Department of Cellular Regulation

Subjects:

1. Cell biological analysis on molecular mechanism of autophagy.
2. Elucidation of physiological role of autophagy.
3. Molecular dissection of endocytic pathway.

Published Papers

1. Virulence of Porphyromonas gingivalis is altered by substitution of fimbria gene with different genotype.

   Takahiro Kato, Shinji Kawai, Kazuhiko Nakano, Hiroaki Inaba, Masae Kuboniwa, Ichiro Nakagawa, Kayoko Tsuda, Hiroko Omori, Takashi Ooshima, Tamotsu Yoshimori and Atsuo Amano

   Cell Microbiol, 9 (3), 753-765, 2007.
2. The C/EBPbeta Isoform 34-kDa LAP Is Responsible for NF-IL-6-Mediated Gene Induction in Activated Macrophages, but Is Not Essential for Intracellular Bacteria Killing.

   Satoshi Uematsu, Tsuneyasu Kaisho, Takashi Tanaka, Makoto Matsumoto, Megumi Yamakami, Hiroko Omori, Masahiro Yamamoto, Tamotsu Yoshimori and Shizuo Akira

   J Immunol, 179 (8), 5378-5386, 2007.
3. Role of Hrs in maturation of autophagosomes in mammalian cells.

   Keiichi Tamai, Nobuyuki Tanaka, Atsuki Nara, Akitsugu Yamamoto, Ichiro Nakagawa, Tamotsu Yoshimori, Yoshiyuki Ueno, Tooru Shimosegawa and Kazuo Sugamura

   Biochem Biophys Res Commun, 360 (4), 721-727, 2007.
4. Linking of autophagy to ubiquitin-proteasome system is important for the regulation of endoplasmic reticulum stress and cell viability.

   Wen-Xing Ding, Hong-Min Ni, Wentao Gao, Tamotsu Yoshimori, Donna B Stolz, David Ron and Xiao-Ming Yin

   Am J Pathol, 171 (2), 513-524, 2007.
5. How to interpret LC3 immunoblotting.

   Noboru Mizushima and Tamotsu Yoshimori

   Autophagy, 3 (6), 542-545, 2007.
6. Listeria monocytogenes evades killing by autophagy during colonization of host cells.

   Cheryl L Birmingham, Veronica Canadien, Edith Gouin, Erin B Troy, Tamotsu Yoshimori, Pascale Cossart, Darren E Higgins and John H Brumell

   Autophagy, 3 (5), 442-451, 2007.
7. Maturation of fimbria precursor protein by exogenous gingipains in Porphyromonas gingivalis gingipain-null mutant.

   Takahiro Kato, Tetsuhisa Tsuda, Hiroko Omori, Takafumi Kato, Tamotsu Yoshimori and Atsuo Amano

   FEMS Microbiol Lett, 273 (1), 96-102, 2007.
8. Dissection of the Autophagosome Maturation Process by a Novel Reporter Protein, Tandem Fluorescent-Tagged LC3.

   Shunsuke Kimura, Takeshi Noda and Tamotsu Yoshimori

   Autophagy, 3 (5), 452-460, 2007.
9. Autophagy: paying Charon's toll.

   Tamotsu Yoshimori

   Cell, 128 (5), 833-836, 2007.
10. Protective role of autophagy against Vibrio cholerae cytolysin, a pore-forming toxin from V. cholerae.

    Maximiliano Gabriel Gutierrez, Hector Alex Saka, Isabel Chinen, Felipe C M Zoppino, Tamotsu Yoshimori, Jose Luis Bocco and María Isabel Colombo

    Proc Natl Acad Sci U S A, 104 (6), 1829-1834, 2007.
11. Nordihydroguaiaretic acid affects multiple dynein-dynactin functions in interphase and mitotic cells.

    Kohei Arasaki, Katsuko Tani, Tamotsu Yoshimori, David J Stephens and Mitsuo Tagaya

    Mol Pharmacol, 71 (2), 454-460, 2007.

Link

http://www.biken.osaka-u.ac.jp/