Arisue N, Hirai M, Arai M, Matsuoka H, Horii T.
Phylogeny and Evolution of the SERA Multigene Family in the Genus Plasmodium.
J Mol Evol. 2007 Jul;65(1):82-91. PMID: 17609844
Tanabe K, Sakihama N, Walliker D, Babiker H, Abdel-Muhsin AM, Bakote'e B, Ohmae H, Arisue N, Horii T, Rooth I, Farnert A, Bjorkman A, Ranford-Cartwright L.
Allelic dimorphism-associated restriction of recombination in Plasmodium falciparum msp1.
Gene. 2007 Aug 1;397(1-2):153-60. PMID: 17574779
Cheng XJ, Hayasaka H, Watanabe K, Tao YL, Liu JY, Tsukamoto H, Horii T, Tanabe K, Tachibana H.
Production of high-affinity human monoclonal antibody fab fragments to the 19-kilodalton C-terminal merozoite surface protein 1 of Plasmodium falciparum.
Infect Immun. 2007 Jul;75(7):3614-20. PMID: 17452466
Coban C, Ishii KJ, Horii T, Akira S.
Manipulation of host innate immune responses by the malaria parasite.
Trends Microbiol. 2007 Jun;15(6):271-8. PMID: 17466521
Kimata-Ariga Y, Kurisu G, Kusunoki M, Aoki S, Sato D, Kobayashi T, Kita K, Horii T, Hase T.
Cloning and characterization of ferredoxin and ferredoxin-NADP+ reductase from human malaria parasite.
J Biochem (Tokyo). 2007 Mar;141(3):421-8. PMID: 17251200
Coban C, Ishii KJ, Uematsu S, Arisue N, Sato S, Yamamoto M, Kawai T, Takeuchi O, Hisaeda H, Horii T, Akira S.
Pathological role of Toll-like receptor signaling in cerebral malaria.
Int Immunol. 2007 Jan;19(1):67-79. PMID: 17135446
Palacpac NM, Leung BW, Arisue N, Tanabe K, Sattabongkot J, Tsuboi T, Torii M, Udomsangpetch R, Horii T.
Plasmodium vivax serine repeat antigen (SERA) multigene family exhibits similar expression patterns in independent infections.
Mol Biochem Parasitol. 2006 Dec;150(2):353-8. PMID: 16934884
Krungkrai SR, Tokuoka K, Kusakari Y, Inoue T, Adachi H, Matsumura H, Takano K, Murakami S, Mori Y, Kai Y, Krungkrai J, Horii T.
Crystallization and preliminary crystallographic analysis of orotidine 5'-monophosphate decarboxylase from the human malaria parasite Plasmodium falciparum.
Acta Crystallograph Sect F Struct Biol Cryst Commun. 2006 Jun 1;62(Pt 6):542-5. PMID: 16754976
Okech B, Mujuzi G, Ogwal A, Shirai H, Horii T, Egwang TG.
High titers of IgG antibodies against Plasmodium falciparum serine repeat antigen 5 (SERA5) are associated with protection against severe malaria in Ugandan children.
Am J Trop Med Hyg. 2006 Feb;74(2):191-7 PMID: 16474069
Sato D, Li J, Mitamura T, Horii T.
Plasmodium falciparum serine-repeat antigen (SERA) forms a homodimer through disulfide bond.
Parasitol Int. 2005 Dec;54(4):261-5. PMID: 16048741
Krungkrai SR, DelFraino BJ, Smiley JA, Prapunwattana P, Mitamura T, Horii T, Krungkrai J.
A novel enzyme complex of orotate phosphoribosyltransferase and orotidine 5'-monophosphate decarboxylase in human malaria parasite Plasmodium falciparum: physical association, kinetics, and inhibition characterization.
Biochemistry. 2005 Feb 8;44(5):1643-52. PMID: 15683248
Coban C, Ishii KJ, Kawai T, Hemmi H, Sato S, Uematsu S, Yamamoto M, Takeuchi O, Itagaki S, Kumar N, Horii T, Akira S.
