Research Activities

CXCR4 regulates Plasmodium development in mouse and human hepatocytes (Yamamoto Lab, in JEM)

The liver stage of the etiological agent of malaria, Plasmodium, is obligatory for successful inf...

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Cell–cell fusion induced by reovirus FAST proteins enhances replication and pathogenicity of non-enveloped dsRNA viruses

Fusogenic reoviruses encode fusion-associated small transmembrane (FAST) protein, which induces c...

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Key Amino Acid Substitution for Infection- Enhancing Activity-Free Designer Dengue Vaccines

Dengue is a globally important disease caused by four serotypes of dengue virus. Dengue vaccine d...

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Regnase-1-mediated post-transcriptional regulation is essential for hematopoietic stem and progenitor cell homeostasis

The balance between self-renewal and differentiation of hematopoietic stem and progenitor cells (...

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Vibrio parahaemolyticus injects an exotoxin into host cells to evoke diarrhea (from Iida lab, in Nat Microbiol)

Vibrio parahaemolyticus is a Gram-negative marine bacterium that causes acute, seafood-associated...

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TAK1 Prevents Endothelial Apoptosis and Maintains Vascular Integrity (Takakura Lab, in Dev. Cell)

TNFα is a pleiotropic cytokine which has potential to induce apoptosis under inflammat...

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