1985年以前のもの

Mice Deficient in the Axonemal Protein Tektin-t Exhibit Male Infertility and Immotile-Cilium Syndrome Due to Impaired Inner Arm Dynein Function.
Tanaka H, Iguchi N, Toyama Y, Kitamura K, Takahashi T, Kaseda K, Maekawa M, Nishimune Y.
Mol Cell Biol. 2004 Sep;24(18):7958-64.

Characterization of a Novel Postacrosomal Perinuclear Theca-Specific Protein, CYPT1.
Kitamura K, Iguchi N, Kaneko Y, Tanaka H, Nishimune Y.
Biol Reprod. 2004 Jul 30 [Epub ahead of print]

Ketone bodies could support the motility but not the acrosome reaction of mouse sperm.
Tanaka H, Takahashi T, Iguchi N, Kitamura K, Miyagawa Y, Tsujimura A, Matsumiya K, Okuyama A, Nishimune Y.
Int J Androl. 2004 Jun;27(3):172-7.

Cloning and characterization of a mouse spergen-1 localized in sperm mitochondria.
Matsuoka Y, Iguchi N, Kitamura K, Nishimura H, Manabe H, Miyagawa Y, Koga M, Matsumiya K, Okuyama A, Tanaka H, Nishimune Y.
Int J Androl. 2004 Jun;27(3):152-60.

In vivo and in vitro constant expression of GATA-4 in mouse postnatal Sertoli cells.
Imai T, Kawai Y, Tadokoro Y, Yamamoto M, Nishimune Y, Yomogida K.
Mol Cell Endocrinol. 2004 Feb 12;214(1-2):107-15.

Gene structure and evolution of testicular haploid germ cell-specific genes, Oxct2a and Oxct2b.
Onishi M, Yasunaga T, Tanaka H, Nishimune Y, Nozaki M.
Genomics. 2004 Apr;83(4):647-57.

Transient expression analysis of the mouse ornithine decarboxylase antizyme haploid-specific promoter using in vivo electroporation.
Ike A, Ohta H, Onishi M, Iguchi N, Nishimune Y, Nozaki M.
FEBS Lett. 2004 Feb 13;559(1-3):159-64.

p53 Protein interacts specifically with the meiosis-specific mammalian RecA-like protein DMC1 in meiosis.
Habu T, Wakabayashi N, Yoshida K, Yomogida K, Nishimune Y, Morita T.
Carcinogenesis. 2004 Jun;25(6):889-93. Epub 2004 Feb 04.

Rosbin: a novel homeobox-like protein gene expressed exclusively in round spermatids.
Takahashi T, Tanaka H, Iguchi N, Kitamura K, Chen Y, Maekawa M, Nishimura H, Ohta H, Miyagawa Y, Matsumiya K, Okuyama A, Nishimune Y.
Biol Reprod. 2004 May;70(5):1485-92. Epub 2004 Jan 14.

Control of mouse hils1 gene expression during spermatogenesis: identification of regulatory element by transgenic mouse.
Iguchi N, Tanaka H, Yamada S, Nishimura H, Nishimune Y.
Biol Reprod. 2004 May;70(5):1239-45. Epub 2003 Dec 26.

Commitment of fetal male germ cells to spermatogonial stem cells during mouse embryonic development.
Ohta H, Wakayama T, Nishimune Y.
Biol Reprod. 2004 May;70(5):1286-91. Epub 2003 Dec 26.

　2003年

Isolation and characterization of a novel cDNA encoding a DNA-binding protein (Hils1) specifically expressed in testicular haploid germ cells.
Iguchi N, Tanaka H, Yomogida K, Nishimune Y.
Int J Androl. 2003 Dec;26(6):354-65.

In vitro and in vivo gene delivery by recombinant baculoviruses.
Tani H, Limn CK, Yap CC, Onishi M, Nozaki M, Nishimune Y, Okahashi N, Kitagawa Y, Watanabe R, Mochizuki R, Moriishi K, Matsuura Y.
J Virol. 2003 Sep;77(18):9799-808.

Haprin, a novel haploid germ-cell-specific RING finger protein involved in the acrosome reaction.
Kitamura K, Tanaka H, Nishimune Y.
J Biol Chem. 2003 Nov 7;278(45):44417-23

Methylation of CpG dinucleotides in the open reading frame of a testicular germ cell-specific intronless gene, Tact1/Actl7b, represses its expression in somatic cells.
Hisano M, Ohta H, Nishimune Y, Nozaki M.
Nucleic Acids Res. 2003 Aug 15;31(16):4797-804.

Proliferation and Differentiation of Spermatogonial Stem Cells in the W/Wv Mutant Mouse Testis.
Ohta H, Tohda A, Nishimune Y.
Biol Reprod. 2003 Jul 30 [Epub ahead of print]

Dramatic expansion of germinal stem cells by ectopically expressed human glial cell line-derived neurotrophic factor in mouse sertoli cells.
Yomogida K, Yagura Y, Tadokoro Y, Nishimune Y.
Biol Reprod. 2003 Oct;69(4):1303-7. Epub 2003 Jun 11.

Characterization of Histone H2A.X Expression in Testis and Specific Labeling of Germ Cells at the Commitment Stage of Meiosis with Histone H2A.X Promoter-Enhanced Green Fluorescent Protein Transgene.
Tadokoro Y, Yomogida K, Yagura Y, Yamada S, Okabe M, Nishimune Y.
Biol Reprod. 2003 Oct;69(4):1325-9. Epub 2003 Jun 11.

Involvement of death receptor Fas in germ cell degeneration in gonads of Kit-deficient W(v)/W(v) mutant mice.
Sakata S, Sakamaki K, Watanabe K, Nakamura N, Toyokuni S, Nishimune Y, Mori C, Yonehara S.
Cell Death Differ 2003 Jun;10(6):676-86

Molecular cloning and characterization of the human orthologue of the oppo 1 gene encoding a sperm tail protein.
Kitamura K, Miyagawa Y, Iguchi N, Nishimura H, Tanaka H, Nishimune Y.
Mol Hum Reprod 2003 May;9(5):237-43

Genomic structure and promoter activity of the testis haploid germ cell-specific intronless genes, Tact1 and Tact2.
Hisano M, Yamada S, Tanaka H, Nishimune Y, Nozaki M.
Mol Reprod Dev 2003 Jun;65(2):148-56

Novel Actin-Like Proteins T-ACTIN 1 and T-ACTIN 2 Are Differentially Expressed in the Cytoplasm and Nucleus of Mouse Haploid Germ Cells.
Tanaka H, Iguchi N, De Carvalho CE, Tadokoro Y, Yomogida K, Nishimune Y.
Biol Reprod. 2003 Aug;69(2):475-82. Epub 2003 Apr 02.

