

  • (1)Downregulation of cytoplasmic DNases is implicated in cytoplasmic DNA accumulation and SASP in senescent cells. Takahashi A., et al., Nat Commun. (2018) 9(1):1249 
  • (2) Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome. Yoshimoto S., et al., Nature (2013) 499:97-101. 
  • (3) DNA damage signaling triggers degradation of histone methyltransferases through APC/CCdh1 in senescent cells. Takahashi A., et al., Molecular Cell (2012) 45:123-31.
  • (4) Real-time in vivo imaging of p16Ink4a reveals cross-talk with p53. Yamakoshi K., et al., Journal of Cell Biology (2009) 186:393-407.
  • (5) Mitogenic signalling and the p16INK4a- Rb pathway cooperate to enforce irreversible cellular senescence. Takahashi A., et al., Nature Cell Biology (2006) 8:1291-7.
  • (6) Opposing effects of Ets and Id proteins on p16INK4a expression during cellular senescence. Ohtani N., et al., Nature (2001) 409:1067-70.

Lab

AKIRA, Shizuo

Division of Host Defense

Department of Host Defense

Aoshi, Taiki

Endowed Chair

Department of Cellular Immunology

Arase, Hisashi

Division of Host Defense

Department of Immunochemistry

Ebina, Hirotaka

BIKEN Innovative Vaccine Research Alliance Laboratories

Virus Vaccine Group

Hamada, Shigeyuki

Research Collaboration Center for Infectious Diseases

Section of Bacterial Drug Resistance Research

Horiguchi, Yasuhiko

Division of Infectious Disease

Department of Molecular Bacteriology

Horii, Toshihiro

Endowed Chair

Department of Malaria Vaccine Development

Iida, Tetsuya

Research Center for Infectious Disease Control

Department of Bacterial Infections

Ikawa, Masahito

Genome Information Research Center

Department of Experimental Genome Research

Ishitani, Tohru

Division of Cellular and Molecular Biology

Department of Homeostatic regulation

Iwanaga, Shiroh

Research Center for Infectious Disease Control

Department of Molecular Protozoology

Iwasaki, Masaharu

International Research Center for Infectious Diseases

Laboratory of Emerging Viral Diseases

KAMITANI, Wataru

International Research Center for Infectious Diseases

Laboratory of Clinical Research on Infectious Diseases

Kinoshita, Taroh

Endowed Chair

Yabumoto Department of Intractable Disease Research

Kobayashi, Takeshi

Research Center for Infectious Disease Control

Department of Virology

Maeda, Yusuke

International Research Center for Infectious Diseases

Laboratory of Viral Dynamism Research

Matsuura, Yoshiharu

Division of Infectious Disease

Department of Molecular Virology

Miki, Hiroaki

Division of Cellular and Molecular Biology

Department of Cellular Regulation

Mimuro, Hitomi

Division of Infectious Disease

Department of Infection Microbiology

Murakami, Yoshiko

Endowed Chair

Yabumoto Department of Intractable Disease Research

Nakamura, Shota

International Research Center for Infectious Diseases

Laboratory of Pathogen Detection and Identification

Okada, Masato

Division of Cellular and Molecular Biology

Department of Oncogene Research

Okamoto, Toru

Division of Infectious Disease

Institute for Advanced Co-Creation Studies

Shioda, Tatsuo

Division of Infectious Disease

Department of Viral Infections

Standley, Daron

Genome Information Research Center

Department of Genome Informatics

Suzuki, Kazuhiro

Division of Host Defense

Department of Immune Response Dynamics

Takakura, Nobuyuki

Division of Cellular and Molecular Biology

Department of Signal Transduction

Tatsumi, Masashi

Research Collaboration Center for Infectious Diseases

Section of Viral Infections

Watanabe, Tokiko

Division of Infectious Disease

Yamamoto, Masahiro

Division of Infectious Disease

Department of Immunoparasitology

Yamasaki, Sho

Division of Host Defense

Department of Molecular Immunology

Yoshioka, Yasuo

BIKEN Innovative Vaccine Research Alliance Laboratories

Vaccine Creation Group