Department of Molecular Immunology

Subjects:

1. Molecular mechanisms involved in regulation of immune responses.
2. Mechanism of development of autoimmune diseases.
3. Molecular mechanism by which Epstein-Barr virus (EBV) causes B cell growth transformation and the modification of the differentiation.

Published Papers

1. CD100 enhances dendritic cell and CD4+ cell activation leading to pathogenetic humoral responses and immune complex glomerulonephritis.

   Ming Li, Kim M O'Sullivan, Lynelle K Jones, Timothy Semple, Atsushi Kumanogoh, Hitoshi Kikutani, Stephen R Holdsworth and A Richard Kitching

   J Immunol, 177 (5), 3406-3412, 2006.
2. Plexin-A1 and its interaction with DAP12 in immune responses and bone homeostasis.

   Noriko Takegahara, Hyota Takamatsu, Toshihiko Toyofuku, Tohru Tsujimura, Tatsusada Okuno, Kazunori Yukawa, Masayuki Mizui, Midori Yamamoto, Durbaka V R Prasad, Kazuhiro Suzuki, Masaru Ishii, Kenta Terai, Masayuki Moriya, Yuji Nakatsuji, Saburo Sakoda, Shintaro Sato, Shizuo Akira, Kiyoshi Takeda, Masanori Inui, Toshiyuki Takai, Masahito Ikawa, Masaru Okabe, Atsushi Kumanogoh and Hitoshi Kikutani

   Nat Cell Biol, 8 (6), 615-622, 2006.

Link

http://www.biken.osaka-u.ac.jp/