／Research Collaboration Center for Infectious Diseases Mahidol-Osaka Center for Infectious Diseases
The Mahidol-Osaka Center for Infectious Diseases (MOCID) focuses on several tropical infectious diseases that are of importance to human health in Thailand. Mosquito-borne viral infectious diseases such as dengue fever/dengue hemorrhagic fever and chikungunya fever are of particular interest. We are currently developing rapid diagnosis kits and are examining factors that affect disease severity. We would like to improve the research skills of young scientists and increase their interest in infectious diseases by collaborating with Mahidol University, which provides clinical samples.
- Director of MOCID,Prof. (concur.): Tatsuo Shioda
- 1. lntraperitoneal injection with dengue virus type 1-infected K562 cells results in complete fatality among immunocompetent mice. Yamanaka A. Konishi E. Antiviral Res. (2Cl19) 170:104560.
2. Key Amino Acid Substitution for Infection-Enhancing Activity-Free Designer Dengue Vaccines. Yamanaka A, Konishi E. iScience. (2019) 13:125-137,
3. High-throughput neutralization assay for multipleflaviviruses based on single-round infectious particles using dengue virus type 1 reporter replicon. Matsuda M, et al.. Sci Rep.(2018) 8(1):16624.
4. Dengue-Immune Humans Have Higher Levels of Complement-Independent Enhancing Antibody than Complement-Dependent Neutralizing Antibody. Yamanaka A. Konishi E. Jpn J Infect Dis.(2017) 70(5):579·581 .