Toll-like receptor 9 mediates innate immune activation by the malaria pigment hemozoin.
J Exp Med. 2005 Jan 3;201(1):19-25. PMID: 15630134
Kawanishi M, Kotoku N, Itagaki S, Horii T, Kobayashi M.
Structure-activity relationship of anti-malarial spongean peroxides having a 3-methoxy-1,2-dioxane structure.
Bioorg Med Chem. 2004 Oct 15;12(20):5297-307. PMID: 15388157
Palacpac NM, Hiramine Y, Seto S, Hiramatsu R, Horii T, Mitamura T.
Evidence that Plasmodium falciparum diacylglycerol acyltransferase is essential for intraerythrocytic proliferation.
Biochem Biophys Res Commun. 2004 Sep 3;321(4):1062-8. PMID: 15358136
Krungkrai SR, Prapunwattana P, Horii T, Krungkrai J.
Orotate phosphoribosyltransferase and orotidine 5'-monophosphate decarboxylase exist as multienzyme complex in human malaria parasite Plasmodium falciparum.
Biochem Biophys Res Commun. 2004 Jun 11;318(4):1012-8. PMID: 15147974
Krungkrai SR, Aoki S, Palacpac NM, Sato D, Mitamura T, Krungkrai J, Horii T.
Human malaria parasite orotate phosphoribosyltransferase: functional expression, characterization of kinetic reaction mechanism and inhibition profile.
Mol Biochem Parasitol. 2004 Apr;134(2):245-55. PMID: 15003844
Sakihama N, Matsuo T, Mitamura T, Horii T, Kimura M, Kawabata M, Tanabe K.
Relative frequencies of polymorphisms of variation in Block 2 repeats and 5' recombinant types of Plasmodium falciparum msp1 alleles.
Parasitol Int. 2004 Mar;53(1):59-67. PMID: 14984836
Murakami N, Kawanishi M, Mostaqul HM, Li J, Itagaki S, Horii T, Kobayashi M.
New anti-malarial peroxides with in vivo potency derived from spongean metabolites.
Bioorg Med Chem Lett. 2003 Nov 17;13(22):4081-4. PMID: 14592512
Safitri I, Jalloh A, Tantular IS, Pusarawati S, Win TT, Liu Q, Ferreira MU, Dachlan YP, Horii T, Kawamoto F.
Sequence diversity in the amino-terminal region of the malaria-vaccine candidate serine repeat antigen in natural Plasmodium falciparum populations.
Parasitol Int. 2003 Jun;52(2):117-31. PMID: 12798923
Soe S, Singh S, Camus D, Horii T, Druilhe P.
Plasmodium falciparum serine repeat protein, a new target of monocyte-dependent antibody-mediated parasite killing.
Infect Immun. 2002 Dec;70(12):7182-4. PMID: 12438408
Aoki S, Li J, Itagaki S, Okech BA, Egwang TG, Matsuoka H, Palacpac NM, Mitamura T, Horii T.
Serine repeat antigen (SERA5) is predominantly expressed among the SERA multigene family of Plasmodium falciparum, and the acquired antibody titers correlate with serum inhibition of the parasite growth.
J Biol Chem. 2002 Dec 6;277(49):47533-40. PMID: 12244052
Li J, Mitamura T, Fox BA, Bzik DJ, Horii T.
Differential localization of processed fragments of Plasmodium falciparum serine repeat antigen and further processing of its N-terminal 47 kDa fragment.
Parasitol Int. 2002 Dec;51(4):343-52. PMID: 12421632
Fox BA, Horii T, Bzik DJ.
Plasmodium falciparum: fine-mapping of an epitope of the serine repeat antigen that is a target of parasite-inhibitory antibodies.
Exp Parasitol. 2002 May;101(1):69-72. PMID: 12243740
Li J, Matsuoka H, Mitamura T, Horii T.
