Kobayashi, Takeshi

Profile
Dr. Kobayashi received his Ph.D. from Osaka University in 2000. He became a Research associate at RIMD in the same year. He spent for five years as a postdoctoral fellow in Vanderbilt University, USA before returning to Japan to work at the Institute for Virus Research in Kyoto University. He was appointed SA Associate Professor of RIMD in 2012. He is in his current position from 2020.
Publication
- (1) Recovery of infectious recombinant human norovirus using zebrafish embryos. Kotaki T., et al., PNAS. (2025)122:e2526726122.
- (2) Single-round infectious rotaviruses with deletions of VP7 or VP4 genes, based on SA11 and WC3 strain backbones, and their potential use as viral vectors. Kotaki T., et al., PLoS Pathog. (2025)21:e1013484.
- (3) A rotavirus VP4 or VP7 monoreassortant panel identifies genotypes that are less susceptible to neutralization by systemic antibodies induced by vaccination or natural infection. Kotaki T., et al., mBio. (2025)16:e0089725.
- (4) Establishment of reverse genetics systems for Colorado tick fever virus. Minami S., et al., PLoS Pathog. (2025)21:e1012921.
- (5) The nonstructural p17 protein of a fusogenic bat-borne reovirus regulates viral replication in virus species- and host-specific manners. Nouda R., et al., PLoS Pathog. (2022)18:e1010553.
- (6) Development of an entirely plasmid-based reverse genetics system for 12-segmented double-stranded RNA viruses. Nouda R., et al., PNAS. (2021)118:e2105334118.
- (7) Cell-cell fusion induced by reovirus FAST proteins enhances replication and pathogenicity of non-enveloped dsRNA viruses. Kanai Y., et al., PLoS Pathog. (2019)15:e1007675.
- (8) Entirely plasmid-based reverse genetics system for rotaviruses. Kanai Y., et al., PNAS. (2017)114:2349-2354.
- (9) Reverse Genetics for Fusogenic Bat-Borne Orthoreovirus Associated with Acute Respiratory Tract Infections in Humans: Role of Outer Capsid Protein sigmaC in Viral Replication and Pathogenesis. Kawagishi T., et al., PLoS Pathog. (2016)12:e1005455.

Abe, Ryuichiro
International Research Center for Infectious Diseases
Laboratory of Bacterial Pathogenesis

Akira, Shizuo
Division of Host Defense
Department of Host Defense
Arase, Hisashi
Division of Host Defense
Department of Immunochemistry

Ebina, Hirotaka
BIKEN Innovative Vaccine Research Alliance Laboratories
Virus Vaccine Group

Fujimoto, Kosuke
Division of Infectious Disease
Department of Microbial Regulation

Hara, Eiji
Division of Cellular and Molecular Biology
Department of Molecular Biology

Horii, Toshihiro
Research Center for Infectious Disease Control
Laboratory of Malaria Vaccine Development

Iida, Tetsuya
Research Center for Infectious Disease Control
Department of Bacterial Infections

Ikawa, Masahito
Bioinformatics Center
Department of Experimental Genome Research

Ishitani, Tohru
Division of Cellular and Molecular Biology
Department of Homeostatic Regulation

Iwanaga, Shiroh
Research Center for Infectious Disease Control
Department of Molecular Protozoology

Iwasaki, Masaharu
International Research Center for Infectious Diseases
Laboratory of Emerging Viral Diseases

Kenji Kamimoto
Division of Cellular and Molecular Biology
Department of Systems Biomedical Science

Kotani, Ai
Division of Cellular and Molecular Biology
Department of Regulation of Infectious Cancer

Matsuura, Yoshiharu
Research Center for Infectious Disease Control
Laboratory of Virus Control

Murakami, Yoshiko
Division of Host Defense
Laboratory of Immunoglycobiology

Nakamura, Shota
Bioinformatics Center
Department of Infection Metagenomics

Nakatani, Yoichiro
Bioinformatics Center
Department of Biological Informatics Laboratory of Medical and Evolutionary Genomics

Standley, Daron
Bioinformatics Center
Department of Genome Informatics

Suzuki, Kazuhiro
Division of Host Defense
Department of Immune Response Dynamics

Takakura, Nobuyuki
Division of Cellular and Molecular Biology
Department of Signal Transduction

Tsukamoto, Kentaro
International Research Center for Infectious Diseases
Laboratory of Bacterial Zoonoses

Watanabe, Tokiko
Division of Infectious Disease
Department of Molecular Virology

Yamamoto, Masahiro
Division of Infectious Disease
Department of Immunoparasitology

Yamasaki, Sho
Division of Host Defense
Department of Molecular Immunology

Yamasaki, Shotaro
Bioinformatics Center
Department of Biological Informatics Laboratory of RNA Informatics

Yoshioka, Yasuo
BIKEN Innovative Vaccine Research Alliance Laboratories
Vaccine Creation Group
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