／Research Center for Mechanism and Regulation of Aging About Research Center

The life expectancy of humans has increased markedly over recent decades. Ironically, this has resulted in a startling rise in the incidence of aging-associated diseases, resulting in serious social problems such as increased medical expenses and nursing care costs. To solve these problems, the Research Center for Mechanism and Regulation of Aging was established in2017. The center aims to clarify the fundamental mechanisms that regulate aging and to understand the role of cellular senescence in aging and aging-associated diseases.

Director, Prof. : Eiji Hara (concur.)

Division of Aging Model Organism

Department of Aging Rate Biology	Head: Invited Professor Eisuke Nishida （RIKEN Center for Biosystems Dynamics Research, Director）
Department of Research of Signals Regulating Aging	Head: Invited Professor Naoki Hisamoto （Group of Signaling Mechanisms, Graduate School of Science, Nagoya University.）
Department of Genetics and Metabolism	Head: Invited Professor Masayuki Miura （Dept. of Genetics, Graduate School of Pharmaceutical Sciences, University of Tokyo）
Department of Cell-cell Communication	Head: Invited Professor Tatsushi Igaki （Lab of Genetics, Graduate School of Biostudies, Kyoto University）
Department of Organismal Aging Research	Head: Invited Professor Tohru Ishitani （Lab of Integrated Signaling Systems, Institute for Molecular & Cellular Regulation , Gunma University）
Department of Autophagy and Aging	Head: Concurrent Professor Tamotsu Yoshimori （Lab of Intracellular Membrane Dynamics, Graduate School of Frontier Biosciences, Osaka University.）
Department of Sleep and Aging Regulation	Head: Invited Researcher Akiko Sato （National Center for Geriatrics and Gerontology）
Department of Reproductive Aging	Head: Concurrent Professor Masahito Ikawa （Dept. of Experimental Research, Research Institute for Microbial Diseases, Osaka University）
Department of Animal Longevity and Aging Research	Head: Invited Associate Professor Kyoko Miura （Biomedical Animal Research Laboratory, Intsitute for Genetic Medicine, Hokkaido University）

Division of Cellular Senescence

Department of Cell Senescence Mechanism	Head: Concurrent Professor Eiji Hara （Dept. of Molecular Microbiology, Research Institute for Microbial Diseases, Osaka University）
Department of Aging-associated Stress Signaling	Head: Invited Professor Hidenori Ichijo （Lab of Cell Signaling, Graduate School of Pharmaceutical Sciences, The University of Tokyo）
Department of Senescent Cell Morphology & Motility	Head: Invited Professor: Yasuhiro Minami （Dept. of Physiology and Cell Biology, Graduate School of Medicine, Kobe University）
Department of Senescence Regulation	Head: Invited Professor Nakanishi Makoto （Div. of Cancer Cell Biology, The Insitute of Medical Science, The University of Tokyo）
Department of Transposon-Mediated Processes	Head: Invited Professor Haruhiko Shiomi （Dept. of Molecular Biology, Keio University School of Medicine）
Department of Senescent Metabolism	Head: Invited Researcher Tomonori Kimura （KAGAMI Project, National Institutes of Biomedical Innovation, Health and Nutrition）
Department of Immune Aging	Head: Invited Professor Yoko Hamazaki （Dept. of Life Science Frontiers, Center for iPS Cell Research and Application, Kyoto University）
Department of Brain Aging	Head: Invited Researcher Kiyohito Mizutani （Div. of Pathogenic Signaling, Graduate School of Medicine, Kobe University）

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