papers

Recent Publications (2000-)

英文原著

2010-
Sakuragi JI, Ode H, Sakuragi S, Shioda T, Sato H. A proposal for a new HIV-1 DLS structural model. Nucleic Acids Res. 2012 Feb 10. [Epub ahead of print]

Nakayama EE, Shioda T. TRIM5α and Species Tropism of HIV/SIV. Front Microbiol. 2012;3:13. Review. Epub 2012 Jan 24.

Sakuragi J. Morphogenesis of the Infectious HIV-1 Virion. Front Microbiol. 2011;2:242. Review. Epub 2011 Dec 9.

Saito A, Kono K, Nomaguchi M, Yasutomi Y, Adachi A, Shioda T, Akari H, Nakayama EE. Geographical, genetic and functional diversity of antiretroviral host factor TRIMCyp in cynomolgus macaque (Macaca fascicularis). J Gen Virol. 2012 Mar;93(Pt 3):594-602. Epub 2011 Nov 23.

Miyamoto T, Yokoyama M, Kono K, Shioda T, Sato H, Nakayama EE. A single amino acid of human immunodeficiency virus type 2 capsid protein affects conformation of two external loops and viral sensitivity to TRIM5α. PLoS One. 2011;6(7):e22779. Epub 2011 Jul 28.

Ohishi M, Nakano T, Sakuragi S, Shioda T, Sano K, Sakuragi J. The relationship between HIV-1 genome RNA dimerization, virion maturation and infectivity. Nucleic Acids Res. 2011 Apr;39(8):3404-17. Epub 2010 Dec 23.

Saito A, Nomaguchi M, Iijima S, Kuroishi A, Yoshida T, Lee YJ, Hayakawa T, Kono K, Nakayama EE, Shioda T, Yasutomi Y, Adachi A, Matano T, Akari H. Improved capacity of a monkey-tropic HIV-1 derivative to replicate in cynomolgus monkeys with minimal modifications. Microbes Infect. 2011 Jan;13(1):58-64. Epub 2010 Oct 16.

Kono K, Song H, Yokoyama M, Sato H, Shioda T, Nakayama EE. Multiple sites in the N-terminal half of simian immunodeficiency virus capsid protein contribute to evasion from rhesus monkey TRIM5α-mediated restriction. Retrovirology. 2010 Sep 8;7:72.

Sakuragi J, Sakuragi S, Ohishi M, Shioda T. Direct correlation between genome dimerization and recombination efficiency of HIV-1. Microbes Infect. 2010 Nov;12(12-13):1002-11. Epub 2010 Jul 15.

Kuroishi A, Bozek K, Shioda T, Nakayama EE. A single amino acid substitution of the human immunodeficiency virus type 1 capsid protein affects viral sensitivity to TRIM5 alpha. Retrovirology. 2010 Jul 7;7:58.

Onyango CO, Leligdowicz A, Yokoyama M, Sato H, Song H, Nakayama EE, Shioda T, de Silva T, Townend J, Jaye A, Whittle H, Rowland-Jones S, Cotten M. HIV-2 capsids distinguish high and low virus load patients in a West African community cohort. Vaccine. 2010 May 26;28 Suppl 2:B60-7.

Wichukchinda N, Nakajima T, Saipradit N, Nakayama EE, Ohtani H, Rojanawiwat A, Pathipvanich P, Ariyoshi K, Sawanpanyalert P, Shioda T, Kimura A. TIM1 haplotype may control the disease progression to AIDS in a HIV-1-infected female cohort in Thailand. AIDS. 2010 Jul 17;24(11):1625-31.

Maegawa H, Miyamoto T, Sakuragi J, Shioda T, Nakayama EE. Contribution of RING domain to retrovirus restriction by TRIM5alpha depends on combination of host and virus. Virology. 2010 Apr 10;399(2):212-20. Epub 2010 Jan 29.

Nakayama EE, Shioda T. Anti-retroviral activity of TRIM5 alpha. Rev Med Virol. 2010 Mar;20(2):77-92. Review.

