Department of Molecular Bacteriology

Subjects:

1. Search for novel virulence factors produced by pathogenic bacteria.
2. Analysis of structure and function of bacterial virulence factors.

Published Papers

1. Domain mapping of a claudin-4 modulator, the C-terminal region of C-terminal fragment of Clostridium perfringens enterotoxin, by site-directed mutagenesis.

   Azusa Takahashi, Eriko Komiya, Hideki Kakutani, Takeshi Yoshida, Makiko Fujii, Yasuhiko Horiguchi, Hiroyuki Mizuguchi, Yasuo Tsutsumi, Shin-ichi Tsunoda, Naoya Koizumi, Katsuhiro Isoda, Kiyohito Yagi, Yoshiteru Watanabe and Masuo Kondoh

   Biochem Pharmacol, 75 (8), 1639-1648, 2008.
2. The morphological changes in cultured cells caused by Bordetella pertussis adenylate cyclase toxin.

   Hiroe Ohnishi, Masami Miyake, Shigeki Kamitani and Yasuhiko Horiguchi

   FEMS Microbiol Lett, 279 (2), 174-179, 2008.
3. A colorimetric assay for studying effector secretion through the bacterial type III secretion system.

   Masami Miyake, Sadatsugu Sakane, Chiho Kobayashi, Miyuki Hanajima-Ozawa, Aya Fukui, Shigeki Kamitani and Yasuhiko Horiguchi

   FEMS Microbiol Lett, 278 (1), 36-42, 2008.

Link

http://www.biken.osaka-u.ac.jp/