石谷太

Profile

2002年名古屋大学大学院理学研究科博士課程修了。日本学術振興会特別研究員、科技団研究員などを経て、2006-17年九州大学生体防御医学研究所独立助教授/独立准教授。2017年群馬大学生体調節研究所教授。2019年より現職。2009年文部科学大臣表彰若手研究者賞受賞。2014年日本生化学会柿内三郎記念奨励研究賞受賞。2020年長瀬研究振興賞受賞。

Publication

(1) Sex-dependent regulation of vertebrate somatic growth and aging by germ cells. Abe et a., Science Advances (2024) 10:eadi1621
(2) Determining zebrafish dorsal organizer size by a negative feedback loop between canonical/non-canonical Wnts and Tlr4/NFκB. Zou J, et al., Nature Commun. (2023) 14(1):7194.
(3) Zebrafish imaging reveals additional TP53 mutation switching oncogene-induced senescence from suppressor to driver in primary tumorigenesis. Haraoka Y., et al., Nature Commun. (2022) 13:1417
(4) Cell competition corrects noisy Wnt/β-catenin morphogen gradients to achieve robust patterning in the zebrafish embryo. Akieda Y., et al., Nature Commun. (2019)10: 4710
(5) Hipk2 and PP1c cooperate to maintain Dvl protein levels required for Wnt signal transduction. Shimizu N., et al., Cell Reports (2014) 8(5) 1391-1404
(6) NLK positively regulates Wnt/β-catenin signalling by phosphorylating LEF1 in neural progenitor cells. Ota S., et al., EMBO Journal (2012) 31:1904-15
(7) Nemo-like kinase suppresses Notch signalling by interfering with formation of the Notch active transcriptional complex. Ishitani T., et al., Nat. Cell Biol. (2010) 12:278-85
(8) Nrarp functions to modulate neural-crest-cell differentiation by regulating LEF1 protein stability. Ishitani T., et al., Nat. Cell Biol. (2005) 7:1106-12
(9) The TAK1-NLK-MAPK-related pathway antagonizes signalling between beta-catenin and transcription factor TCF. Ishitani T., et al., Nature (1999) 399:798-802

研究室紹介