Characterization of proteases involved in the processing of Plasmodium falciparum serine repeat antigen (SERA).
Mol Biochem Parasitol. 2002 Apr 9;120(2):177-86. PMID: 11897123
Hanada K, Palacpac NM, Magistrado PA, Kurokawa K, Rai G, Sakata D, Hara T, Horii T, Nishijima M, Mitamura T.
Plasmodium falciparum phospholipase C hydrolyzing sphingomyelin and lysocholinephospholipids is a possible target for malaria chemotherapy.
J Exp Med. 2002 Jan 7;195(1):23-34. PMID: 11781362
Okech BA, Nalunkuma A, Okello D, Pang XL, Suzue K, Li J, Horii T, Egwang TG.
Natural human immunoglobulin G subclass responses to Plasmodium falciparum serine repeat antigen in Uganda.
Am J Trop Med Hyg. 2001 Dec;65(6):912-7. PMID: 11791998
Murakami N, Mostaqul HM, Tamura S, Itagaki S, Horii T, Kobayashi M.
New anti-malarial flavonol glycoside from Hydrangeae Dulcis Folium.
Bioorg Med Chem Lett. 2001 Sep 17;11(18):2445-7. PMID: 11549443
Sakihama N, Mitamura T, Kaneko A, Horii T, Tanabe K.
Long PCR amplification of Plasmodium falciparum DNA extracted from filter paper blots.
Exp Parasitol. 2001 Jan;97(1):50-4. No abstract available. PMID: 11207114
Liu Q, Ferreira MU, Ndawi BT, Ohmae H, Adagu IS, Morikawa T, Horii T, Isomura S, Kawamoto F.
Sequence diversity of serine repeat antigen gene exon II of Plasmodium falciparum in worldwide collected wild isolates.
Southeast Asian J Trop Med Public Health. 2000 Dec;31(4):808-17. PMID: 1141443
Hayashi M, Yamada H, Mitamura T, Horii T, Yamamoto A, Moriyama Y.
Vacuolar H(+)-ATPase localized in plasma membranes of malaria parasite cells, Plasmodium falciparum, is involved in regional acidification of parasitized erythrocytes.
J Biol Chem. 2000 Nov 3;275(44):34353-8. PMID: 10915784
Mitamura T, Hanada K, Ko-Mitamura EP, Nishijima M, Horii T.
Serum factors governing intraerythrocytic development and cell cycle progression of Plasmodium falciparum.
Parasitol Int. 2000 Sep;49(3):219-29. PMID: 11426577
Hanada K, Mitamura T, Fukasawa M, Magistrado PA, Horii T, Nishijima M.
Neutral sphingomyelinase activity dependent on Mg2+ and anionic phospholipids in the intraerythrocytic malaria parasite Plasmodium falciparum.
Biochem J. 2000 Mar 15;346 Pt 3:671-7. PMID: 10698693
Belperron AA, Feltquate D, Fox BA, Horii T, Bzik DJ.
Immune responses induced by gene gun or intramuscular injection of DNA vaccines that express immunogenic regions of the serine repeat antigen from Plasmodium falciparum.
Infect Immun. 1999 Oct;67(10):5163-9. PMID: 10496891
Wang P, Brobey RK, Horii T, Sims PF, Hyde JE.
Utilization of exogenous folate in the human malaria parasite Plasmodium falciparum and its critical role in antifolate drug synergy.
Mol Microbiol. 1999 Jun;32(6):1254-62. PMID: 10383765
Kim HS, Hayashi M, Shibata Y, Wataya Y, Mitamura T, Horii T, Kawauchi K, Hirata H, Tsuboi S, Moriyama Y.
Cycloprodigiosin hydrochloride obtained from Pseudoalteromonas denitrificans is a potent antimalarial agent.
Biol Pharm Bull. 1999 May;22(5):532-4. PMID: 10375177
Pang XL, Mitamura T, Horii T.
Antibodies reactive with the N-terminal domain of Plasmodium falciparum serine repeat antigen inhibit cell proliferation by agglutinating merozoites and schizonts.