2005-2009
Nakajima T, Nakayama EE, Kaur G, Terunuma H, Mimaya JI, Ohtani H, Mehra N, Shioda T, Kimura A. Impact of novel TRIM5alpha variants, Gly110Arg and G176del, on the anti-HIV-1 activity and the susceptibility to HIV-1 infection. AIDS. 2009 Oct 23;23(16):2091-100.

Kuroishi A, Saito A, Shingai Y, Shioda T, Nomaguchi M, Adachi A, Akari H, Nakayama EE. Modification of a loop sequence between alpha-helices 6 and 7 of virus capsid (CA) protein in a human immunodeficiency virus type 1 (HIV-1) derivative that has simian immunodeficiency virus (SIVmac239) vif and CA alpha-helices 4 and 5 loop improves replication in cynomolgus monkey cells. Retrovirology. 2009 Aug 3;6:70.

Kono K, Bozek K, Domingues FS, Shioda T, Nakayama EE. Impact of a single amino
acid in the variable region 2 of the Old World monkey TRIM5alpha SPRY (B30.2)
domain on anti-human immunodeficiency virus type 2 activity. Virology. 2009 May
25;388(1):160-8. Epub 2009 Apr 1. PubMed PMID: 19342071.

Maegawa H, Nakayama EE, Kuroishi A, Shioda T. Silencing of tripartite motif
protein (TRIM) 5alpha mediated anti-HIV-1 activity by truncated mutant of
TRIM5alpha. J Virol Methods. 2008 Aug;151(2):249-56. Epub 2008 Jun 3. PubMed
PMID: 18524394.

Sakuragi J, Sakuragi S, Ohishi M, Shioda T. A rapid recombination assay of
HIV-1 using murine CD52 as a novel biomarker. Microbes Infect. 2008
Apr;10(4):396-404. Epub 2008 Jan 9. PubMed PMID: 18407776.

Nakayama EE, Shingai Y, Kono K, Shioda T. TRIM5alpha-independent anti-human
immunodeficiency virus type 1 activity mediated by cyclophilin A in Old World
monkey cells. Virology. 2008 Jun 5;375(2):514-20. Epub 2008 Mar 25. PubMed PMID:
18367226.

Hosoya N, Miura T, Kawana-Tachikawa A, Koibuchi T, Shioda T, Odawara T,
Nakamura T, Kitamura Y, Kano M, Kato A, Hasegawa M, Nagai Y, Iwamoto A.
Comparison between Sendai virus and adenovirus vectors to transduce HIV-1 genes
into human dendritic cells. J Med Virol. 2008 Mar;80(3):373-82. PubMed PMID:
18205221.

Kono K, Song H, Shingai Y, Shioda T, Nakayama EE. Comparison of anti-viral
activity of rhesus monkey and cynomolgus monkey TRIM5alphas against human
immunodeficiency virus type 2 infection. Virology. 2008 Apr 10;373(2):447-56.
Epub 2008 Feb 21. PubMed PMID: 18201746.

Wichukchinda N, Nakayama EE, Rojanawiwat A, Pathipvanich P, Auwanit W,
Vongsheree S, Ariyoshi K, Sawanpanyalert P, Shioda T. Effects of CCR2 and CCRS
polymorphisms on HIV-1 infection in Thai females. J Acquir Immune Defic Syndr.
2008 Mar 1;47(3):293-7. PubMed PMID: 18197127.

Louisirirotchanakul S, Sutthent R, Wasi C, Chuenchitra T, Nitayaphan S, Brown
AE, Polonis VR, Nakayama EE, Shioda T, Liu H, Takebe Y. Host genetic analysis of
HIV type 1 subtype CRF01_AE (E)-infected Thai patients with different rates of
disease progression. AIDS Res Hum Retroviruses. 2007 Dec;23(12):1605-8. PubMed
PMID: 18160021.

Liu H, Nakayama EE, Theodorou I, Nagai Y, Likanonsakul S, Wasi C, Debre P,
Iwamoto A, Shioda T. Polymorphisms in CCR5 chemokine receptor gene in Japan. Int
J Immunogenet. 2007 Oct;34(5):325-35. PubMed PMID: 17845302.

