Research Center for Emerging Infectious Diseases

Subjects:

1. Studies on hepatitis C virus.
2. Development of viral vectors.
3. Development of prophylaxes and therapeutics against emerging viral infectious diseases.

Papers published in 2003

1. Effect of environmental conditions on proteins secreted by enterohemorrhagic Escherichia coli O26:H11.

   Myonsun Yoh, Zhenqing Bi, Junko Matsuyama, Kenichi Nagayama and Takeshi Honda

   Microbiol Immunol, 47 (1), 1-6, 2003.
2. Sumoylation is involved in beta-catenin-dependent activation of Tcf-4.

   Hideki Yamamoto, Motomasa Ihara, Yoshiharu Matsuura and Akira Kikuchi

   EMBO J, 22 (9), 2047-2059, 2003.
3. Immunization with recombinant Calmette-Guerin bacillus (BCG)-hepatitis C virus (HCV) elicits HCV-specific cytotoxic T lymphocytes in mice.

   Satori Uno-Furuta, Kazuhiro Matsuo, Shigenori Tamaki, Shiki Takamura, Akira Kamei, Isao Kuromatsu, Masahiko Kaito, Yoshiharu Matsuura, Tatsuo Miyamura, Yukihiko Adachi and Yasuhiro Yasutomi

   Vaccine, 21 (23), 3149-3156, 2003.
4. Spontaneous elimination of serum hepatitis C virus (HCV) RNA in chronic HCV carriers: a population-based cohort study.

   Hisayoshi Watanabe, Takafumi Saito, Haruhide Shinzawa, Kazuo Okumoto, Etsuko Hattori, Tohru Adachi, Tadashi Takeda, Kazuhiko Sugahara, Jun-itsu Ito, Koji Saito, Hitoshi Togashi, Ryosuke Suzuki, Masahiro Hayashi, Tatsuo Miyamura, Yoshiharu Matsuura and Sumio Kawata

   J Med Virol, 71 (1), 56-61, 2003.
5. Baculovirus induces an innate immune response and confers protection from lethal influenza virus infection in mice.

   Takayuki Abe, Hitoshi Takahashi, Hiroyuki Hamazaki, Naoko Miyano-Kurosaki, Yoshiharu Matsuura and Hiroshi Takaku

   J Immunol, 171 (3), 1133-1139, 2003.
6. In vitro and in vivo gene delivery by recombinant baculoviruses.

   Hideki Tani, Chang Kwang Limn, Chan Choo Yap, Masayoshi Onishi, Masami Nozaki, Yoshitake Nishimune, Nobuo Okahashi, Yoshinori Kitagawa, Rie Watanabe, Rika Mochizuki, Kohji Moriishi and Yoshiharu Matsuura

   J Virol, 77 (18), 9799-9808, 2003.
7. CRMP-2 regulates polarized Numb-mediated endocytosis for axon growth.

   Takashi Nishimura, Yuko Fukata, Katsuhiro Kato, Tomoya Yamaguchi, Yoshiharu Matsuura, Hiroyuki Kamiguchi and Kozo Kaibuchi

   Nat Cell Biol, 5 (9), 819-826, 2003.
8. Proteasome activator PA28gamma-dependent nuclear retention and degradation of hepatitis C virus core protein.

   Kohji Moriishi, Tamaki Okabayashi, Kousuke Nakai, Kyoji Moriya, Kazuhiko Koike, Shigeo Murata, Tomoki Chiba, Keiji Tanaka, Ryosuke Suzuki, Tetsuro Suzuki, Tatsuo Miyamura and Yoshiharu Matsuura

   J Virol, 77 (19), 10237-10249, 2003.
9. Hepatitis C virus core protein activates ERK and p38 MAPK in cooperation with ethanol in transgenic mice.

   Takeya Tsutsumi, Tetsuro Suzuki, Kyoji Moriya, Yoshizumi Shintani, Hajime Fujie, Hideyuki Miyoshi, Yoshiharu Matsuura, Kazuhiko Koike and Tatsuo Miyamura

   Hepatology, 38 (4), 820-828, 2003.
10. Production and release of infectious hepatitis C virus from human liver cell cultures in the three-dimensional radial-flow bioreactor.

    Hideki Aizaki, Seishi Nagamori, Mami Matsuda, Hayato Kawakami, Osamu Hashimoto, Hiroaki Ishiko, Masaaki Kawada, Tomokazu Matsuura, Satoshi Hasumura, Yoshiharu Matsuura, Tetsuro Suzuki and Tatsuo Miyamura

    Virology, 314 (1), 16-25, 2003.
11. Antiapoptotic regulation by hepatitis C virus core protein through up-regulation of inhibitor of caspase-activated DNase.

    Rodolfo Sacco, Takeya Tsutsumi, Ryosuke Suzuki, Motoyuki Otsuka, Hideki Aizaki, Shinichiro Sakamoto, Mami Matsuda, Naohiko Seki, Yoshiharu Matsuura, Tatsuo Miyamura and Tetsuro Suzuki

    Virology, 317 (1), 24-35, 2003.
12. Sensitivity to human serum of gammaretroviruses produced from pig endothelial cells transduced with glycosyltransferase genes.

    Takashi Kurihara, Takayuki Miyazawa, Shuji Miyagawa, Keizo Tomonaga, Kenji Hazama, Junko Yamada, Ryota Shirakura and Yoshiharu Matsuura

    Xenotransplantation, 10 (6), 562-568, 2003.
13. Mechanisms of hepatitis C virus infection.

    Kohji Moriishi and Yoshiharu Matsuura

    Antivir Chem Chemother, 14 (6), 285-297, 2003.

Link

http://www.biken.osaka-u.ac.jp/