Laboratory of Genomic Research on Pathogenic Bacteria

Subjects:

1. Characterization of the mechanism(s) used by bacterial pathogens to infect host organisms by identifying infection-related changes in pathogen genome expression.
2. Analysis of the mechanism(s) that lead to the emergence of new infectious diseases.
3. Investigation of the life cycles of bacterial pathogens in their natural environments.
4. Development of new methods for the rapid identification of bacterial pathogens based on genome information.

Published Papers

1. Gut microbiota of healthy and malnourished children in bangladesh.

   Shirajum Monira, Shota Nakamura, Kazuyoshi Gotoh, Kaori Izutsu, Haruo Watanabe, Nur Haque Alam, Hubert Ph Endtz, Alejandro Cravioto, Sk Imran Ali, Takaaki Nakaya, Toshihiro Horii, Tetsuya Iida and Munirul Alam

   Front Microbiol, 2, 228, 2011.
2. Identification of the Vibrio parahaemolyticus type III secretion system 2-associated chaperone VocC for the T3SS2-specific effector VopC.

   Yukihiro Akeda, Toshio Kodama, Kazunobu Saito, Tetsuya Iida, Kazunori Oishi and Takeshi Honda

   FEMS Microbiol Lett, 324 (2), 156-164, 2011.
3. Relationship between Localization on Cellular Membranes and Cytotoxicity of Vibrio vulnificus Hemolysin.

   Hiroyuki Sugiyama, Takashige Kashimoto, Shunji Ueno, Hayato Ehara, Toshio Kodama, Tetsuya Iida and Nobuyuki Susa

   PLoS One, 6 (10), e26018, 2011.
4. VopV, an F-Actin-Binding Type III Secretion Effector, Is Required for Vibrio parahaemolyticus-Induced Enterotoxicity.

   Hirotaka Hiyoshi, Toshio Kodama, Kazunobu Saito, Kazuyoshi Gotoh, Shigeaki Matsuda, Yukihiro Akeda, Takeshi Honda and Tetsuya Iida

   Cell Host Microbe, 10 (4), 401-409, 2011.
5. Recombinant AexU effector protein of Aeromonas veronii bv. sobria disrupts the actin cytoskeleton by downregulation of Rac1 and induces direct cytotoxicity to β4-integrin expressing cell lines.

   Said Kamal Abolghait, Tetsuya Iida, Toshio Kodama, Vlademir V Cantarelli, Yukihiro Akeda and Takeshi Honda

   Microb Pathog, 51 (6), 454-465, 2011.
6. Genome Sequence of the Human Pathogen Vibrio cholerae Amazonia.

   Cristiane C Thompson, Michel A Marin, Graciela M Dias, Bas E Dutilh, Robert A Edwards, Tetsuya Iida, Fabiano L Thompson and Ana Carolina P Vicente

   J Bacteriol, 193 (20), 5877-5878, 2011.
7. Metagenomic analysis of bacterial infections by means of high-throughput DNA sequencing.

   Shota Nakamura, Takaaki Nakaya and Tetsuya Iida

   Exp Biol Med (Maywood), 236 (8), 968-971, 2011.
8. Effect of N-acetyl-D-glucosamine on gene expression in Vibrio parahaemolyticus.

   Fabiano L Thompson, Antonio Alves Neto, Eidy de O Santos, Kaori Izutsu and Tetsuya Iida

   Microbes Environ, 26 (1), 61-66, 2011.

Link

http://www.biken.osaka-u.ac.jp/