Research Activities

Decoy receptor protects against Omicron infection(Okamoto Lab & Daron Lab, in Sci. Trans. Med)

Researchers from Japan find that an engineered version of the SARS-CoV-2 receptor, angiotensin-co...

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Coughing mice and the fight against pertussis (Horiguchi Lab, in mBio)

Researchers from Osaka University uncover the specific molecular mechanism behind how the whoopin...

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Genome-wide CRISPR screen reveals CLPTM1L as a lipid scramblase required for efficient glycosylphosphatidylinositol biosynthesis (Kinoshita Lab, in PNAS)

Glycosylphosphatidylinositols (GPIs) are complex glycolipids that act as membrane anchors of many...

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Zebrafish imaging reveals TP53 mutation switching oncogene-induced senescence from suppressor to driver in primary tumorigenesis (Ishitani Lab, in Nat. Commun.)

Most tumours are thought to arise through oncogenic cell generation followed by additional mutati...

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Abrogation of self-tolerance by misfolded self-antigens complexed with MHC class II molecules (Arase Lab, in Science Advances)

Gravesʼ disease is an autoimmune disease in which autoantibodies against thyroid-stimulating horm...

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SARS-CoV-2 infection triggers paracrine senescence and leads to a sustained senescence-associated inflammatory response (Hara Lab, in Nat Aging )

Reports of "post-acute COVID-19 syndrome," in which the inflammatory response persists ...

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