The role of the c-kit receptor in the regenerative differentiation of rat Leydig cells.
Tsuchida J, Dohmae K, Kitamura Y, Nishimune Y.
Int J Androl 2003 Apr;26(2):121-5

A novel protein phosphatase 2C family member (PP2Czeta) is able to associate with ubiquitin conjugating enzyme 9.
Kashiwaba M, Katsura K, Ohnishi M, Sasaki M, Tanaka H, Nishimune Y, Kobayashi T, Tamura S.
FEBS Lett 2003 Mar 13;538(1-3):197-202

Functional Analysis of the p53 Gene in Apoptosis Induced by Heat Stress or Loss of Stem Cell Factor Signaling in Mouse Male Germ Cells.
Ohta H, Aizawa S, Nishimune Y.
Biol Reprod 2003 Jun;68(6):2249-54

Single nucleotide polymorphisms in the protamine-1 and -2 genes of fertile and infertile human male populations.
Tanaka H, Miyagawa Y, Tsujimura A, Matsumiya K, Okuyama A, Nishimune Y.
Mol Hum Reprod 2003 Feb;9(2):69-73

Differential expression of succinyl CoA transferase (SCOT) genes in somatic and germline cells of the mouse testis.
Tanaka H, Iguchi N, Miyagawa Y, Koga M, Kohroki J, Nishimune Y.
Int J Androl 2003 Feb;26(1):52-6

Structure and promoter activity of the gene encoding ornithine decarboxylase antizyme expressed exclusively in haploid germ cells in testis (OAZt/Oaz3).
A. Ike, S. Yamada, H. Tanaka, Y. Nishimune and M. Nozaki.
Gene, 298, 183-193 (2002).

Electroporated transgene-rescued spermatogenesis in infertile mutant mice with a sertoli cell defect.
K. Yomogida, Y. Yagura and Y. Nishimune.
Biol. Reprod., 67, 712-717 (2002).

Type XXVI collagen, a new member of the collagen family, is specifically expressed in the testis and ovary.
K. Sato, K. Yomogida, T. Wada, T. Yorihuzi, Y. Nishimune, N. Hosokawa and K. Nagata.
Biol. Chem., 277, 37678-37684 (2002).

Nectin couples cell-cell adhesion and the actin scaffold at heterotypic testicular junctions.
Ozaki-Kuroda K, Nakanishi H, Ohta H, Tanaka H, Kurihara H, Mueller S, Irie K, Ikeda W, Sakai T, Wimmer E, Nishimune Y, Takai Y.
Curr. Biol., 12,1145-1150 (2002).

Molecular cloning and characterization of oppo 1: a haploid germ cell-specific complementary DNA encoding sperm tail protein.
Nakamura Y, Tanaka H, Koga M, Miyagawa Y, Iguchi N, Egydio de Carvalho C, Yomogida K, Nozaki M, Nojima H, Matsumiya K, Okuyama A, Nishimune Y.
Biol. Reprod., 67, 1-7 (2002).

Spermatogonia-dependent expression of testicular genes in mice.
Tanaka K, Tamura H, Tanaka H, Katoh M, Futamata Y, Seki N, Nishimune Y, Hara T.
Dev. Biol., 246, 466-479 (2002).

Molecular cloning and characterization of the human orthologue of male germ cee-specific action capping protein alpha3(cpalpha3).
Y. Miyagawa, H. Tanaka, N. Iguchi, K. Kitamura, Y. Nakamura, T. Takahashi, K. Matsumiya, A. Okuyama and Y. Nishimune.
Mol. Hum. Reprod., 8, 531-539 (2002).

Cloning and characterization of the human tektin-t gene.
N. Iguchi, H. Tanaka, Y. Nakamura, M. Nozaki, T. Fujiwara and Y. Nishimune.
Mol. Hum. Reprod., 8, 525-530 (2002).

Development of the stages of the cycle in mouse seminiferous epithelium after transplantation of green fluorescent protein-labeled spermatogonial stem cells.
Ventela S, Ohta H, Parvinen M, Nishimune Y.
Biol. Reprod., 66, 1422-1429 (2002).

Use of stepwise subtraction to comprehensively isolate mouse genes whose transcription is up-regulated during spermiogenesis.
Fujii T, Tamura K, Masai K, Tanaka H, Nishimune Y, Nojima H.
EMBO Rep., 3, 367-372 (2002).

Homeostatic regulation of germinal stem cell proliferation by the GDNF/FSH pathway.
Y. Tadokoro, K. Yomogida, H. Ohta, A. Tohda and Y. Nishimune
Mech. Dev., 113, 29-39 (2002).

Molecular cloning and characterization of a complementary DNA encoding sperm tail protein SHIPPO 1.
Egydio de Carvalho C, Tanaka H, Iguchi N, Ventela S, Nojima H, Nishimune Y.
Biol. Reprod. 66:785-795 (2002).

Induction of instability of p34(cdc2) expression by treatment with cisplatin (CDDP) in mouse teratocarcinoma F9 cells.
Doi T, Morita T, Wakabayashi N, Sumi T, Iwai SA, Amekawa S, Sakuda M, Nishimune Y.
Cancer Lett., 176, 75-80 (2002)

Germ cells and genetic regulation of spermatogenesis.
H. Tanaka and Y. Nishimune.
Asian J. Androl., 3, 18-20 (2002).

Cloning and characterization of male germ-cell-specific genes.
H. Tanaka, M. Nozaki, K. Yomogida and Y. Nishimune.
Testicular Tangrams, Rommerts FFG and Teerds KJ, Springer, 55-73 (2002).

Restoration of spermatogenesis and fertility in azoospermic mutant mice by suppression and reelevation of testosterone followed by intracytoplasmic sperm injection.
Tohda A, Okuno T, Matsumiya K, Okabe M, Kishikawa H, Dohmae K, Okuyama A, Nishimune Y.
Biol. Reprod., 66, 85-90 (2002)

Cloning and characterization of a human orthologue of testis-specific succiny1 CoA: 3-oxo acid CoA transferase (Scot-t) cDNA
H. Tanaka, J. Kohroki, N. Iguchi, M. Onishi and Y. Nishimune
Mol. Hum. Reprod., 8, 16-23 (2002).