Infect Immun. 1999 Apr;67(4):1821-7. PMID: 10085023
Sakai T, Horii T, Hisaeda H, Zhang M, Ishii K, Nakano Y, Maekawa Y, Izumi K, Nitta Y, Miyazaki J, Himeno K.
DNA immunization with Plasmodium falciparum serine repeat antigen: regulation of humoral immune response by coinoculation of cytokine expression plasmid.
Parasitol Int. 1999 Mar;48(1):27-33. PMID: 11269323
Kilunga Kubata B, Eguchi N, Urade Y, Yamashita K, Mitamura T, Tai K, Hayaishi O, Horii T.
Plasmodium falciparum produces prostaglandins that are pyrogenic, somnogenic, and immunosuppressive substances in humans.
J Exp Med. 1998 Sep 21;188(6):1197-202. PMID: 9743538
Pang XL, Horii T.
Complement-mediated killing of Plasmodium falciparum erythrocytic schizont with antibodies to the recombinant serine repeat antigen (SERA).
Vaccine. 1998 Aug;16(13):1299-305. PMID: 9682394
Morimatsu K, Morikawa T, Tanabe K, Bzik DJ, Horii T.
Sequence diversity in the amino-terminal 47 kDa fragment of the Plasmodium falciparum serine repeat antigen.
Mol Biochem Parasitol. 1997 Jun;86(2):249-54. PMID: 9200130
Toyoda T, Brobey RK, Sano G, Horii T, Tomioka N, Itai A.
Lead discovery of inhibitors of the dihydrofolate reductase domain of Plasmodium falciparum dihydrofolate reductase-thymidylate synthase.
Biochem Biophys Res Commun. 1997 Jun 27;235(3):515-9. PMID: 9207187
Fox BA, Xing-Li P, Suzue K, Horii T, Bzik DJ.
Plasmodium falciparum: an epitope within a highly conserved region of the 47-kDa amino-terminal domain of the serine repeat antigen is a target of parasite-inhibitory antibodies.
Exp Parasitol. 1997 Feb;85(2):121-34. PMID: 9030663
Brobey RK, Sano G, Itoh F, Aso K, Kimura M, Mitamura T, Horii T.
Recombinant Plasmodium falciparum dihydrofolate reductase-based in vitro screen for antifolate antimalarials.
Mol Biochem Parasitol. 1996 Oct 30;81(2):225-37. PMID: 8898337
Sugiyama T, Suzue K, Okamoto M, Inselburg J, Tai K, Horii T.
Production of recombinant SERA proteins of Plasmodium falciparum in Escherichia coli by using synthetic genes.
Vaccine. 1996 Aug;14(11):1069-76. PMID: 8879104
Sano G, Morimatsu K, Horii T.
Purification and characterization of dihydrofolate reductase of Plasmodium falciparum expressed by a synthetic gene in Escherichia coli.
Mol Biochem Parasitol. 1994 Feb;63(2):265-73. PMID: 8008023
Li WB, Bzik DJ, Horii T, Inselburg J
. Structure and expression of the Plasmodium falciparum SERA gene.
Mol Biochem Parasitol. 1989 Feb;33(1):13-25. PMID: 2651911
Bzik DJ, Li WB, Horii T, Inselburg J.
Amino acid sequence of the serine-repeat antigen (SERA) of Plasmodium falciparum determined from cloned cDNA.
Mol Biochem Parasitol. 1988 Sep;30(3):279-88. PMID: 2847041
Horii T, Bzik DJ, Inselburg J
. Characterization of antigen-expressing Plasmodium falciparum cDNA clones that are reactive with parasite inhibitory antibodies.
Mol Biochem Parasitol. 1988 Jul;30(1):9-18. PMID: 2456465
Inselburg J, Bzik DJ, Horii T.
Pyrimethamine resistant Plasmodium falciparum: overproduction of dihydrofolate reductase by a gene duplication.
