Research Activities
Development of Single-Round Infectious Rotaviruses as a Platform for Safer and More Effective Vaccines (Kobayashi Lab, in PLOS Pathogens)
Rotavirus remains a leading cause of acute gastroenteritis in infants worldwide, prompting contin...
A Key Role for PKD Activation in NKT Cell Development Unveiled (Yamasaki Lab, in JEM)
Development of invariant natural killer T (iNKT) cells in the thymus requires cell-cell interacti...
GALNTL5: Key to sperm migration and fertilization (Ikawa Lab, in Nat. Commun.)
More than 20 genes expressed in the male reproductive tract have been identified as essential fac...
Breaking the code of sperm motion: Two proteins found to be vital for male fertility (Ikawa Lab, in Nat. Commun)
There are many potential causes of infertility, and it can be challenging to pin down just what t...
Development of an mRNA-LNP Vaccine with Reduced Adverse Effects (Yoshioka Lab, in ACS Nano)
Messenger RNA (mRNA) vaccines effectively induce antibody production and T cell responses. Howeve...
Vasoprotective effects of lysophosphatidic acid inhibit vascular injury caused by SARS-CoV-2 infection (Takakura Lab, in Sci. Rep)
Vasculitis and vascular injury are induced in coronavirus disease 2019 (COVID-19) patients, sugge...
New method to study embryonic implantation offers hope for assisted reproduction (Ikawa Lab, in Nat. Commun.)
The use of assisted reproductive technologies like in vitro fertilization is becoming more common...
Evolutionary dynamics of heparan sulfate utilization by SARS-CoV-2 (Arase Lab, in mBio)
The SARS-CoV-2 Omicron variant acquired high infectivity through more than 30 mutations in its sp...
Transferrin and ferritin regulate cell cycle of lymphoma cells at different points (Kotani Lab, Redox Biology)
Although is widely known that iron is important for the survival and proliferation of cells ...
RIFINs Bind Both Inhibitory and Activating NK Receptors (Iwanaga Lab, Nature)
Malaria is a life-threatening disease affecting people globally. It is spread by mosquitoes carry...
Rotavirus VP4/VP7 monoreassortants reveal genotypes less sensitive to vaccine- or infection-induced antibodies (Kobayashi Lab, in mBio)
Rotavirus, the leading cause of severe acute gastroenteritis in infants, is responsible for appro...
Uncovering the protein complex critical to male fertility (Ikawa Lab, in PNAS)
The human body is full of checks and balances that ensure correct growth, development, and functi...
Establishment of reverse genetics systems for Colorado tick fever virus（Kobayashi Lab, in PLOS Pathogens)
The Colorado tick fever virus (CTFV), which has 12-segmented double-stranded RNA genomes, is a pa...
Identification of a New T cell Subset Fighting Mycobacterium Tuberculosis (Yamasaki Lab, JCI)
Mycobacterium tuberculosis causes human tuberculosis. As mycobacteria are protected by thick...
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