Identification and sequencing the juvenile spermatogonial depletion critical interval on mouse chromosome 1 reveals the presence of eight candidate genes.
H. Boettger-Tong, J. Rohozinski, A. Agoulnik, K. Dohmae, Y. Nishimune, N. Levy and C. Bishop
Biochem. Biophys. Res. Commun., 16, 1129-1135 (2001).

Calmegin is required for fertilin alpha/beta heterodimerization and sperm fertility.
M. Ikawa, T. Nakanishi, S. Yamada, I. wada, K. Kominami, H. Tanaka, M. Nozaki, Y. Nishimune and M. Okabe
Dev. Biol., 240, 254-261 (2001).

Transcription factor BACH1 is recruited to the nucleus by its novel alternative spliced isoform
R. Kanezaki, T. Toki, M. Yokoyama, k. Yomogida, K. Sugiyama, M. Yamamoto, K. Igarashi and E. Ito
J. Biol. Chem., 276, 7278-7284 (2001).

Two mouse piwi-related genes: miwi and mili
S. Kuramochi-miyagawa, T. Kimura, K. Yomogida, A. Kuroiwa, Y. Tadokoro, Y. Fujita, M. Sato, Y. Matsuda and T. Nakano
Mech. Dev., 108, 121-133 (2001).

Defect in germ cells, not in supporting cells, is the cause of male infertility in the jsd mutant mouse: proliferation of spermatogonial stem cells without differentiation
H. Ohta, K. Yomogida, Y. Tadokoro, A. Thoda, K. Dohmae and Y. Nishimune
Int. J. Androl., 24, 15-23 (2001).

The ter/ter gonadal somatic cells cause apoptosis in ter/ter primordial germ cells (PGCs) with normal survivability and proliferation ability in the mouse: evidence from PGC-Somatic cell "exchange-co-culture"
S. Takabayashi, M. Nozaki, K. Ishikawa and M. Noguchi
Zool. Sci., 18, 695-704 (2001).

Cloning and charcterization of human haspin gene encoding haploid germ cell-specific nuclear protein kinase
H. Tanaka, V. Iguchi, V. Nakamura, J. Kohroki, V. Carbalho and Y. Nishimune
Mol. Hum. Reprod., 7, 211-218 (2001).

Isolation and characterzation of haplioid germ cell-specific succinyl CoA: 3-oxo acid CoA transferase
H. Tanaka, M. Koga, N. Iguchi, M. Nozaki, M. Onishi, C. de Carvlho, Y. Nakamura, Y. Miyagawa, M. Takeyma, K. Matsumiya, A. Okuyama and Y. Nishimune
Andrology in the 21st Century. Proceeding of VIIth International Congress of Androloty, 157-161 (2001) .

Testosterone suppresses spermatogenesis in juvenile spermatogonial depletion(jsd) mice.
A. Tohda, K. Matsumiya, Y. Tadokoro, K. Yomogida, Y. Miyagawa, A. Okuyama and Y. Nishimune
Biol. Reprod., 65, 532-537 (2001).

Microbiological contamination in genetically modified animals and proposals for a microbiological test standard for national universities in Japan
H. Yamamoto, H. Sato, K. Yagami, J. Arikawa, M. Furuya, T. Kurosawa, K. Mannen, K. Matsubayashi, Y. Nishimune, T. Shibahara, T. Ueda and T. Itoh
Exp. Anim., 50, 397-407 (2001).

Nested genomic structure of haploid germ cell specific haspin gene.
Y. Yoshimura, H. Tanaka, M. Nozaki, K. Yomogida, T. Yasunaga and Y. Nishimune
Gene, 267, 49-54 (2001).

遺伝子から見た哺乳動物精子形成の特徴
野崎　正美
関西実験動物研究会会報, 22, 116-120 (2001).

Regulation of the differentiation of the undifferentiated spermatogonia
G. de Rooij, H. G. J. B. Schrans-Stassen, M. M. A. van Pelt, G. A. Shuttleslworth, L. M. Meistrich, M. Okabe and Y. Nishimune
The Testis From Stem Cell to Sperm Function, E. Goldberg, Springer. USA, 43-54 (2000) .

Isolation and characterization of a haploid germ cell-specific novel complementary deoxyribonucleic acid; testis-specific homologue of succinyl CoA:3-Oxo acid CoA transferase.
M. Koga, H. Tanaka, K. Yomogida, M. Nozaki, J. Tsuchida, H. Ohta, Y. Nakamura, K. Masai, Y. Yoshimura, M. Yamanaka, N. Iguchi, H. Nojima, K. Matsumiya, A. Okuyama and Y. Nishimune
Biol Reprod., 63, 1601-1609 (2000).

Identification of differentiation antigens in mouse testicular germ cells recognized by monoclonal antibody TRA 55.
X. Ling, H. Tanaka, J. Tsuchida and Y. Nishimune
Int J Androl., 23, 29-35. (2000).

Prostate-specific transcription factor hPSE is translated only in normal prostate epithelial cells
M. Nozawa, K. Yomogida, N. Kanno, N. Nonomura, T. Miki, A. Okuyama, Y. Nishimune and M. Nozaki
Canser Res., 60, 1348-1352 (2000).

Regulation of proliferation and differentiation in spermatogonial stem cells: the role of c-kit and its ligand SCF
H. Ohta, K. Yomogida, K. Dohmae and Y. Nishimune
Development, 127, 2125-2131 (2000).

Real-time observation of transplanted 'green germ cells': Proliferation and differentiation of stem cells
H. Ohta, K. Yomogida, S. Yamada, M. Okabe and Y. Nishimune
Dev. Growth Differ., 42, 105-112 (2000).

The effect of caffeine on p53-dependent radioresponses in undifferentiated mouse embryonal carcinoma cells after X-ray and UV-irradiations.
M. Taga, K. Shiraishi, T. Shimura, N. Uematsu, t. Kato, Y. Nishimune, S. Aizawa, M. Oshimura and O. Niwa
J. Radiat. Res., 41, 227-241 (2000).

Cytokeratins 8 and 19 in the mouse placental development
Y. Tamai, T.-O. Ishikawa, R. Bosl, M. Mori, M. Nozaki, H. Baribault, G. Ohima and M. Taketo
J. Cell Biol., 151, 563-572 (2000).