Mol Biochem Parasitol. 1987 Nov;26(1-2):121-34. PMID: 3323903
Phylogeny and Evolution of the SERA Multigene Family in the Genus Plasmodium.
J Mol Evol. 2007 Jul;65(1):82-91. PMID: 17609844
Tanabe K, Sakihama N, Walliker D, Babiker H, Abdel-Muhsin AM, Bakote'e B, Ohmae H, Arisue N, Horii T, Rooth I, Farnert A, Bjorkman A, Ranford-Cartwright L.
Allelic dimorphism-associated restriction of recombination in Plasmodium falciparum msp1.
Gene. 2007 Aug 1;397(1-2):153-60. PMID: 17574779
Cheng XJ, Hayasaka H, Watanabe K, Tao YL, Liu JY, Tsukamoto H, Horii T, Tanabe K, Tachibana H.
Production of high-affinity human monoclonal antibody fab fragments to the 19-kilodalton C-terminal merozoite surface protein 1 of Plasmodium falciparum.
Infect Immun. 2007 Jul;75(7):3614-20. PMID: 17452466
Coban C, Ishii KJ, Horii T, Akira S.
Manipulation of host innate immune responses by the malaria parasite.
Trends Microbiol. 2007 Jun;15(6):271-8. PMID: 17466521
Kimata-Ariga Y, Kurisu G, Kusunoki M, Aoki S, Sato D, Kobayashi T, Kita K, Horii T, Hase T.
Cloning and characterization of ferredoxin and ferredoxin-NADP+ reductase from human malaria parasite.
J Biochem (Tokyo). 2007 Mar;141(3):421-8. PMID: 17251200
Coban C, Ishii KJ, Uematsu S, Arisue N, Sato S, Yamamoto M, Kawai T, Takeuchi O, Hisaeda H, Horii T, Akira S.
Pathological role of Toll-like receptor signaling in cerebral malaria.
Int Immunol. 2007 Jan;19(1):67-79. PMID: 17135446
Palacpac NM, Leung BW, Arisue N, Tanabe K, Sattabongkot J, Tsuboi T, Torii M, Udomsangpetch R, Horii T.
Plasmodium vivax serine repeat antigen (SERA) multigene family exhibits similar expression patterns in independent infections.
Mol Biochem Parasitol. 2006 Dec;150(2):353-8. PMID: 16934884
Krungkrai SR, Tokuoka K, Kusakari Y, Inoue T, Adachi H, Matsumura H, Takano K, Murakami S, Mori Y, Kai Y, Krungkrai J, Horii T.
Crystallization and preliminary crystallographic analysis of orotidine 5'-monophosphate decarboxylase from the human malaria parasite Plasmodium falciparum.
Acta Crystallograph Sect F Struct Biol Cryst Commun. 2006 Jun 1;62(Pt 6):542-5. PMID: 16754976
Okech B, Mujuzi G, Ogwal A, Shirai H, Horii T, Egwang TG.
High titers of IgG antibodies against Plasmodium falciparum serine repeat antigen 5 (SERA5) are associated with protection against severe malaria in Ugandan children.
Am J Trop Med Hyg. 2006 Feb;74(2):191-7 PMID: 16474069
Sato D, Li J, Mitamura T, Horii T.
Plasmodium falciparum serine-repeat antigen (SERA) forms a homodimer through disulfide bond.
Parasitol Int. 2005 Dec;54(4):261-5. PMID: 16048741
Krungkrai SR, DelFraino BJ, Smiley JA, Prapunwattana P, Mitamura T, Horii T, Krungkrai J.
A novel enzyme complex of orotate phosphoribosyltransferase and orotidine 5'-monophosphate decarboxylase in human malaria parasite Plasmodium falciparum: physical association, kinetics, and inhibition characterization.
Biochemistry. 2005 Feb 8;44(5):1643-52. PMID: 15683248
Coban C, Ishii KJ, Kawai T, Hemmi H, Sato S, Uematsu S, Yamamoto M, Takeuchi O, Itagaki S, Kumar N, Horii T, Akira S.