Koh Y, Matsumi S, Das D, Amano M, Davis DA, Li J, Leschenko S, Baldridge A,
Shioda T, Yarchoan R, Ghosh AK, Mitsuya H. Potent inhibition of HIV-1 replication
by novel non-peptidyl small molecule inhibitors of protease dimerization. J Biol
Chem. 2007 Sep 28;282(39):28709-20. Epub 2007 Jul 17. PubMed PMID: 17635930.

Koizumi Y, Kageyama S, Fujiyama Y, Miyashita M, Lwembe R, Ogino K, Shioda T,
Ichimura H. RANTES -28G delays and DC-SIGN - 139C enhances AIDS progression in
HIV type 1-infected Japanese hemophiliacs. AIDS Res Hum Retroviruses. 2007
May;23(5):713-9. PubMed PMID: 17530998.

Wichukchinda N, Kitamura Y, Rojanawiwat A, Nakayama EE, Song H, Pathipvanich
P, Auwanit W, Sawanpanyalert P, Iwamoto A, Shioda T, Ariyoshi K. The
polymorphisms in DC-SIGNR affect susceptibility to HIV type 1 infection. AIDS Res
Hum Retroviruses. 2007 May;23(5):686-92. PubMed PMID: 17530994.

Lwembe R, Ochieng W, Panikulam A, Mongoina CO, Palakudy T, Koizumi Y,
Kageyama S, Yamamoto N, Shioda T, Musoke R, Owens M, Songok EM, Okoth FA,
Ichimura H. Anti-retroviral drug resistance-associated mutations among
non-subtype B HIV-1-infected Kenyan children with treatment failure. J Med Virol.
2007 Jul;79(7):865-72. PubMed PMID: 17516531.

Sakuragi J, Sakuragi S, Shioda T. Minimal region sufficient for genome
dimerization in the human immunodeficiency virus type 1 virion and its potential
roles in the early stages of viral replication. J Virol. 2007 Aug;81(15):7985-92.
Epub 2007 May 16. PubMed PMID: 17507464; PubMed Central PMCID: PMC1951301.

Song H, Nakayama EE, Yokoyama M, Sato H, Levy JA, Shioda T. A single amino
acid of the human immunodeficiency virus type 2 capsid affects its replication in
the presence of cynomolgus monkey and human TRIM5alphas. J Virol. 2007
Jul;81(13):7280-5. Epub 2007 May 2. PubMed PMID: 17475650; PubMed Central PMCID:
PMC1933286.

Nakayama EE, Carpentier W, Costagliola D, Shioda T, Iwamoto A, Debre P,
Yoshimura K, Autran B, Matsushita S, Theodorou I. Wild type and H43Y variant of
human TRIM5alpha show similar anti-human immunodeficiency virus type 1 activity
both in vivo and in vitro. Immunogenetics. 2007 Jun;59(6):511-5. Epub 2007 Apr 4.
PubMed PMID: 17406861.

Song H, Nakayama EE, Likanonsakul S, Wasi C, Iwamoto A, Shioda T. A
three-base-deletion polymorphism in the upstream non-coding region of human
interleukin 7 (IL-7) gene could enhance levels of IL-7 expression. Int J
Immunogenet. 2007 Apr;34(2):107-13. PubMed PMID: 17373935.

Ohishi M, Shioda T, Sakuragi J. Retro-transduction by virus pseudotyped with
glycoprotein of vesicular stomatitis virus. Virology. 2007 May 25;362(1):131-8.
Epub 2007 Jan 26. PubMed PMID: 17258261.

Shioda T, Nakayama EE. Human genetic polymorphisms affecting HIV-1 diseases.
Int J Hematol. 2006 Jul;84(1):12-7. Review. PubMed PMID: 16867896.

Sakuragi S, Sakuragi J, Morikawa Y, Shioda T. Development of a rapid and
convenient method for the quantification of HIV-1 budding. Microbes Infect. 2006
Jun;8(7):1875-81. Epub 2006 May 19. PubMed PMID: 16807037.

