Department of Molecular Bacteriology

Subjects:

1. Search for novel virulence factors produced by pathogenic bacteria.
2. Analysis of structure and function of bacterial virulence factors.

Published Papers

1. Enzymatic actions of Pasteurella multocida toxin detected by monoclonal antibodies recognizing the deamidated α subunit of the heterotrimeric GTPase Gq.

   Shigeki Kamitani, Shinpei Ao, Hirono Toshima, Taro Tachibana, Makiko Hashimoto, Kengo Kitadokoro, Aya Fukui-Miyazaki, Hiroyuki Abe and Yasuhiko Horiguchi

   FEBS J, 278 (15), 2702-2712, 2011.
2. Crystal Structure of Clostridium perfringens Enterotoxin Displays Features of β-Pore-forming Toxins.

   Kengo Kitadokoro, Kousuke Nishimura, Shigeki Kamitani, Aya Fukui-Miyazaki, Hirono Toshima, Hiroyuki Abe, Yoichi Kamata, Yoshiko Sugita-Konishi, Shigeki Yamamoto, Hajime Karatani and Yasuhiko Horiguchi

   J Biol Chem, 286 (22), 19549-19555, 2011.
3. Bordetella dermonecrotic toxin binds to target cells via the N-terminal 30 amino acids.

   Aya Fukui-Miyazaki, Shinya Ohnishi, Shigeki Kamitani, Hiroyuki Abe and Yasuhiko Horiguchi

   Microbiol Immunol, 55 (3), 154-159, 2011.

Link

http://www.biken.osaka-u.ac.jp/