Kobayashi, Takeshi

Profile

Dr. Kobayashi received his Ph.D. from Osaka University in 2000. He became a Research associate at RIMD in the same year. He spent for five years as a postdoctoral fellow in Vanderbilt University, USA before returning to Japan to work at the Institute for Virus Research in Kyoto University. He was appointed SA Associate Professor of RIMD in 2012. He is in his current position from 2020.

 

Publication

  • (1) Recovery of infectious recombinant human norovirus using zebrafish embryos. Kotaki T., et al., PNAS. (2025)122:e2526726122.
  • (2) Single-round infectious rotaviruses with deletions of VP7 or VP4 genes, based on SA11 and WC3 strain backbones, and their potential use as viral vectors. Kotaki T., et al., PLoS Pathog. (2025)21:e1013484.
  • (3) A rotavirus VP4 or VP7 monoreassortant panel identifies genotypes that are less susceptible to neutralization by systemic antibodies induced by vaccination or natural infection. Kotaki T., et al., mBio. (2025)16:e0089725.
  • (4) Establishment of reverse genetics systems for Colorado tick fever virus. Minami S., et al., PLoS Pathog. (2025)21:e1012921.
  • (5) The nonstructural p17 protein of a fusogenic bat-borne reovirus regulates viral replication in virus species- and host-specific manners. Nouda R., et al., PLoS Pathog. (2022)18:e1010553.
  • (6) Development of an entirely plasmid-based reverse genetics system for 12-segmented double-stranded RNA viruses. Nouda R., et al., PNAS. (2021)118:e2105334118.
  • (7) Cell-cell fusion induced by reovirus FAST proteins enhances replication and pathogenicity of non-enveloped dsRNA viruses. Kanai Y., et al., PLoS Pathog. (2019)15:e1007675.
  • (8) Entirely plasmid-based reverse genetics system for rotaviruses. Kanai Y., et al., PNAS. (2017)114:2349-2354.
  • (9) Reverse Genetics for Fusogenic Bat-Borne Orthoreovirus Associated with Acute Respiratory Tract Infections in Humans: Role of Outer Capsid Protein sigmaC in Viral Replication and Pathogenesis. Kawagishi T., et al., PLoS Pathog. (2016)12:e1005455.

Lab

Abe, Ryuichiro

International Research Center for Infectious Diseases

Laboratory of Bacterial Pathogenesis

Akira, Shizuo

Division of Host Defense

Department of Host Defense

Arase, Hisashi

Division of Host Defense

Department of Immunochemistry

Ebina, Hirotaka

BIKEN Innovative Vaccine Research Alliance Laboratories

Virus Vaccine Group

Fujimoto, Kosuke

Division of Infectious Disease

Department of Microbial Regulation

Hara, Eiji

Division of Cellular and Molecular Biology

Department of Molecular Biology

Horii, Toshihiro

Research Center for Infectious Disease Control

Laboratory of Malaria Vaccine Development

Iida, Tetsuya

Research Center for Infectious Disease Control

Department of Bacterial Infections

Ikawa, Masahito

Bioinformatics Center

Department of Experimental Genome Research

Ishitani, Tohru

Division of Cellular and Molecular Biology

Department of Homeostatic Regulation

Iwanaga, Shiroh

Research Center for Infectious Disease Control

Department of Molecular Protozoology

Iwasaki, Masaharu

International Research Center for Infectious Diseases

Laboratory of Emerging Viral Diseases

Kenji Kamimoto

Division of Cellular and Molecular Biology

Department of Systems Biomedical Science

Kotani, Ai

Division of Cellular and Molecular Biology

Department of Regulation of Infectious Cancer

Matsuura, Yoshiharu

Research Center for Infectious Disease Control

Laboratory of Virus Control

Murakami, Yoshiko

Division of Host Defense

Laboratory of Immunoglycobiology

Nakamura, Shota

Bioinformatics Center

Department of Infection Metagenomics

Nakatani, Yoichiro

Bioinformatics Center

Department of Biological Informatics Laboratory of Medical and Evolutionary Genomics

Standley, Daron

Bioinformatics Center

Department of Genome Informatics

Suzuki, Kazuhiro

Division of Host Defense

Department of Immune Response Dynamics

Takakura, Nobuyuki

Division of Cellular and Molecular Biology

Department of Signal Transduction

Tsukamoto, Kentaro

International Research Center for Infectious Diseases

Laboratory of Bacterial Zoonoses

Watanabe, Tokiko

Division of Infectious Disease

Department of Molecular Virology

Yamamoto, Masahiro

Division of Infectious Disease

Department of Immunoparasitology

Yamasaki, Sho

Division of Host Defense

Department of Molecular Immunology

Yamasaki, Shotaro

Bioinformatics Center

Department of Biological Informatics Laboratory of RNA Informatics

Yoshioka, Yasuo

BIKEN Innovative Vaccine Research Alliance Laboratories

Vaccine Creation Group