Osaka University COE − Institut Pasteur
Joint Youth Meeting on Infectious Diseases and Immunology

大阪大学21世紀COEプログラム
「感染症学・免疫学融合プログラム」―　フランスパスツール研究所
感染症・免疫学　日仏若手研究交流シンポジウム

日時：　2006年2月16日（木）〜17日（金）
場所：　大阪大学銀杏会館
　　　　http://www.med.osaka-u.ac.jp/pub/general/alumni/intro-jp.html
参加費：無料（事前登録不要）
主催：　21世紀COEプログラム「感染症学・免疫学融合プログラム」
　　　　大阪大学
　　　　医学系研究科
　　　　微生物病研究所

プログラム
February 16 (Thu)

9:00 ~ 9:20 Opening Remarks
　Shizuo Akira (Leader of the COE program, Osaka Univ.)
　"The 21st century COE "Combined program on microbiology and immunology""
9:20 ~ 10:20 Session I (Bacterial virulence factors)
　Shaynoor Dramsi (Inst. Pasteur)
　 " Assembly and Role of Pili in Group B Streptococci "
　Hideki Katayama (Fukuoka Industrial Technology Center)
　 " Parasporin-1, a novel cytotoxin from Bacillus thuringiensis, evokes Ca2+ influx in mammalian cells "
　Aya Fukui (Osaka Univ.)
　 "Structure-function relationship of Bordetella dermonecrotic toxin"

10:40 ~ 12:00 Session II (Mycobacteria and Candida)
　Marco Bellinzoni (Inst. Pasteur)
　 "Ser/Thr phosphorylation in mycobacteria: a genetic and structural approach"
　Yasuhiro Morita (Osaka Univ.)
　 "A mannosyltransferase involved in phosphatidylinositol mannoside biosynthesis in Mycobacterium smegmatis"
　Laurent Marsollier (Inst. Pasteur)
" Ecology and transmission of Mycobacterium ulcerans "
　Emilia Moreno-Ruiz (Inst. Pasteur)
" Genomic approaches to the study of biofilm formation by the fungal pathogen of humans, Candida albicans"

13:40 ~14:40 Keynote Lecture I
　Shizuo Akira (Osaka Univ.)
　 "Sensing mechanism of viral infection in innate immunity"
14:40 ~ 15:40 Session III (Host defense)
　Ikuo Shiratori (Osaka Univ.)
　 "Downregulation of basophil function by human and viral CD200"
　Mustapha Si-Tahar (Inst. Pasteur)
　 " The Toll-like receptor (TLR)-3 contributes to influenza A virus-induced acute respiratory disease "
　Ken J Ishii (Osaka Univ.)
　 "A TLR-independent antiviral response induced by double-stranded B-DNA"

16:00 ~ 16:40 Session IV (Cross-talk between the immune system and the nervous system)
　Sylvie Memet (Inst. Pasteur)
　 " Genetic approaches to unravel the role of the transcription factor NF-κB in immunity and brain function "
　Noriko Takegahara (Osaka Univ.)
　 "Plexin-A1 associates with Trem-2/DAP12 receptor complex and mediates the activities of Sema6D on DCs"

16:40 ~ 18:00 Session V (Viruses)
　Takayuki Abe (Osaka Univ.)
　 "Modulation of Toll-like receptor signaling in immune cells by expression of hepatitis C virus non-structural proteins"
　Masaya Takemoto (National Inst. Biomedical Innovation)
　 "Human Herpesvirus 7 increases CD46 expression on the infected cell surfaces"
　Sanae Shoji (Osaka Univ.)
　 "E3 ubiquitin protein ligase RNF125 inhibits human immunodeficiency virus type 1 replication"
　Jun-ichi Sakuragi (Osaka Univ.)
　 "Genome dimerization of HIV-1 and its roles for viral replication"

18:15 ~ Mixer

February 17 (Fri)

9:00 ~ 10:20 Session VI (Lymphocyte development, migration and activation)
　Gerard Eberl (Inst. Pasteur)
　 " Lymphoid tissue inducer cells in the fetus and the adult gut"
　Akiko Shigeta (Osaka Univ.)
　 "Generation and analysis of PSGL-1 and L-selectin double-deficient mice"
　Philippe Bousso (Inst. Pasteur)
　 "Dynamics of T cell activation in vivo"
　Eiji Umemoto (Osaka Univ.)
　 "Nepmucin, a novel sialomucin with an Ig domain mediates L-selectin-dependent lymphocyte rolling and promotes lymphocyte adhesion under flow"

10:40 ~ 11:40 Session VII (Malaria)
　Nicola K. Viebig (Inst. Pasteur)
　 " Placental malaria, a paradigm for the development of an anti disease vaccine"
　Ali Jafarshad (Inst. Pasteur)
　 " Characterisation of the antibody-dependent monocyte-mediated mechanism of defence against malaria "
　Nobuko Arisue (Osaka Univ.)
　 "Evolution and phylogenetic relationship of SERA family genes in Plasmodium species"

13:20 ~ 14:20 Keynote Lecture II
　Toshihiro Horii (Osaka Univ.)
　 "Clinical development of the SE36 malaria vaccine targeting the Achilles heel antigen of Plasmodium falciparum"

14:20 ~16:20 (incl 20-min break) Session VIII (Bacterial Infections)
　Hiroyuki Abe (Osaka Univ.)
　 "Identification and characterization of ECs1814, a novel type III translocated effector of enterohaemorrhagic Escherichia coli O157:H7"
　Vlademir V. Cantarelli (Osaka Univ.)
　 "A delicate balance between tyrosine phosphorylation/dephosphorylation of cortactin controls pedestal formation induced by EPEC and EHEC"
　Ivo G. Boneca (Inst. Pasteur)
　 "How bacteria are sensed and evade the Nod proteins"
　Hiroki Nagai (Osaka Univ.)
　 "Interplay of Legionella pneumophila and its eukaryotic host cells"
　Olivier Dussurget (Inst. Pasteur)
　 " Pathophysiology of Listeria monocytogenes Infection : insight from the genome "

16:20 ~ Closing Remarks: Toshihiro Horii (Osaka Univ.)

【事務局】
大阪大学微生物病研究所
分子細菌学分野　
堀口安彦
〒565-0871
大阪府吹田市山田丘3―1
TEL: 06-6879-8284
FAX:06-6879-8283
Email: horiguti@biken.osaka-u.ac.jp