Laboratory of Genomic Research on Pathogenic Bacteria

Department of Infectious Diseases Control;

Subjects:

1. Characterization of the mechanism(s) used by bacterial pathogens to infect host organisms by identifying infection-related changes in pathogen genome expression.
2. Analysis of the mechanism(s) that lead to the emergence of new infectious diseases.
3. Investigation of the life cycles of bacterial pathogens in their natural environments.
4. Development of new methods for the rapid identification of bacterial pathogens based on genome information.

Published Papers

1. Tetrameric structure of thermostable direct hemolysin from vibrio parahaemolyticus revealed by ultracentrifugation, small-angle X-ray scattering and electron microscopy.

   Daizo Hamada, Takashi Higurashi, Kouta Mayanagi, Tomoko Miyata, Takashi Fukui, Tatsuya Iida, Takeshi Honda and Itaru Yanagihara

   J Mol Biol, 365 (1), 187-195, 2007.
2. Lateral Transfer of the lux Gene Cluster.

   Sabu Kasai, Kazuhisa Okada, Akinori Hoshino, Tetsuya Iida and Takeshi Honda

   J Biochem (Tokyo), 141 (2), 231-237, 2007.
3. Polyclonality of Staphylococcus epidermidis residing on the healthy ocular surface.

   Mayumi Ueta, Tetsuya Iida, Masako Sakamoto, Chie Sotozono, Junko Takahashi, Kentaro Kojima, Kazuhisa Okada, Xiuhao Chen, Shigeru Kinoshita and Takeshi Honda

   J Med Microbiol, 56 (Pt 1), 77-82, 2007.
4. Tyrosine phosphorylation controls cortactin binding to two enterohaemorrhagic Escherichia coli effectors: Tir and EspFu/TccP.

   Vlademir V Cantarelli, Toshio Kodama, Niels Nijstad, Said Kamal Abolghait, Shigeyuki Nada, Masato Okada, Tetsuya Iida and Takeshi Honda

   Cell Microbiol, 9 (7), 1782-1795, 2007.
5. Identification and characterization of VopT, a novel ADP-ribosyltransferase effector protein secreted via the Vibrio parahaemolyticus type III secretion system 2.

   Toshio Kodama, Mitsuhiro Rokuda, Kwon-Sam Park, Vlademir V Cantarelli, Shigeaki Matsuda, Tetsuya Iida and Takeshi Honda

   Cell Microbiol, 9 (11), 2598-2609, 2007.
6. Demonstration and characterization of manganese superoxide dismutase of Providencia alcalifaciens.

   Xiuhao Chen, Toshio Kodama, Tetsuya Iida and Takeshi Honda

   Microbiol Immunol, 51 (10), 951-961, 2007.
7. Genomic diversity and homologous recombination in Vibrio parahaemolyticus as revealed by amplified fragment length polymorphism (AFLP) and multilocus sequence analysis (MLSA).

   Fabiano Thompson, Ilse Clenweerk, Jean Swings, Junko Matsuyama and Tetsuya Iida

   Microb Environ, 22, 373-379, 2007.
8. Vibrionaceae, a versatile bacterial family with evolutionarily conserved variability.

   Rikard Dryselius, Ken Kurokawa and Tetsuya Iida

   Res Microbiol, 158 (6), 479-486, 2007.

Link

http://www.biken.osaka-u.ac.jp/