Laboratory of Combined Research on Microbiology and Immunology

Subjects:

1. Structure and function of the type IV secretion system of bacterial pathogens.
2. Cellular functions of effector proteins of Legionella pneumophila.

Published Papers

1. Legionella metaeffector exploits host proteasome to temporally regulate cognate effector.

   Tomoko Kubori, Naoaki Shinzawa, Hirotaka Kanuka and Hiroki Nagai

   PLoS Pathog, 6 (12), e1001216, 2010.
2. Crystal structure of Legionella DotD: insights into the relationship between type IVB and type II/III secretion systems.

   Noboru Nakano, Tomoko Kubori, Miki Kinoshita, Katsumi Imada and Hiroki Nagai

   PLoS Pathog, 6 (10), e1001129, 2010.

Link

http://www.biken.osaka-u.ac.jp/