Toll-like receptor 9 mediates innate immune activation by the malaria pigment hemozoin.
J Exp Med. 2005 Jan 3;201(1):19-25. PMID: 15630134
Kawanishi M, Kotoku N, Itagaki S, Horii T, Kobayashi M.
Structure-activity relationship of anti-malarial spongean peroxides having a 3-methoxy-1,2-dioxane structure.
Bioorg Med Chem. 2004 Oct 15;12(20):5297-307. PMID: 15388157
Palacpac NM, Hiramine Y, Seto S, Hiramatsu R, Horii T, Mitamura T.
Evidence that Plasmodium falciparum diacylglycerol acyltransferase is essential for intraerythrocytic proliferation.
Biochem Biophys Res Commun. 2004 Sep 3;321(4):1062-8. PMID: 15358136
Krungkrai SR, Prapunwattana P, Horii T, Krungkrai J.
Orotate phosphoribosyltransferase and orotidine 5'-monophosphate decarboxylase exist as multienzyme complex in human malaria parasite Plasmodium falciparum.
Biochem Biophys Res Commun. 2004 Jun 11;318(4):1012-8. PMID: 15147974
Krungkrai SR, Aoki S, Palacpac NM, Sato D, Mitamura T, Krungkrai J, Horii T.
Human malaria parasite orotate phosphoribosyltransferase: functional expression, characterization of kinetic reaction mechanism and inhibition profile.
Mol Biochem Parasitol. 2004 Apr;134(2):245-55. PMID: 15003844
Sakihama N, Matsuo T, Mitamura T, Horii T, Kimura M, Kawabata M, Tanabe K.
Relative frequencies of polymorphisms of variation in Block 2 repeats and 5' recombinant types of Plasmodium falciparum msp1 alleles.
Parasitol Int. 2004 Mar;53(1):59-67. PMID: 14984836
Murakami N, Kawanishi M, Mostaqul HM, Li J, Itagaki S, Horii T, Kobayashi M.
New anti-malarial peroxides with in vivo potency derived from spongean metabolites.
Bioorg Med Chem Lett. 2003 Nov 17;13(22):4081-4. PMID: 14592512
Safitri I, Jalloh A, Tantular IS, Pusarawati S, Win TT, Liu Q, Ferreira MU, Dachlan YP, Horii T, Kawamoto F.
Sequence diversity in the amino-terminal region of the malaria-vaccine candidate serine repeat antigen in natural Plasmodium falciparum populations.
Parasitol Int. 2003 Jun;52(2):117-31. PMID: 12798923
Soe S, Singh S, Camus D, Horii T, Druilhe P.
Plasmodium falciparum serine repeat protein, a new target of monocyte-dependent antibody-mediated parasite killing.
Infect Immun. 2002 Dec;70(12):7182-4. PMID: 12438408
Aoki S, Li J, Itagaki S, Okech BA, Egwang TG, Matsuoka H, Palacpac NM, Mitamura T, Horii T.
Serine repeat antigen (SERA5) is predominantly expressed among the SERA multigene family of Plasmodium falciparum, and the acquired antibody titers correlate with serum inhibition of the parasite growth.
J Biol Chem. 2002 Dec 6;277(49):47533-40. PMID: 12244052
Li J, Mitamura T, Fox BA, Bzik DJ, Horii T.
Differential localization of processed fragments of Plasmodium falciparum serine repeat antigen and further processing of its N-terminal 47 kDa fragment.
Parasitol Int. 2002 Dec;51(4):343-52. PMID: 12421632
Fox BA, Horii T, Bzik DJ.
Plasmodium falciparum: fine-mapping of an epitope of the serine repeat antigen that is a target of parasite-inhibitory antibodies.
Exp Parasitol. 2002 May;101(1):69-72. PMID: 12243740
Li J, Matsuoka H, Mitamura T, Horii T.