Identification and characterization of testis specific ornithine decarboxylase antizyme (OAZ-t) gene: expression in haploid germ cells and polyamine-induced frameshifting.
Y. Tosaka, H. Tanaka, Y. Yano, K. Masai, M. Nozaki, K. Yomogida, S. Otani, H. Nojima and Y. Nishimune
Genes Cells, 5, 265-276 (2000).

Cloning and characterization of a complementary deoxyribonucleic acid encoding haploid-specific alanine-rich acidic protein located on chromosome-X
K. Uchida, J. Tsuchida, H. Tanaka, M. Koga, Y. Nishina, M. Nozaki, K. Yoshinaga, k. Toshimori, K. Matsumiya, A. Okuyama and Y. Nishimune
Biol. Rprod., 63, 993-999 (2000).

Regulation of acrosome formation in mice expressing green fluorescent protein as a marker.
S. Ventela, M. Mulari, M. Okabe, H. Tanaka, Y. Nishimune, J. Toppari and M. Parvinen
Tissue Cell, 32, 501-507 (2000).

Expression of green fluorescent protein under beta-actin promoter in living spermatogenic cells of the mouse: stage-specific regulation by FSH.
S. Ventela, M. Okabe, H. Tanaka, Y. Nishimune, J. Toppari and M. Parvinen
Int. J. Androl., 23, 236-242 (2000).

A novel cis-Acting element regulates HES-1 gene expression in P19 embryonal carcinoma cells treated with retinoic acid.
N. Wakabayashi, R. Kageyama, T. Habu, T. Doi , T. Morita, M. Nozaki, M. Yamamoto and Y. Nishimune
J. Biochem., 128, 1087-1095 (2000).

Structure, expression, and chromosome mapping of LATS2, a mammalian homologue of the Drosophila tumor suppressor gene lats/warts.
N. Yabuta, T. Fujii , N. Copeland, D. Gilbert, N. Jenkins, H. Nishiguchi, Y. Endo, S. Toji, H. Tanaka, Y. Nishimune and H. Nojima
Genomics, 63, 263-270 (2000).

Cloning and expression of the mouse Pse gene encoding a novel Ets family member
N. Yamada, Y. Tamai, H. Miyamoto and M. Nozaki
Gene, 241, 267-274 (2000).

Molecular cloning and characterization of phosphatidylcholine transfer protein-like protein gene expressed in murine haploid germ cells.
M. Yamanaka, M. Koga, H. Tanaka, Y. Nakamura, H. Ohta, K. Yomogida, J. Tsuchida, N. Iguchi, H. Nojima, M. Nozaki, K. Matsumiya, A. Okuyama, K. Toshimori and Y. Nishimune
Biol Reprod, 62, 1694-1701 (2000).

哺乳類精子形成の分子生物学
野崎　正美
J. Reprod. Dev., 46, 39-42 (2000).

精子形成に対する分子生物学的アプローチ
野崎　正美, 田中　宏光 and 西宗　義武
Pharma Medica, 18, 13-18 (2000).

マウスにおける精子形成の機構
西宗　義武
哺乳動物の生殖細胞と細胞工学, 120-126 (2000).
　

Arrest of spermatogonial differentiation in jsd/jsd, Sl17H/Sl17H, and cryptorchid mice
G. de Rooij, M. Okabe and Y. Nishimune
Biol. Reprod., 61, 842-847 (1999).

Sperizin is a murine RING zinc-finger protein specifically expressed in haploid germ cells
T. Fujii, K. Tamura, N. Copeland, D. Gilbert, N. Jenkins, k. Yomogida, H. Tanaka, Y. Nishimune and H. Nojima
Genomics, 57, 94-101 (1999).

Molecular cloning of haploid germ cell-specific tektin cDNA and analysis of the protein in mouse testis
N. Iguchi, H. Tanaka, T. Fujii, K. Tamura, H. Nojima and Y. Nishimune
FEBS Lett., 456, 315-321 (1999).

Molecular cloning and genomic organization of mouse homologue of Drosophila germ cell-less and its expression in germ lineage cells
T. Kimura, K. Yomogida, N. Iwai, Y. Kato and T. Nakano
Biochem. Biophys. Res. Commun., 262, 223-230 (1999).

Hepatoma-derived growth factor-related protein(HRP)-1 gene in spermatogenesis in mice
T. Kuroda, H. Tanaka, H. Nakamura, Y. Nishimune and T. Kishimoto
Biochem. Biophys. Res. Commun., 262, 433-437 (1999).

Stimulation of spermatogonial differentiation in juvenile spermatogonial depletion (jsd) mutant mice by gonadotropin-releasing hormone antagonist treatment.
K. Matsumiya, M. Meistrich, G. Shetty, K. Dohmae, A. Thoda, A. Okuyama and Y. Nishimune
Endocrinology, 140, 4912-4915 (1999).

Real-time observation of acrosomal dispersal from mouse sperm using GFP as a marker protein
T. Nakanishi, M. Ikawa, S. Yamada, M. Parvinen, T. Baba, Y. Nishimune and M. Okabe
FEBS Lett., 449, 277-283 (1999).

Developmental abnormalities of glycosylphosphatidylinositol-anchor-deficient embryos revealed by Cre/loxP system
M. Nozaki, K. Ohishi, N. Yamada, T. Kinoshita, A. Nagy and J. Takeda
Lab. Inv., 79, 293-299 (1999).

The putative chaperone calmegin and sperm fertility
M. Okabe, M. Ikawa, S. Yamada, T. Nakanishi, T. Baba and Y. Nishimune
The Male Gamete: from basic science to clinical applicarion,
C. G. M. University, 48-54 (1999) .

Identification and characterization of a haploid germ cell-specific nuclear protein kinase (Haspin) in spermatid nuclei and its effects on somatic cells
H. Tanaka, Y. Yoshimura, M. Nozaki, K. Yomogida, H. Nojima and Y. Nishimune
J. Biol. Chem., 274, 17049-17057 (1999).

Progressive impairment of kidneys and reproductive organs in mice lacking Rho GDlalpha
A. Togawa, J. Miyoshi, H. Ishizaki, M. Tanaka, A. Takakura, H. Nishioka, H. Yoshida, T. Doi, A. Mizoguchi, N. Matsuura, Y. Niho, Y. Nishimune, S. Nishikawa and Y. Takai
Oncogene, 18, 5373-5380 (1999).

Genomic analysis of male germ cell-specific actin capping protein alpha.
Y. Yoshimura, H. Tanaka, M. Nozaki, K. Yomogida, K. Shimamura, T. Yasunaga and Y. Nishimune
Gene, 237, 193-199 (1999).
　

