Department of Celluar Regulation

1. Redox signaling by reversible protein oxidation.
2. Promotion of cancer metastasis by PRL.
3. Regulatory mechanism and functional importance of the magnesium level.

1. Phosphorylation of Kif26b promotes its polyubiquitination and subsequent proteasomal degradation during kidney development.

   Takeshi Terabayashi, Masaji Sakaguchi, Kaori Shinmyozu, Toshio Ohshima, Ai Johjima, Teru Ogura, Hiroaki Miki and Ryuichi Nishinakamura

   PLoS One, 7 (6), e39714, 2012.
2. Regulation of intracellular signalling through cysteine oxidation by reactive oxygen species.

   Hiroaki Miki and Yosuke Funato

   J Biochem, 151 (3), 255-261, 2012.

Link

http://www.biken.osaka-u.ac.jp/