Hara, Eiji
Profile
Dr. Hara received his Ph.D. from Tokyo University of Science in 1993. After working at Imperial Cancer Research Fund Laboratories, U.K. (Postdoctoral Fellow), Cancer Research UK-Paterson Institute, U.K. (Group Leader) and the Institute for Genome Research, University of Tokushima (Professor), he was appointed Division Chief in the Cancer Institute, Japanese Foundation for Cancer Research in 2008. He took his current position at RIMD from 2015.
Publication
- (1) Downregulation of cytoplasmic DNases is implicated in cytoplasmic DNA accumulation and SASP in senescent cells. Takahashi A., et al., Nat Commun. (2018) 9(1):1249
- (2) Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome. Yoshimoto S., et al., Nature (2013) 499:97-101.
- (3) DNA damage signaling triggers degradation of histone methyltransferases through APC/CCdh1 in senescent cells. Takahashi A., et al., Molecular Cell (2012) 45:123-31.
- (4) Real-time in vivo imaging of p16Ink4a reveals cross-talk with p53. Yamakoshi K., et al., Journal of Cell Biology (2009) 186:393-407.
- (5) Mitogenic signalling and the p16INK4a- Rb pathway cooperate to enforce irreversible cellular senescence. Takahashi A., et al., Nature Cell Biology (2006) 8:1291-7.
- (6) Opposing effects of Ets and Id proteins on p16INK4a expression during cellular senescence. Ohtani N., et al., Nature (2001) 409:1067-70.
Abe, Ryuichiro
International Research Center for Infectious Diseases
Laboratory of Bacterial Pathogenesis
Akira, Shizuo
Division of Host Defense
Department of Host Defense
Arase, Hisashi
Division of Host Defense
Department of Immunochemistry
Ebina, Hirotaka
BIKEN Innovative Vaccine Research Alliance Laboratories
Virus Vaccine Group
Fujimoto, Kosuke
Division of Infectious Disease
Department of Microbial Regulation
Horii, Toshihiro
Research Center for Infectious Disease Control
Laboratory of Malaria Vaccine Development
Iida, Tetsuya
Research Center for Infectious Disease Control
Department of Bacterial Infections
Ikawa, Masahito
Bioinformatics Center
Department of Experimental Genome Research
Ishitani, Tohru
Division of Cellular and Molecular Biology
Department of Homeostatic Regulation
Iwanaga, Shiroh
Research Center for Infectious Disease Control
Department of Molecular Protozoology
Iwasaki, Masaharu
International Research Center for Infectious Diseases
Laboratory of Emerging Viral Diseases
Kenji Kamimoto
Division of Cellular and Molecular Biology
Department of Systems Biomedical Science
Kobayashi, Takeshi
Research Center for Infectious Disease Control
Department of Virology
Kotani, Ai
Division of Cellular and Molecular Biology
Department of Regulation of Infectious Cancer
Matsuura, Yoshiharu
Research Center for Infectious Disease Control
Laboratory of Virus Control
Murakami, Yoshiko
Division of Host Defense
Laboratory of Immunoglycobiology
Nakamura, Shota
Bioinformatics Center
Department of Infection Metagenomics
Nakatani, Yoichiro
Bioinformatics Center
Department of Biological Informatics Laboratory of Medical and Evolutionary Genomics
Standley, Daron
Bioinformatics Center
Department of Genome Informatics
Suzuki, Kazuhiro
Division of Host Defense
Department of Immune Response Dynamics
Takakura, Nobuyuki
Division of Cellular and Molecular Biology
Department of Signal Transduction
Tsukamoto, Kentaro
International Research Center for Infectious Diseases
Laboratory of Bacterial Zoonoses
Watanabe, Tokiko
Division of Infectious Disease
Department of Molecular Virology
Yamamoto, Masahiro
Division of Infectious Disease
Department of Immunoparasitology
Yamasaki, Sho
Division of Host Defense
Department of Molecular Immunology
Yamasaki, Shotaro
Bioinformatics Center
Department of Biological Informatics Laboratory of RNA Informatics
Yoshioka, Yasuo
BIKEN Innovative Vaccine Research Alliance Laboratories
Vaccine Creation Group
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