助教 斎藤 達哉
Tatsuya Saitoh Ph.D.
13) Matsunaga K, Saitoh T, Tabata
K, Omori H, Satoh T, Maejima I, Shirahama-Noda K, Ichimura T, Isobe T, Akira
S, Noda T, Yoshimori T. Two Beclin 1-binding proteins, Atg14L and Rubicon,
reciprocally regulate autophagy at different stages. Nat Cell Biol. 2009
Mar 8. [Epub ahead of print]
12) Saitoh T*, Fujita N*, Jang MH, Uematsu S, Yang BG, Satoh T, Omori H, Noda T, Yamamoto N, Komatsu M, Tanaka K, Kawai T, Tsujimura T, Takeuchi O, Yoshimori T, Akira S. Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production. Nature. 2008 Oct 5. [Epub ahead of print] (*contributed equally)
11) Kawagoe T, Sato S, Matsushita K, Kato H, Matsui K, Kumagai Y, Saitoh T, Kawai T, Takeuchi O, Akira S. Sequential control of Toll-like receptor-dependent responses by IRAK1 and IRAK2. Nat Immunol. 2008 Apr 27; [Epub ahead of print]
10) Saitoh Y, Yamamoto N, Dewan MZ, Sugimoto H, Martinez B VJ, Iwasaki Y, Matsubara K, Qi X, Saitoh T , Imoto I, Inazawa J, Utsunomiya A, Watanabe T, Masuda T, Yamamoto N, Yamaoka S. Overexpressed NF-{kappa}B inducing kinase contributes to the tumorigenesis of adult T-cell leukemia and Hodgkin Reed-Sternberg cells. Blood. 2008 Feb 27; [Epub ahead of print]
9) Yamamoto M, Uematsu S, Okamoto T, Matsuura Y, Sato S, Kumar H, Satoh T, Saitoh T, Takeda K, Ishii KJ, Takeuchi O, Kawai T, Akira S. Enhanced TLR-mediated NF-IL6 dependent gene expression by Trib1 deficiency. J Exp Med. 2007 Aug 27; [Epub ahead of print]
8) Qi X, Koya Y, Saitoh T , Saitoh Y, Shimizu S, Ohba K, Yamamoto N, Yamaoka S, Yamamoto N. Efficient induction of HIV-1 replication in latently infected cells through contact with CD4+ T cells: involvement of NF-kappaB activation. Virology. 2007 May 10;361(2):325-34. Epub 2007 Jan 10.
7) Yamamoto M, Sato S, Saitoh T, Sakurai H, Uematsu S, Kawai T, Ishii KJ, Takeuchi O, Akira S. Cutting Edge: Pivotal Function of Ubc13 in Thymocyte TCR Signaling. J Immunol. 2006 Dec 1;177(11):7520-4.
6) Yamamoto M, Okamoto T, Takeda K, Sato S, Sanjo H, Uematsu S, Saitoh T, Yamamoto N, Sakurai H, Ishii KJ, Yamaoka S, Kawai T, Matsuura Y, Takeuchi O, Akira S. Key function for the Ubc13 E2 ubiquitin-conjugating enzyme in immune receptor signaling. Nat Immunol. 2006 Jul 23; [Epub ahead of print]
5) Saitoh T, Tun-Kyi A, Ryo A, Yamamoto M, Finn G, Fujita T, Akira S, Yamamoto N, Lu KP, Yamaoka S. Negative regulation of interferon-regulatory factor 3-dependent innate antiviral response by the prolyl isomerase Pin1. Nat Immunol. 2006 Jun;7(6):598-605. Epub 2006 May 14
4) Saitoh T, Yamamoto M, Miyagishi M, Taira K, Nakanishi M, Fujita T, Akira S, Yamamoto N, Yamaoka S. A20 is a negative regulator of IFN regulatory factor 3 signaling. J Immunol. 2005 Feb 1;174(3):1507-12.
3) Saitoh T, Nakayama M, Nakano H, Yagita H, Yamamoto N, Yamaoka S. TWEAK induces NF-kappaB2 p100 processing and long lasting NF-kappaB activation. J Biol Chem. 2003 Sep 19;278(38):36005-12. Epub 2003 Jul 1
2) Saitoh T, Nakano H, Yamamoto N, Yamaoka S. Lymphotoxin-beta receptor mediates NEMO-independent NF-kappaB activation. FEBS Lett. 2002 Dec 4;532(1-2):45-51.