Maternal transfer of Hantavirus antibodies in rats
K. Dohmae and Y. Nishimune
Lab. Anim. Sci., 48, 395-397 (1998).

Generating green fluorescent mice by germline transmission of green fluorescent ES cells
A. Hadjantonakis, M. Gertsenstein, M. Ikawa, M. Okabe and A. Nagy
Mech. Dev., 76, 79-90 (1998).

Non-invasive sexing of preimplantation stage mammalian embryos
A. Hadjantonakis, M. Gertsenstein, M. Okabe and A. Nagy
Nat. Genet., 19, 220-222 (1998).

Effects of epidermal growth factor on the invasion activity of the bladder cancer cell line
N. Kanno, N. Nonomura, T. Miki, Y. Kojima, S. Takahara, M. Nozaki and A. Okuyama
J. Urol., 159, 586-590 (1998).

Expression of selenoprotein-P messenger ribonucleic acid in the rat testis
M. Koga, H. Tanaka, K. Yomogida, J. Tsuchida, K. Uchida, M. Kitamura, S. Sakoda, K. Matsumiya, A. Okuyama and Y. Nishimune
Biol. Reprod., 58, 261-265 (1998).

Physical and genetic linkage of glutaminase (Gls), signal transducer and activator of transcription 1 (Stat1), and xeroderma pigmentosum complementation gruop G (Xpg) on mouse proximal chromosome 1
N. Levy, H. Boettger-Tong, K. Dohmae, A. Agoulnik, T. Ty, Y. Nishimune and C. Bishop
Genomics, 54, 355-356 (1998).

Human Papillomavirus-induced carcinogenesis with p53 deficiency in mouse: novel lymphomagenesis in HPV16E6E7 transgenic mice mimicking p53 defect
Q. Li, N. Yoshioka, M. Yutsudo, S. Inafuku, K. Aozasa, Y. Kitamura, S. Aizawa, Y. Nishimune, A. Hakura and G. Kondoh
Virologoy, 252, 28-33 (1998).

Stage-specific localization of Basigin, a member of the immunoglobulin superfamily, during mouse spermatogenesis
M. Maekawa, F. Suzuki-Toyota, Y. Toyama, K. Kadomatsu, N. Hagihara, N. Kuno, K. Muramatsu, K. Dohmae and S. Yuasa
Arch. Histol. Cytol., 61, 405-415 (1998).

Defective stratum corneum and early neonatal death in mice lacking the gene for transglutaminase 1 (keratinocyte transglutaminase)
M. Matsuki, F. Yamashita, A. Yamamoto, K. Yamada, C. Kinoshita, S. Fushiki, E. Ueda, Y. Morishima, K. Tabata, H. Yasuno, M. Hashida, H. Iizuka, M. Ikawa, M. Okabe, G. Kondoh, T. Kinoshita, J. Takeda and K. Yamanishi
Proc. Natl. Acad. Sci. U S A, 95, 1044-1049 (1998).

Prevention of hyperacute rejection by phosphatidylinositol-anchored mini-complement receptor type1
S. Mikata, S. Miyagawa, M. Yoshitatsu, M. Ikawa, M. Okabe, H. Matsuda and R. Shirakura
Transpl. Immunol., 6, 107-110 (1998).

Male infertility and the genetics of spermatogenesis
M. Okabe, M. Ikawa and J. Ashkenas
Am. J. Hum. Genet., 62, 6-13 (1998).

Characterization and expression of a stage specific antigen by monoclonal antibody TRA 54 in testicular germ cells.
L. A. V. D. Pereira, H. Tanaka, Y. Nagata, K. Sawada, H. Mori, L. M. C. Chimelli and Y. Nishimune
Int. J. Androl., 21, 34-40 (1998).

Prevalence of herpes B virus antibody in nonhuman primates reared at the national university of Japan.
H. Sato, J. Arikawa, M. Furuya, J. Kitoh, K. Mannen, Y. Nishimune, K. Ohsawa, T. Serikawa, T. Shibahara, Y. Watanabe, K. Yagami, H. Yamamoto and Y. Yoshikawa
Exp. Anim., 47, 199-202 (1998).

Functional competence of T cells in the absence of glycosylphosphatidylinositol-anchored proteins caused by T cell-specific disruption of th Pig-a gene
Y. Takahama, K. Ohishi, Y. Tokoro, T. Sugawara, Y. Yoshimura, M. Okabe, T. Kinoshita and J. Takeda
Eur. J. Immunol, 28, 2159-2166 (1998).

Cloning and characterization of genes specifically expressed in germ line cells
H. Tanaka and Y. Nishimune
Germ Cell Development, Division, Disruption and Death,
B. R. Zirkin, Springer USA, 3-10 (1998) .

Studies on the mechanism of sperm production
H. Tanaka, M. Okabe, M. Ikawa, J. Tsuchida, Y. Yoshimura, K. Yomogida and Y. Nishimune
Testicular Function: From Gene Expression to Genetic Manipulation,
M. Stefanini, C. Boitani, M. Galdieri, R. Geremia and F. Palomibi, Springer-Verlag, New York,235-251 (1998) .

Molecular cloning and characterization of meichroacidin (male meiotic metaphase chromosome-associated acidic protein)
T. Tsuchida, Y. Nishina, N. Wakabayashi, M. Nozaki, Y. Sakai and Y. Nishimune
Dev. Biol., 197, 67-76 (1998).

Molecular cloning of a murine homologue of membrane cofactor protein (CD46): preferential expression in testicular germ cells
A. Tsujimura, K. Shida, M. Kitamura, M. Nomura, J. Takeda, H. Tanaka, M. Matsumoto, K. Matsumiya, A. Okuyama, Y. Nishimune, M. Okabe and T. Seya
Biochem. J., 330, 163-168 (1998).

Acrosin accelerates the dispersal of sperm acrosomal proteins during acrosome reaction
K. Yamagata, M. Murayama, M. Okabe, K. Toshimori, T. Nakanishi, S. Kashiwabara and T. Baba
J. Biol. Chem., 273, 10470-10474 (1998).

The mouse RecA-like gene Dmc1 Is required for homologours chromosome synapsis during meiosis
K. Yoshida, G. Kondoh, Y. Matsuda, T. Habu, Y. Nishimune and T. Morita
Mol. Cell, 1, 707-718 (1998).

光るマウス！？　発光オワンクラゲの遺伝子をマウスで発現　広範な応用に期待
伊川　正人 and 岡部　勝
化学と生物, 36, 140-141 (1998).