Characterization of proteases involved in the processing of Plasmodium falciparum serine repeat antigen (SERA).
Mol Biochem Parasitol. 2002 Apr 9;120(2):177-86. PMID: 11897123
Hanada K, Palacpac NM, Magistrado PA, Kurokawa K, Rai G, Sakata D, Hara T, Horii T, Nishijima M, Mitamura T.
Plasmodium falciparum phospholipase C hydrolyzing sphingomyelin and lysocholinephospholipids is a possible target for malaria chemotherapy.
J Exp Med. 2002 Jan 7;195(1):23-34. PMID: 11781362
Okech BA, Nalunkuma A, Okello D, Pang XL, Suzue K, Li J, Horii T, Egwang TG.
Natural human immunoglobulin G subclass responses to Plasmodium falciparum serine repeat antigen in Uganda.
Am J Trop Med Hyg. 2001 Dec;65(6):912-7. PMID: 11791998
Murakami N, Mostaqul HM, Tamura S, Itagaki S, Horii T, Kobayashi M.
New anti-malarial flavonol glycoside from Hydrangeae Dulcis Folium.
Bioorg Med Chem Lett. 2001 Sep 17;11(18):2445-7. PMID: 11549443
Sakihama N, Mitamura T, Kaneko A, Horii T, Tanabe K.
Long PCR amplification of Plasmodium falciparum DNA extracted from filter paper blots.
Exp Parasitol. 2001 Jan;97(1):50-4. No abstract available. PMID: 11207114
Liu Q, Ferreira MU, Ndawi BT, Ohmae H, Adagu IS, Morikawa T, Horii T, Isomura S, Kawamoto F.
Sequence diversity of serine repeat antigen gene exon II of Plasmodium falciparum in worldwide collected wild isolates.
Southeast Asian J Trop Med Public Health. 2000 Dec;31(4):808-17. PMID: 1141443
Hayashi M, Yamada H, Mitamura T, Horii T, Yamamoto A, Moriyama Y.
Vacuolar H(+)-ATPase localized in plasma membranes of malaria parasite cells, Plasmodium falciparum, is involved in regional acidification of parasitized erythrocytes.
J Biol Chem. 2000 Nov 3;275(44):34353-8. PMID: 10915784
Mitamura T, Hanada K, Ko-Mitamura EP, Nishijima M, Horii T.
Serum factors governing intraerythrocytic development and cell cycle progression of Plasmodium falciparum.
Parasitol Int. 2000 Sep;49(3):219-29. PMID: 11426577
Hanada K, Mitamura T, Fukasawa M, Magistrado PA, Horii T, Nishijima M.
Neutral sphingomyelinase activity dependent on Mg2+ and anionic phospholipids in the intraerythrocytic malaria parasite Plasmodium falciparum.
Biochem J. 2000 Mar 15;346 Pt 3:671-7. PMID: 10698693
Belperron AA, Feltquate D, Fox BA, Horii T, Bzik DJ.
Immune responses induced by gene gun or intramuscular injection of DNA vaccines that express immunogenic regions of the serine repeat antigen from Plasmodium falciparum.
Infect Immun. 1999 Oct;67(10):5163-9. PMID: 10496891
Wang P, Brobey RK, Horii T, Sims PF, Hyde JE.
Utilization of exogenous folate in the human malaria parasite Plasmodium falciparum and its critical role in antifolate drug synergy.
Mol Microbiol. 1999 Jun;32(6):1254-62. PMID: 10383765
Kim HS, Hayashi M, Shibata Y, Wataya Y, Mitamura T, Horii T, Kawauchi K, Hirata H, Tsuboi S, Moriyama Y.
Cycloprodigiosin hydrochloride obtained from Pseudoalteromonas denitrificans is a potent antimalarial agent.
Biol Pharm Bull. 1999 May;22(5):532-4. PMID: 10375177
Pang XL, Mitamura T, Horii T.
Antibodies reactive with the N-terminal domain of Plasmodium falciparum serine repeat antigen inhibit cell proliferation by agglutinating merozoites and schizonts.