Nakayama EE, Maegawa H, Shioda T. A dominant-negative effect of cynomolgus
monkey tripartite motif protein TRIM5alpha on anti-simian immunodeficiency virus
SIVmac activity of an African green monkey orthologue. Virology. 2006 Jun
20;350(1):158-63. Epub 2006 May 2. PubMed PMID: 16647098.

Song H, Nakayama EE, Shioda T. Effects of human interleukin 7 on HIV-1
replication in monocyte-derived human macrophages. AIDS. 2006 Apr 4;20(6):937-9.
PubMed PMID: 16549982.

Wichukchinda N, Nakayama EE, Rojanawiwat A, Pathipvanich P, Auwanit W,
Vongsheree S, Ariyoshi K, Sawanpanyalert P, Shioda T. Protective effects of
IL4-589T and RANTES-28G on HIV-1 disease progression in infected Thai females.
AIDS. 2006 Jan 9;20(2):189-96. PubMed PMID: 16511411.

Mori K, Sugimoto C, Ohgimoto S, Nakayama EE, Shioda T, Kusagawa S, Takebe Y,
Kano M, Matano T, Yuasa T, Kitaguchi D, Miyazawa M, Takahashi Y, Yasunami M,
Kimura A, Yamamoto N, Suzuki Y, Nagai Y. Influence of glycosylation on the
efficacy of an Env-based vaccine against simian immunodeficiency virus SIVmac239
in a macaque AIDS model. J Virol. 2005 Aug;79(16):10386-96. PubMed PMID:
16051831; PubMed Central PMCID: PMC1182680.

Nakayama EE, Miyoshi H, Nagai Y, Shioda T. A specific region of 37 amino acid
residues in the SPRY (B30.2) domain of African green monkey TRIM5alpha determines
species-specific restriction of simian immunodeficiency virus SIVmac infection. J
Virol. 2005 Jul;79(14):8870-7. PubMed PMID: 15994780; PubMed Central PMCID:
PMC1168783.

2000-2004
Nakayama EE, Tanaka Y, Nagai Y, Iwamoto A, Shioda T. A CCR2-V64I polymorphism
affects stability of CCR2A isoform. AIDS. 2004 Mar 26;18(5):729-38. PubMed PMID:
15075507.

Sakuragi J, Ueda S, Iwamoto A, Shioda T. Possible role of dimerization in
human immunodeficiency virus type 1 genome RNA packaging. J Virol. 2003
Apr;77(7):4060-9. PubMed PMID: 12634365; PubMed Central PMCID: PMC150623.

Kawana-Tachikawa A, Tomizawa M, Nunoya J, Shioda T, Kato A, Nakayama EE,
Nakamura T, Nagai Y, Iwamoto A. An efficient and versatile mammalian viral vector
system for major histocompatibility complex class I/peptide complexes. J Virol.
2002 Dec;76(23):11982-8. PubMed PMID: 12414940; PubMed Central PMCID: PMC136879.

Murakami N, Ye Y, Kawanishi M, Aoki S, Kudo N, Yoshida M, Nakayama EE, Shioda
T, Kobayashi M. New Rev-transport inhibitor with anti-HIV activity from
Valerianae Radix. Bioorg Med Chem Lett. 2002 Oct 21;12(20):2807-10. PubMed PMID:
12270151.

Kano M, Matano T, Kato A, Shioda T, Nagai Y. Induction of HIV-1-specific
neutralizing antibodies in mice vaccinated with a recombinant Sendai virus
vector. Jpn J Infect Dis. 2002 Apr;55(2):59-60. PubMed PMID: 12082313.

Nakayama EE, Meyer L, Iwamoto A, Persoz A, Nagai Y, Rouzioux C, Delfraissy
JF, Debre P, McIlroy D, Theodorou I, Shioda T; SEROCO Study Group. Protective
effect of interleukin-4 -589T polymorphism on human immunodeficiency virus type 1
disease progression: relationship with virus load. J Infect Dis. 2002 Apr
15;185(8):1183-6. Epub 2002 Mar 20. PubMed PMID: 11930331.