哺乳類精巣と精子形成
蓬田　健太郎 and 西宗　義武
蛋白質　核酸　酵素, 43, 511-521 (1998).

新しいマーカータンパク質GFP と緑色の蛍光を出すマウス
岡部　勝
Isotope News, 527, 2-5 (1998).

精細胞の発生分化と遺伝子発現
田中　宏光, 野崎　正美 and 西宗　義武
ホルモンと臨床, 46, 3-14 (1998).
　

Transcriptional activation of a hybrid promoter composed of cytomegalovirus enhancer and beta-actin/beta-globin gene in glomerular epithelial cells in vivo
Y. Akagi, Y. Isaka, A. Akagi, M. Ikawa, M. Takenaka, T. Moriyama, A. Yamauchi, M. Horio, N. Ueda, M. Okabe and E. Imai
Kidney Int., 51, 1265-1269 (1997).

Pyridoxine refractory X-Linked sideroblastic anemia caused by a point mutation in the erythroid 5-aminolevulinate synthase gene.
K. Furuyama, H. Fujita, T. Nagai, K. Yomogida, H. Munakata, M. Kondo, a. Kimura, A. Kuramoto, N. Hayashi and M. Yamamoto
Blood, 90, 822-830 (1997).

Aberrant methylation of an imprinted gene U2af1-rsl (SP2) caused by its own transgene.
I. Hatada, A. Nabetani, Y. Arai, S. Ohishi, M. Suzuki, S. Miyabara, Y. Nishimune and T. Mukai
J. Biol. Chem., 272, 9120-9122 (1997).

Green flourescent protein (GFP) as a marker in transgenic mice.
M. Ikawa and M. Okabe
J. Reprod. Dev., 43, 181-182 (1997).

The putative chaperone calmegin is required for sperm fertility
M. Ikawa, I. Wada, K. Kominami, D. Watanabe, K. Toshimori, Y. Nishimune and M. Okabe
Nature, 387, 607-611 (1997).

Osmolarity in renal medulla of transgenic mice regulates trnscription via 5'-flanking region of canine BGT1 gene.
T. Kaneko, M. Takenaka, M. Okabe, Y. Yoshimura, A. Yamauchi, M. Horio, H. Kwon, J. Handler and E. Imai
Am. J. Physiol., 272, 610-616 (1997).

Cessation of spermatogenesis in juvenile spermatogonial depletion (jsd/jsd) mice.
Y. Kojima, K. Kominami, K. Dohmae, N. Nomura, T. Miki, A. Okuyama, Y. Nishimune and M. Okabe
Int. J. Urol., 4, 500-507 (1997).

Coexpression of multiple sertoli cell and leydig cell marker genes in the spontaneous testicular tumor of F344 rat: Evidence for phenotypical bifurcation of the interstitial cell tumor
G. Kondoh, K. Yomogida, K. Dohmae, M. Nozawa, M. Koga, N. Nonomura, T. Miki, A. Okuyama and Y. Nishimune
Jpn. J. Cancer Res., 88, 839-845 (1997).

Assignment of synaptonemal complex protein 1 (SCP1) to human chromosome 1p13 by fluorescence in situ hybridization and its expression in the testis
N. Kondoh, Y. Nishina, J. Tsuchida, M. Koga, H. Tanaka, K. Uchida, J. Inazawa, M. Taketo, M. Nozaki, H. Nojima, M. K., M. Namiki, A. Okuyama and Y. Nishimune
Cytogenet. Cell Genet., 78, 103-104 (1997).

Mapping of six germ cell-specific genes to mouse chromosomes
M. Matsui, H. Ichihara, S. Kobayashi, H. Tanaka, J. Tsuchida, M. Nozaki, Y. Yoshimura, H. Nojima, J. M. Rochelle, Y. Nihimune, M. M. Taketo and M. F. Seldin
Mammal. Genome, 8, 873-874 (1997).

The regulation of membrane cofactor protein (CD46) expression in transgenic mice: the importance of the first 125 BP of the 3' untranslated region
S. Miyagawa, M. Ikawa, K. Kominami, H. Tanaka, S. Mikata, H. Matsuda, T. Seya, R. Shirakura and M. Okabe
Transplant Proc., 29, 941-942 (1997).

The regulation of membrane cofactor protein (CD46) expression by the 3' untranslated region in transgenic mice
S. Miyagawa, S. Mikata, H. Tanaka, M. Ikawa, K. Kominami, T. Seya, Y. Nishimune, R. Shirakura and M. Okabe
Biochem. Biophys Res. Commun., 233, 829-833 (1997).

Spermatogenesis: Molecular biological approaches.
Y. Nishimune, M. Okabe, H. Tanaka, J. Tsuchida and M. Ikawa
CURRENT ADVANCES IN ANDROLOGY
Proceedings of the VIth International Congress of Andrology, 111-117 (1997).

A study of sperm-egg interaction through transgenic mice.
M. Okabe and M. Ikawa
J. Reprod. Dev., 43, 37-38 (1997).

'Green mice' as a source of ubiquitous green cells
M. Okabe, M. Ikawa, K. Kominami, T. Nakanishi and Y. Nishimune
FEBS Lett., 407, 313-319 (1997).

GATA-1 transcription is controlled by distinct regulatory mechanisms during primitive and definitive erythropoiesis.
K. Onodera, S. Takahashi, s. Nishimura, J. Ohta, H. Motohashi, K. Yomogida, N. Hayashi, L. D. Engel and M. Yamamoto
Proc. Natl., Acad. Sci. USA, 94, 4487-4492 (1997).

Conserved structure, regulatory elements, and transcriptional regulation from the GATA-1 gene testis promoter.
K. Onodera, K. Yomogida, N. Suwabe, S. Takahashi, Y. Muraosa, N. Hayashi, E. Ito, L. GU, M. Rassoulzadegan, J. D. Enge and M. Yamamoto
J. Biochem., 121, 251-263 (1997).

Mapping of eight testis-specific genes to mouse chromosomes
M. M. Taketo, Y. Araki, A. Matsunaga, A. Yokoi, J. Tsuchida, Y. Nishina, M. Nozaki, H. Tanaka, M. Koga, K. Uchida, K. Matsumiya, A. Okuyama, J. M. Rchelle, Y. Nishimune, M. Matsui and M. F. Seldin
Genomics, 46, 138-142 (1997).

