Department of Genome Informatics

Subjects:

1. Bioinformatics and molecular evolution analysis of genes and genomes.
2. Analysis of protein 3-D structure information for drug discovery and design.
3. Genome sequencing of disease-causing organisms in collaboration with other laboratories.
4. Development of genome information analysis software.

Published Papers

1. Analysis of invariant sequences in 266 complete genomes.

   Naohisa Goto, Ken Kurokawa and Teruo Yasunaga

   Gene, 401 (1-2), 172-180, 2007.
2. Roles of a short connecting disulfide bond in the stability and function of psychrophilic Shewanella violacea cytochrome c (5).

   Keiko Ogawa, Takafumi Sonoyama, Taku Takeda, Shin-Ichi Ichiki, Shota Nakamura, Yuji Kobayashi, Susumu Uchiyama, Kaoru Nakasone, Shin-Ichi J Takayama, Hajime Mita, Yasuhiko Yamamoto and Yoshihiro Sambongi

   Extremophiles, 11 (6), 797-807, 2007.
3. Crystallization of human nicotinamide phosphoribosyltransferase.

   Ryo Takahashi, Shota Nakamura, Takuya Yoshida, Yuji Kobayashi and Tadayasu Ohkubo

   Acta Crystallogr Sect F Struct Biol Cryst Commun, 63 (Pt 5), 375-377, 2007.
4. Crystal structure of Pyrococcus horikoshii PPC protein at 1.60 A resolution.

   Linyen Lin, Hiroaki Nakano, Shota Nakamura, Susumu Uchiyama, Satoru Fujimoto, Sachihiro Matsunaga, Yuji Kobayashi, Tadayasu Ohkubo and Kiichi Fukui

   Proteins, 67 (2), 505-507, 2007.
5. The 2006 NESCent Phyloinformatics Hackathon: a field report.

   Hilmar Lapp, Sendu Bala, James P. Balhoff, Amy Bouck, Naohisa Goto, Mark Holder, Richard Holland, Alisha Holloway, Toshiaki Katayama, Paul O. Lewis, Aaron J. Mackey, Brian I. Osborne, William H. Piel, Sergei L. Kosakovsky Pond, Art F.Y. Poon, Wei-Gang Qiu, Jason E. Stajich, Arlin Stoltzfus, Tobias Thierer, Albert J. Vilella, Rutger A. Vos, Christian M. Zmasek, Derrick J. Zwickl and Todd J. Vision

   Evolutionary Bioinformatics, 3, 357-366, 2007.

Link

http://www.biken.osaka-u.ac.jp/