1) Saitoh T, Tanaka S, Koike T. Rapid induction and Ca(2+) influx-mediated suppression of vitamin D3 up-regulated protein 1 (VDUP1) mRNA in cerebellar granule neurons undergoing apoptosis. J Neurochem. 2001 Sep;78(6):1267-76.
12) Saitoh T*, Fujita N*, Jang MH, Uematsu S, Yang BG, Satoh T, Omori H, Noda T, Yamamoto N, Komatsu M, Tanaka K, Kawai T, Tsujimura T, Takeuchi O, Yoshimori T, Akira S. Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production. Nature. 2008 Oct 5. [Epub ahead of print] (*contributed equally)
11) Kawagoe T, Sato S, Matsushita K, Kato H, Matsui K, Kumagai Y, Saitoh T, Kawai T, Takeuchi O, Akira S. Sequential control of Toll-like receptor-dependent responses by IRAK1 and IRAK2. Nat Immunol. 2008 Apr 27; [Epub ahead of print]
10) Saitoh Y, Yamamoto N, Dewan MZ, Sugimoto H, Martinez B VJ, Iwasaki Y, Matsubara K, Qi X, Saitoh T , Imoto I, Inazawa J, Utsunomiya A, Watanabe T, Masuda T, Yamamoto N, Yamaoka S. Overexpressed NF-{kappa}B inducing kinase contributes to the tumorigenesis of adult T-cell leukemia and Hodgkin Reed-Sternberg cells. Blood. 2008 Feb 27; [Epub ahead of print]
9) Yamamoto M, Uematsu S, Okamoto T, Matsuura Y, Sato S, Kumar H, Satoh T, Saitoh T, Takeda K, Ishii KJ, Takeuchi O, Kawai T, Akira S. Enhanced TLR-mediated NF-IL6 dependent gene expression by Trib1 deficiency. J Exp Med. 2007 Aug 27; [Epub ahead of print]
8) Qi X, Koya Y, Saitoh T , Saitoh Y, Shimizu S, Ohba K, Yamamoto N, Yamaoka S, Yamamoto N. Efficient induction of HIV-1 replication in latently infected cells through contact with CD4+ T cells: involvement of NF-kappaB activation. Virology. 2007 May 10;361(2):325-34. Epub 2007 Jan 10.
7) Yamamoto M, Sato S, Saitoh T, Sakurai H, Uematsu S, Kawai T, Ishii KJ, Takeuchi O, Akira S. Cutting Edge: Pivotal Function of Ubc13 in Thymocyte TCR Signaling. J Immunol. 2006 Dec 1;177(11):7520-4.
6) Yamamoto M, Okamoto T, Takeda K, Sato S, Sanjo H, Uematsu S, Saitoh T, Yamamoto N, Sakurai H, Ishii KJ, Yamaoka S, Kawai T, Matsuura Y, Takeuchi O, Akira S. Key function for the Ubc13 E2 ubiquitin-conjugating enzyme in immune receptor signaling. Nat Immunol. 2006 Jul 23; [Epub ahead of print]
5) Saitoh T, Tun-Kyi A, Ryo A, Yamamoto M, Finn G, Fujita T, Akira S, Yamamoto N, Lu KP, Yamaoka S. Negative regulation of interferon-regulatory factor 3-dependent innate antiviral response by the prolyl isomerase Pin1. Nat Immunol. 2006 Jun;7(6):598-605. Epub 2006 May 14
4) Saitoh T, Yamamoto M, Miyagishi M, Taira K, Nakanishi M, Fujita T, Akira S, Yamamoto N, Yamaoka S. A20 is a negative regulator of IFN regulatory factor 3 signaling. J Immunol. 2005 Feb 1;174(3):1507-12.
3) Saitoh T, Nakayama M, Nakano H, Yagita H, Yamamoto N, Yamaoka S. TWEAK induces NF-kappaB2 p100 processing and long lasting NF-kappaB activation. J Biol Chem. 2003 Sep 19;278(38):36005-12. Epub 2003 Jul 1
2) Saitoh T, Nakano H, Yamamoto N, Yamaoka S. Lymphotoxin-beta receptor mediates NEMO-independent NF-kappaB activation. FEBS Lett. 2002 Dec 4;532(1-2):45-51.
1) Saitoh T, Tanaka S, Koike T. Rapid induction and Ca(2+) influx-mediated suppression of vitamin D3 up-regulated protein 1 (VDUP1) mRNA in cerebellar granule neurons undergoing apoptosis. J Neurochem. 2001 Sep;78(6):1267-76.