Infect Immun. 1999 Apr;67(4):1821-7. PMID: 10085023
Sakai T, Horii T, Hisaeda H, Zhang M, Ishii K, Nakano Y, Maekawa Y, Izumi K, Nitta Y, Miyazaki J, Himeno K.
DNA immunization with Plasmodium falciparum serine repeat antigen: regulation of humoral immune response by coinoculation of cytokine expression plasmid.
Parasitol Int. 1999 Mar;48(1):27-33. PMID: 11269323
Kilunga Kubata B, Eguchi N, Urade Y, Yamashita K, Mitamura T, Tai K, Hayaishi O, Horii T.
Plasmodium falciparum produces prostaglandins that are pyrogenic, somnogenic, and immunosuppressive substances in humans.
J Exp Med. 1998 Sep 21;188(6):1197-202. PMID: 9743538
Pang XL, Horii T.
Complement-mediated killing of Plasmodium falciparum erythrocytic schizont with antibodies to the recombinant serine repeat antigen (SERA).
Vaccine. 1998 Aug;16(13):1299-305. PMID: 9682394
Morimatsu K, Morikawa T, Tanabe K, Bzik DJ, Horii T.
Sequence diversity in the amino-terminal 47 kDa fragment of the Plasmodium falciparum serine repeat antigen.
Mol Biochem Parasitol. 1997 Jun;86(2):249-54. PMID: 9200130
Toyoda T, Brobey RK, Sano G, Horii T, Tomioka N, Itai A.
Lead discovery of inhibitors of the dihydrofolate reductase domain of Plasmodium falciparum dihydrofolate reductase-thymidylate synthase.
Biochem Biophys Res Commun. 1997 Jun 27;235(3):515-9. PMID: 9207187
Fox BA, Xing-Li P, Suzue K, Horii T, Bzik DJ.
Plasmodium falciparum: an epitope within a highly conserved region of the 47-kDa amino-terminal domain of the serine repeat antigen is a target of parasite-inhibitory antibodies.
Exp Parasitol. 1997 Feb;85(2):121-34. PMID: 9030663
Brobey RK, Sano G, Itoh F, Aso K, Kimura M, Mitamura T, Horii T.
Recombinant Plasmodium falciparum dihydrofolate reductase-based in vitro screen for antifolate antimalarials.
Mol Biochem Parasitol. 1996 Oct 30;81(2):225-37. PMID: 8898337
Sugiyama T, Suzue K, Okamoto M, Inselburg J, Tai K, Horii T.
Production of recombinant SERA proteins of Plasmodium falciparum in Escherichia coli by using synthetic genes.
Vaccine. 1996 Aug;14(11):1069-76. PMID: 8879104
Sano G, Morimatsu K, Horii T.
Purification and characterization of dihydrofolate reductase of Plasmodium falciparum expressed by a synthetic gene in Escherichia coli.
Mol Biochem Parasitol. 1994 Feb;63(2):265-73. PMID: 8008023
Li WB, Bzik DJ, Horii T, Inselburg J
. Structure and expression of the Plasmodium falciparum SERA gene.
Mol Biochem Parasitol. 1989 Feb;33(1):13-25. PMID: 2651911
Bzik DJ, Li WB, Horii T, Inselburg J.
Amino acid sequence of the serine-repeat antigen (SERA) of Plasmodium falciparum determined from cloned cDNA.
Mol Biochem Parasitol. 1988 Sep;30(3):279-88. PMID: 2847041
Horii T, Bzik DJ, Inselburg J
. Characterization of antigen-expressing Plasmodium falciparum cDNA clones that are reactive with parasite inhibitory antibodies.
Mol Biochem Parasitol. 1988 Jul;30(1):9-18. PMID: 2456465
Inselburg J, Bzik DJ, Horii T.
Pyrimethamine resistant Plasmodium falciparum: overproduction of dihydrofolate reductase by a gene duplication.
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