ポスドク(JSPS)
Himanshu Kumar （ヒマンシュ・クマール）Ph.D.
メール を 出す
ポスドク(JSPS)
Himanshu Kumar （ヒマンシュ・クマール）Ph.D.
メール を 出す
13) Kumagai Y, Kumar H, Koyama S, Kawai T, Takeuchi O, Akira S.
Cutting Edge: TLR-Dependent viral recognition along with type I IFN positive
feedback signaling masks the requirement of viral replication for IFN-{alpha}
production in plasmacytoid dendritic cells. J Immunol. 2009 Apr 1;182(7):3960-4.
12) Lee PY, Kumagai Y, Li Y, Takeuchi O, Yoshida H, Weinstein J, Kellner
ES, Nacionales D, Barker T, Kelly-Scumpia K, van Rooijen N, Kumar H
, Kawai T, Satoh M, Akira S, Reeves WH. TLR7-dependent and Fc{gamma}R-independent
production of type I interferon in experimental mouse lupus. J Exp Med.
2008 Dec 1. [Epub ahead of print]
11) Ishii KJ*, Kawagoe T*, Koyama S,
Matsui K, Kumar H, Kawai
T, Uematsu S, Takeuchi O, Takeshita F, Coban C, Akira S. TANK-binding kinase-1
delineates innate and adaptive immune responses to DNA vaccines. Nature.
2008 Feb 7;451(7179):725-729. (*contributed equally)
10) Kumar H*, Koyama
S*, Ishii KJ, Kawai T, Akira S. Cooperation of IPS-1- and TRIF-Dependent
Pathways in Poly IC-Enhanced Antibody Production and Cytotoxic T Cell Responses.
J Immunol. 2008 Jan 15;180(2):683-7. (*contributed equally)
9) Jung A, Kato H, Kumagai Y, Kumar H, Kawai T, Takeuchi O, Akira S. Lymphocytoid choriomeningitis virus activates plasmacytoid dendritic cells and induces cytotoxic T cell response via MyD88. J Virol. 2007 Oct 17; [Epub ahead of print]
8) Koyama S, Ishii KJ, Kumar H, Tanimoto T, Coban C, Uematsu S, Kawai T, Akira S. Differential Role of TLR- and RLR-Signaling in the Immune Responses to Influenza A Virus Infection and Vaccination. J Immunol. 2007 Oct 1;179(7):4711-20.
7) Yamamoto M, Uematsu S, Okamoto T, Matsuura Y, Sato S,
Kumar H, Satoh T, Saitoh T, Takeda K, Ishii KJ, Takeuchi O, Kawai
T, Akira S. Enhanced TLR-mediated NF-IL6 dependent gene expression by Trib1
deficiency. J Exp Med. 2007 Aug 27; [Epub ahead of print]
6) Kumagai Y, Takeuchi O, Kato H,
Kumar H, Matsui K, Morii E, Aozasa K, Kawai T, Akira S. Alveolar
Macrophages Are the Primary Interferon-alpha Producer in Pulmonary Infection
with RNA Viruses. Immunity. 2007 Aug;27(2):240-52.
5) Roberts ZJ, Goutagny N, Perera PY, Kato H,
Kumar H, Kawai T, Akira S, Savan R, van
Echo D, Fitzgerald KA, Young HA, Ching LM, Vogel SN. The chemotherapeutic
agent DMXAA potently and specifically activates the TBK1-IRF-3 signaling
axis. J Exp Med. 2007 Jun 11; [Epub ahead of print]
4) Bhattacharjee RN, Park KS, Kumagai Y, Okada K, Yamamoto M, Uematsu
S, Matsui K, Kumar H, Kawai T, Iida T, Honda T, Takeuchi O, Akira
S. VP1686, a Vibrio type III secretion protein, induces toll-like receptor
independent apoptosis in macrophage through NF-kappa B inhibition. J Biol
Chem. 2006 Sep 19; [Epub ahead of print]
3) Kumar H*, Kawai T*, Kato H, Sato S, Takahashi K, Coban C, Yamamoto M, Uematsu S, Ishii KJ, Takeuchi O, Akira S (*equal contribution). Essential role of IPS-1 in innate immune responses against RNA viruses. J Exp Med. 2006 Jun 19; [Epub ahead of print]
2) Takahashi K, Kawai T, Kumar H, Sato S, Yonehara S, Akira S. Cutting edge: roles of caspase-8 and caspase-10 in innate immune responses to double-stranded RNA. J Immunol. 2006 Apr 15;176(8):4520-4.
1) Kawai T, Takahashi K, Sato S, Coban C, Kumar H, Kato H, Ishii KJ, Takeuchi O, Akira S. IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction. Nat Immunol. 2005 Oct;6(10):981-8. Epub 2005 Aug 28