堀内班「複製フォーク阻害によって誘導される組み換え反応と遺伝子増幅」 研究代表者；堀内　嵩 分担者；小林　武彦、定塚　勝樹、篠原　彰 堀内　嵩、小林　武彦、定塚　勝樹 Kobayashi, T., Nomura, M., and Horiuchi, T. (2001) Identification of DNA cis-elements essential for expansion of ribosomal DNA repeats in Saccharomyces cerevisiae. Mol. Cell. Biol. 21, 136-147. Urawa, H., Hidaka, M., Ishiguro, S., Okada, Y., and Horiuchi, T. (2001) Enhanced homologous recombination caused by a non-transcriptional spacer of the ribosomal RNA genes in Arabidopsis. Mol. Genet. Genomics 266, 546-555 Wai, H., Johzuka, K., vu, L., Eliason, K., Kobayashi, T., Horiuchi, T., and Nomura, M. (2001) Yeast RNA polymerase enhancer is dispensable for growth and its apparent transcription enhancement form ectopic promoter requires Fob1 protein implicated in replicattion and recombination or rDNA. Mol. Cell. Biol. 21, 5541-53. Kodama, K., Kobayashi, T., Niki, H., Hiraga, S., Oshima, T., Mori, H., Horiuchi, T. (2002) Amplification of Hot DNA segments in Escherichia coli. Mol. Microbiol. 45:1575-88. . Johzuka, K., and Horiuchi, T. (2002) Replication fork block protein, Fob1, acts as an rDNA region specific recombinator in S. cerevisiae. Genes Cells 7, 99-113 Takeuchi, Y., Horiuchi, T., & Kobayashi, T. (2003) Transcription-dependent recombination and the role of fork collision in yeast rDNA. Genes Dev. 17, 1497-14506. 小林武彦、竹内　靖、定塚勝樹、堀内　嵩 (2001) ＤＮＡ複製フォークの進行阻害と遺伝子増幅 蛋白質核酸酵素　増刊号「ＤＮＡ修復ネットワークとその破綻」 46, 1004-1012. 篠原　彰 Crossover interference in Saccharomyces cerevisiae requires a TID1/RDH54- and DMC1-dependent pathway. (2003) M. Shinohara, Sakai, K., Shinohara, A. and Bishop, D.K. Genetics, 163. 1273-1286 Shinohara, M., Sakai, K., Ogawa, T., and Shinohara, A. (2003) The mitotic DNA damage checkpoint proteins Rad17 and Rad24 are required for the repair of double-strand breaks during meiosis in yeast. Genetics, 164, 855-865. 篠原　彰、篠原美紀、 染色体上でのDNA鎖交換反応-相同組換えの分子メカニズムと細胞機能　 細胞工学　22. 278-282, 2003. back