業績(2015年)

原著論文

1. Hirai T, Yoshioka Y(コレスポンディングオーサー), Takahashi H, Ichihashi K, Udaka A, Mori T, Nishijima N, Yoshida T, Nagano K, Kamada H, Tsunoda S, Takagi T, Ishii K, Nabeshi H, Yoshikawa T, Higashisaka K, Tsutsumi Y. Cutaneous exposure to agglomerates of silica nanoparticles and allergen results in IgE-biased immune response and increased sensitivity to anaphylaxis in mice. Part Fibre Toxicol. 2015 Jun 26;12:16.

2. Yoshida T, Yoshioka Y(コレスポンディングオーサー), Morishita Y, Aoyama M, Tochigi S, Hirai T, Tanaka K, Nagano K, Kamada H, Tsunoda S, Nabeshi H, Yoshikawa T, Higashisaka K, Tsutsumi Y. Protein corona changes mediated by surface modification of amorphous silica nanoparticles suppress acute toxicity and activation of intrinsic coagulation cascade in mice. Nanotechnology. 2015 Jun 19;26(24):245101.

3. Nagano K, Imai S, Zhao X, Yamashita T, Yoshioka Y, Abe Y, Mukai Y, Kamada H, Nakagawa S, Tsutsumi Y, Tsunoda S. Identification and evaluation of metastasis-related proteins, oxysterol binding protein-like 5 and calumenin, in lung tumors. Int J Oncol. 2015 Jul;47(1):195-203.

4. Inoue M, Kamada H, Abe Y, Higashisaka K, Nagano K, Mukai Y, Yoshioka Y, Tsutsumi Y, Tsunoda S. Aminopeptidase P3, a new member of the TNF-TNFR2 signaling complex, induces phosphorylation of JNK1 and JNK2. J Cell Sci. 2015 Feb 15;128(4):656-69.

5. Kamada H, Taki S, Nagano K, Inoue M, Ando D, Mukai Y, Higashisaka K, Yoshioka Y, Tsutsumi Y, Tsunoda S. Generation and characterization of a bispecific diabody targeting both EPH receptor A10 and CD3. Biochem Biophys Res Commun. 2015 Jan 24;456(4):908-12.

6. Isoda K, Kondoh M, Yoshioka Y, Tsutsumi Y, Imazawa T, Nishimura T, Ishida I, Yagi K. Silica nanoparticle-induced toxicity in mouse lung and liver imaged by electron microscopy. Fund Toxicol Sci. 2015;2(1):19-23.

7. Wakimoto T, Uchida K, Mimura K, Kanagawa T, Mehandjiev TR, Aoshima H, Kokubo K, Mitsuda N, Yoshioka Y, Tsutsumi Y, Kimura T, Yanagihara I. Hydroxylated Fullerene: a potential anti-inflammatory and anti-oxidant agent for preventing mouse preterm birth. Am J Obstet Gynecol. 2015 Jul 18.

8. Taki S, Kamada H, Inoue M, Nagano K, Mukai Y, Higashisaka K, Yoshioka Y, Tsutsumi Y, Tsunoda S. A Novel Bispecific Antibody against Human CD3 and Ephrin Receptor A10 for Breast Cancer Therapy. PLoS One. 2015 Dec 17;10(12):e0144712.

総説・書籍など

1. Hirai T, Yoshioka Y, Higashisaka K, Tsutsumi Y. Potential hazards of skin exposure to nanoparticles. "Biological Effects of Fibrous and Particulate Substances" by Springer. in press.

2. Morishita Y, Yoshioka Y, Higashisaka K, Tsutsumi Y. Reproductive and developmental effects of nanomaterials. "Biological Effects of Fibrous and Particulate Substances" by Springer. in press.

3. Higashisaka K, Yoshioka Y, Tsutsumi Y. Applications and safety of nanomaterials used in the food industry. Food Safety. in press.

招待講演国内)
1. 吉岡靖雄、堤 康央. サイトカインシグナルを標的とした新規粘膜ワクチンアジュバントの開発に向けて. 日本薬学会第135年会. 2015年3月28日. 神戸

2. 吉岡靖雄、堤 康央. ナノ粒子曝露に着眼したアレルギー発症要因の理解に向けて. 第88回日本産業衛生学会 アレルギー・免疫毒性研究会. 2015年5月14日. 大阪

3. 吉岡靖雄、東阪和馬、堤 康央. Sustainable Nanotechnologyを目指したナノ安全科学研究. 第42回日本毒性学会学術年会. 2015年6月29日. 金沢

4. 吉岡靖雄、東阪和馬、堤 康央. 金属系ナノマテリアルのナノ安全科学研究~Sustainable Nanotechnologyを目指して~. 第26回日本微量元素学会学術集会. 2015年7月5日. 札幌

5. 吉岡靖雄、東阪和馬、堤 康央. 脆弱な個体をも対象としたナノ安全科学研究~Sustainable Nanotechnologyを目指して~. 第55回日本先天異常学会学術集会. 2015年7月27日. 横浜

招待講演(国外)
1. Yoshioka Y, Tsutsumi Y. Understanding of immunotoxicity of engineered nanomaterials for the sustainable nanotechnology. The 31st International Congress on Occupational Health. June 2, 2015. Seoul, Korea.

2. Yoshioka Y, Higashisaka K, Tsutsumi Y. Elucidation of immunotoxicity of nanoparticles for developing the sustainable nanotechnology. The 2015 International Chemical Congress of Pacific Basin Societies (Pacifichem 2015). December 15, 2015. Honolulu, Hawaii.