Cloning and characterization of the human Calmegin gene encoding putative testis-specific chaperone
H. Tanaka, M. Ikawa, J. Tsuchida, M. Nozaki, M. Suzuki, T. Fujiwara, M. Okabe and Y. Nishimune
Gene, 204, 159-163 (1997).

A germ cell-specific nuclear antigen recognized by monoclonal antibody raised against mouse testicular germ cells.
H. Tanaka, L. A. V. D. Pereira, M. Nozaki, J. Tsuchida, K. Sawda, H. Mori and Y. Nishimune
Int. J. Androl., 20, 361-366 (1997).

Tissue-specific knockout of the mouse Pig-a gene reveals important roles for GPI-anchored proteins in skin development
M. Tarutani, S. Itami, M. Okabe, M. Ikawa, T. Tezuka, K. Yoshikawa, T. Kinoshita and J. Takeda
Proc. Natl. Acad. Sci. USA, 94, 7400-7405 (1997).

ZP3
伊川　正人
ノックアウトマウス・データブック,
黒川 清 and 笹月 健彦, 中山書店, 537-538 (1997) .

GFPに関する情報
伊川　正人 and 岡部　勝
細胞工学, 16, 642-643 (1997).

緑色に光るトランスジェニックマウス-新規マーカーGFP の応用
伊川　正人 and 岡部 勝
細胞工学, 16, 581-587 (1997).

calmegin
岡部　勝 and 西宗　義武
ノックアウトマウス・データブック,
黒川　清 and 笹月　健彦, 中山書店, 68 (1997) .

　

Inhibition of testicular germ cell apoptosis and differentiation in mice misexpressing Bcl-2 in spermatogonia.
T. Furuchi, K. Masuko, Y. Nishimune, M. Obinata and Y. Matsui
Development, 122, 1703-1709 (1996).

The mouse and human homologs of DMC1, the yeast meiosis-specific homologous recomibination gene, have a common unique form of exon-skipped transcript in meiosis.
T. Habu, T. Taki, A. West, Y. Nishimune and T. Morita
Nucl. Acids Res., 24, 470-477 (1996).

Differentiation-dependent enhanced expression of protein phosphatase 2Cbeta in germ cells of mouse seminiferous tubules.
S. Kato, T. Kobayashi, K. Kusuda, Y. Nishina, Y. Nishimune, K. Yomogida, M. Yamamoto, H. Sakagami, H. Kondo, M. Ohnishi, N. Chida, Y. Yanagawa and S. Tamura
FEBS Lett., 396, 293-297 (1996).

Glycosylphosphatidylinositol-anchor-deficient mice: implications for clonal dominance of mutant cells in paroxysmal nocturnal hemoglobinuria
K. Kawagoe, D. Kitamura, M. Okabe, I. Taniuchi, M. Ikawa, T. Watanabe, T. Kinoshita and J. Takeda
Blood, 87, 3600-3606 (1996).

Neoplastic transformation of normal hematopoietic cells by
constitutively activating mutations of c-kit receptor tyrosine kinase.
H. Kitayama, T. Tsujimura, I. Matsumura, K. Oritani, H. Ikeda, J. Ishikawa, M. Okabe, M. Suzuki, K. Yamamura, Y. Matsuzawa, Y. Kitamura and Y. Kanakura
Blood, 88, 995-1004 (1996).

Abrogation of c-kit/Steel factor-dependent tumorigenesis by kinase defective mutants of the c-kit receptor: c-kit kinase defective mutants as candidate tools for cancer gene therapy.
Q. Li, G. Kondoh, S. Inafuku, Y. Nishimune and A. Hakura
Cancer Res., 56, 4343-4346 (1996).

Heast shock induces differentiation of human embryonal carcinoma cells into trophectoderm lineages
T. Maruyama, A. Umezawa, s. Kusakari, H. Kikuchi, M. Nozaki and J. Hata
Exp. Cell. Res., 224, 123-127 (1996).

A receptor tyrosine kinase, Sky, and its ligand Gas 6 are expressed in gonads and support primordial germ cell growth or survival in culture.
N. Matsubara, Y. Takahashi, Y. Nishina, Y. Mukouyama, M. Yanagisawa, T. Watanabe, T. Nakano, K. Nomura, H. Arita, Y. Nishimune, M. Obinata and Y. Matsui
Dev. Biol., 180, 499-510 (1996).

Difference of expression levels between gene technological product delta CYT-MCP(CD46) and intact MCP(CD46) in transgenic mice
S. Miyagawa, M. Ikawa, K. Kominami, Y. Yoshimura, H. Tanaka, S. Mikata, R. Shirakura, H. Matsuda, Y. Yanagi, T. Seya and M. Okabe
Transplant Proc., 28, 585-586 (1996).

In vitro and in vivo studies to prevent hyperacute rejection
S. Miyagawa, M. Mikata, H. Matsuda, M. Ikawa, M. Okabe, S. Nagasawa, M. Matsumoto, T. Seya and R. Shirakura
Transplant Proc., 28, 1031-1033 (1996).

Molecular cloning of EIK-3, a new member of the Ets family expressed during mouse embryogenesis and analysis of its transcriptional repression activity
M. Nozaki, Y. Onishi, N. Kanno, Y. Ono and Y. Fujimura
DNA Cell. Biol., 15, 855-862 (1996).

Molecular characterization of the Drosophila Mo25 gene, which is conserved among Drosophila, mouse, and yeast
M. Nozaki, Y. onishi and H. Miyamoto
DNA Cell. Biol., 15, 505-509 (1996).

Involvement of transcription factor encoded by the milocus in the expression of c-kit receptor tyrosine kinase in cultured mast cells of mice
T. Tsujimura, E. Morii, M. Nozaki, K. Hashimoto, Y. Moriyama, K. Takebayashi, T. Kondo, Y. Kanakura and Y. Kitamura
Blood, 88, 1225-1233 (1996).

Targeted disruption of the Rad51 gene leads to lethaliy in embryonic mice.
T. Tsuzuki, Y. Fujii, K. Sakumi, Y. Tominaga, K. Nakao, M. Sekiguchi, A. Matsushiro, Y. Yoshimura and T. Morita
Proc. Natl. Acad. Sci. USA, 93, 6236-6240 (1996).

Cell cycle-dependent expression of the mouse Rad51 gene in proliferating cells.
A. Yamamoto, T. Taki, H. Yagi, T. Habu, K. Yoshida, Y. Yoshimura, K. Yamamoto, A. Matsushiro, Y. Nishimune and T. Morita
Mol. Gen. Gent., 251, 1-12 (1996).

