Research Activities
Human norovirus propagation in iPS cell-derived intestinal epithelial cells (Sato Lab, in CMGH)
Human norovirus (HuNoV) is a major cause of intestinal infection, with diarrhea and vomiting. The...
Group A <i>Streptococcus<i> converts PAMPs to immunosuppressive lipids to evade host immunity (Yamasaki_Lab, in PNAS)
Group A Streptococcus (GAS) is a Gram-positive bacterial pathogen that causes a range of diseases...
Inducible Nitric Oxide Synthase Is a Key Host Factor for Toxoplasma GRA15-Dependent Disruption of the Gamma Interferon-Induced Antiparasitic Human Response (Yamamoto Lab, in mBio)
Toxoplasma, an important intracellular parasite of humans and animals, causes life-threateni...
Infection with flaviviruses requires BCLXL for cell survival (Matsuura-Lab in PLoS Pathogens)
The genus Flavivirus including Japanese encephalitis virus, Dengue virus, and Zika virus all of w...
Identification of proteins important for enterotoxigenic Escherichia coli colonization. (Nakamura lab. in PNAS)
Enterotoxigenic Escherichia coli (ETEC) is known to be the leading cause of diarrhea in travelers...
Downregulation of cytoplasmic DNases is implicated in cytoplasmic DNA accumulation and SASP in senescent cells (Hara Lab, in Nat Commun)
Although the irreversible cell-cycle arrest is traditionally believed as the major function of se...
Identification of vascular endothelial stem cells (Takakura Lab, in Cell Stem Cell)
The generation of new blood vessels via angiogenesis is critical for meeting tissue oxygen demand...
Identification of a Golgi GPI-N-acetylgalactosamine transferase (Kinnoshita Lab, in Nature Commun.)
About 150 various proteins are anchored to the mammalian cell surface via a glycolipid, termed gl...
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