Department of Molecular Genetics

Subjects:

1. Molecular mechanisms regulating the cell cycle in mammalian cells.
2. Molecular mechanisms controlling the meiosis in fission yeast.
3. Molecular mechanisms modulating the metastasis of malignant cells.
4. Application of a new technique (stepwise subtraction) to RNA diagnosis.

Published Papers

1. Neonatal lethality in knockout mice expressing the kinase-dead form of the gefitinib target GAK is caused by pulmonary dysfunction.

   Hiroe Tabara, Yoko Naito, Akihiko Ito, Asako Katsuma, Minami A Sakurai, Shouichi Ohno, Hiroyuki Shimizu, Norikazu Yabuta and Hiroshi Nojima

   PLoS One, 6 (10), e26034, 2011.
2. Microarray analysis of tonsils of IgA nephropathy patients.

   Hirotsugu Iwatani, Kenichiro Iio, Yasuyuki Nagasawa, Ryohei Yamamoto, Arata Horii, Daisuke Okuzaki, Hidenori Inohara, Hiroshi Nojima, Enyu Imai, Hiromi Rakugi and Yoshitaka Isaka

   Adv Otorhinolaryngol, 72, 75-78, 2011.
3. LeukoCatch, a quick and efficient tool for the preparation of leukocyte extracts from blood.

   Daisuke Okuzaki, Shoichi Kimura, Norikazu Yabuta, Toshinari Ohmine and Hiroshi Nojima

   BMC Clin Pathol, 11, 9, 2011.
4. The tumor suppressor Lats2 is pivotal in Aurora A and Aurora B signaling during mitosis.

   Norikazu Yabuta, Satomi Mukai, Nobuhiro Okada, Yael Aylon and Hiroshi Nojima

   Cell Cycle, 10 (16), 2724-2736, 2011.
5. Preparation of a high-quality cDNA library from a single-cell quantity of mRNA using chum-RNA.

   Hiroshi Nojima and Takahiro Tougan

   Methods Mol Biol, 729, 15-35, 2011.
6. A novel Chk1/2-Lats2-14-3-3 signaling pathway regulates P-body formation in response to UV damage.

   Nobuhiro Okada, Norikazu Yabuta, Hirokazu Suzuki, Yael Aylon, Moshe Oren and Hiroshi Nojima

   J Cell Sci, 124 (pt.1), 57-67, 2011.

Link

http://www.biken.osaka-u.ac.jp/