Louisirirotchanakul S, Liu H, Roongpisuthipong A, Nakayama EE, Takebe Y,
Shioda T, Wasi C. Genetic analysis of HIV-1 discordant couples in Thailand:
association of CCR2 64I homozygosity with HIV-1-negative status. J Acquir Immune
Defic Syndr. 2002 Mar 1;29(3):314-5. PubMed PMID: 11873083.

Hoshino Y, Nakata K, Hoshino S, Honda Y, Tse DB, Shioda T, Rom WN, Weiden M.
Maximal HIV-1 replication in alveolar macrophages during tuberculosis requires
both lymphocyte contact and cytokines. J Exp Med. 2002 Feb 18;195(4):495-505.
PubMed PMID: 11854362; PubMed Central PMCID: PMC2193627.

Sakuragi J, Iwamoto A, Shioda T. Dissociation of genome dimerization from
packaging functions and virion maturation of human immunodeficiency virus type 1.
J Virol. 2002 Feb;76(3):959-67. PubMed PMID: 11773371; PubMed Central PMCID:
PMC135806.

Xin X, Nakamura K, Liu H, Nakayama EE, Goto M, Nagai Y, Kitamura Y, Shioda T,
Iwamoto A. Novel polymorphisms in human macrophage inflammatory protein-1 alpha
(MIP-1alpha) gene. Genes Immun. 2001 May;2(3):156-8. PubMed PMID: 11426325.

Mori K, Yasutomi Y, Ohgimoto S, Nakasone T, Takamura S, Shioda T, Nagai Y.
Quintuple deglycosylation mutant of simian immunodeficiency virus SIVmac239 in
rhesus macaques: robust primary replication, tightly contained chronic infection,
and elicitation of potent immunity against the parental wild-type strain. J
Virol. 2001 May;75(9):4023-8. PubMed PMID: 11287551; PubMed Central PMCID:
PMC114147.

Shioda T, Nakayama EE, Tanaka Y, Xin X, Liu H, Kawana-Tachikawa A, Kato A,
Sakai Y, Nagai Y, Iwamoto A. Naturally occurring deletional mutation in the
C-terminal cytoplasmic tail of CCR5 affects surface trafficking of CCR5. J Virol.
2001 Apr;75(7):3462-8. PubMed PMID: 11238872; PubMed Central PMCID: PMC114139.

Sakuragi J, Shioda T, Panganiban AT. Duplication of the primary encapsidation
and dimer linkage region of human immunodeficiency virus type 1 RNA results in
the appearance of monomeric RNA in virions. J Virol. 2001 Mar;75(6):2557-65.
PubMed PMID: 11222678; PubMed Central PMCID: PMC115878.

Nakayama EE, Wasi C, Ajisawa A, Iwamoto A, Shioda T. A new polymorphism in
the promoter region of the human interleukin-16 (IL-16) gene. Genes Immun.
2000;1(4):293-4. PubMed PMID: 11196708.

Watanabe T, Nakamura K, Wakugawa M, Kato A, Nagai Y, Shioda T, Iwamoto A,
Tamaki K. Antibodies to molluscum contagiosum virus in the general population and
susceptible patients. Arch Dermatol. 2000 Dec;136(12):1518-22. PubMed PMID:
11115164.

Ohnishi Y, Senda T, Nandhagopal N, Sugimoto K, Shioda T, Nagal Y, Mitsui Y.
Crystal structure of recombinant native SDF-1alpha with additional mutagenesis
studies: an attempt at a more comprehensive interpretation of accumulated
structure-activity relationship data. J Interferon Cytokine Res. 2000
Aug;20(8):691-700. PubMed PMID: 10954912.

Nakayama EE, Hoshino Y, Xin X, Liu H, Goto M, Watanabe N, Taguchi H, Hitani
A, Kawana-Tachikawa A, Fukushima M, Yamada K, Sugiura W, Oka SI, Ajisawa A, Sato
H, Takebe Y, Nakamura T, Nagai Y, Iwamoto A, Shioda T. Polymorphism in the
interleukin-4 promoter affects acquisition of human immunodeficiency virus type 1
syncytium-inducing phenotype. J Virol. 2000 Jun;74(12):5452-9. PubMed PMID:
10823849; PubMed Central PMCID: PMC112029.