動物実験を行うときに知っておくべきこと
岡部　勝
新生物化学実験のてびき,
下西　康嗣, 永井　克也, 長谷　俊治 and 本田　武司, （株）化学同人, 京都市,1-15 (1996) .

　

Isolation of a novel cDNA that encodes a protein localized to the pre-acrosome region of spermatids.
H. Aoto, J. Tsuchida, Y. Nishina, Y. Nishimune, A. Asano and S. Tajima
Eur. J. Biochem., 234, 8-15 (1995).

Protection against hantavirus infection by dam's immunity transferred vertically to neonates.
K. Dohmae and Y. Nishimune
Arch. Virol., 140, 165-172 (1995).

Induction of teratocarcinoma F9 cell differentiation with cis-diammine dichloroplatinum (II) (CDDP).
T. Doi, T. Sumi, Y. Nishina, M. Kosaka, S. Iwai, M. Sakuda and Y. Nishimune
Cancer Letters, 88, 81-86 (1995).

Green fluorescent protein as a maker in transgenic mice.
M. Ikawa, K. Kominami, Y. Yoshimura, K. Tanaka, Y. Nishimune and M. Okabe
Develop. Growth Differ., 37, 455-459 (1995).

A rapid and non-invasive selection of transgenic embryos before implantation using green fluorescent protein (GFP)
M. Ikawa, K. Kominami, Y. Yoshimura, K. Tanaka, Y. Nishimune and M. Okabe
FEBS Lett., 375, 125-128 (1995).

Improvement of fusing ability of human sperm to zona-free hamster eggs by conditioned media
M. Ikawa, X. Ying, K. Tanaka, K. Ohashi, F. Saji and M. Okabe
Biol. Pharm. Bull., 18, 5-8 (1995).

The kinetics of induction of Hox1.6 and c-jun mRNA during three different ways of inducing differentiation in teratocarcinoma F9 cells.
S. Iwai, Y. Nishina, M. Kosaka, T. Sumi, T. Doi, M. Sakuda and Y. Nishimune
In Vitro Cell. Dev. Biol., 31, 462-466 (1995).

Diversity of sites for measles virus binding and for inactivation of complement C3b and C4b on membrane cofactor protein CD46
K. Iwata, T. Seya, Y. Yanagi, J. M. Pesando, P. M. Johnson, M. Okabe, S. Ueda, H. Ariga and S. Nagasawa
J. Biol. Chem., 270, 15148-15152 (1995).

Membrane cofactor protein (CD46) in seminal plasma is a prostasome-bound form with complement regulatory activity and measles virus neutralizing activity
M. Kitamura, M. Namiki, K. Matsumiya, K. Tanaka, M. Matsumoto, T. Hara, H. Kiyohara, M. Okabe, A. Okuyama and T. Seya
Immunology, 84, 626-632 (1995).

An in vivo model for receptor tyrosine kinase autocrine/paracrine activation: auto-stimulated KIT receptor acts as a tumor promoting factor in papillomavirus-induced tumorigenesis.
G. Kondoh, N. Hayasaka, Q. Li, Y. Nishimune and A. Hakura
Oncogene, 10, 341-347 (1995).

Characterization of a novel spermatogenic cell antigen specific for early stages of germ cells in mouse testis.
U. Koshimizu, H. Nishioka, D. Watanabe, K. Dohmae and Y. Nishimune
Mol. Reprod. Dev., 40, 221-227 (1995).

Murine polo like kinase 1 gene is expressed in meiotic testicular germ cells and oocytes.
N. Matsubara, M. Yanagisawa, Y. Nishimune, M. Obinata and Y. Matsui
Mol. Reporod. Deve., 41, 407-415 (1995).

Hinokitiol induces differentiation of teratocarcinoma F9 cells.
N. Muto, A. Dota, T. Tanaka, N. Itoh, M. Okabe, A. Inada, T. Nakanishi and K. Tanaka
Biol. Pharm. Bull., 18, 1576-1579 (1995).

High incidence of ultraviolet-B-or chemical-carcinogen-induced skin tumours in mice lacking the xeroderma pigmentosum group A gene.
H. Nakane, S. Takeuchi, S. Yuba, M. Saijo, Y. Nakatsu, H. Murai, Y. Nakatsuru, T. Ishikawa, S. Hirota, Y. Kitamura, Y. Kato, Y. Tsunoda, H. Miyauchi, T. Horio, T. Tokunaga, T. Matsunaga, O. Nikaido, Y. Nishimune, Y. Okada and K. Tanaka
Nature, 377, 165-168 (1995).

Effects of protein phosphatase inhibition by Okadaic acid on the differentiation of F9 embryonal carcinoma cells.
Y. Nishina, T. Sumi, S. Iwai and Y. Nishimune
Exp. Cell. Res., 217, 288-293 (1995).

Cloning and sequencing of the gene coding for dextranase from Streptococcus salivarius
Y. Ohnishi, S. Kubo, Y. Ono, M. Nozaki, Y. Gonda, H. Okano, T. matsuya, a. matsushiro and T. Morita
Gene, 156, 93-96 (1995).

Insulin-like growth factor-l and transforming growth factor-a stimulate differentiation of type A spematogonia in organ culture of adult mouse cryptorchid testes.
Y. Tajima, D. Watanabe, U. Koshimizu, T. Matsuzawa and Y. Nishimune
Int. J. Androl., 18, 8-12 (1995).

Mouse EIK oncogene maps to chromosome X and a novel EIK oncogen (EIK3) maps to chromosome 10
Y. Tamai, M. Taketo, M. Nozaki and M. Seldin
Genomics, 26, 414-416 (1995).

Role of HU proteins in forming and constraining supercoils of chromosomal DNA in escherichia coli.
H. Tanaka, K. Yasuzawa, K. Kohno, N. Goshima, Y. Kano, T. Saiki and F. Imamoto
Mol. Gen. Genet., 248, 518-526 (1995).

Characterization of development-specific, cell type-specific mouse testicular antigens using testis-specific polyclonal antibodies.
J. Tsuchida, Y. Nishina, T. Akamatsu and Y. Nishimune
Int. J. Andorol., 18, 208-212 (1995).

Characterization of the testis-specific gene 'calmegin' promoter sequence and its activity defined by transgenic mouse experiments
D. Watanabe, M. Okabe, N. Hamajima, T. Morita, Y. Nishina and Y. Nishimune
FEBS Lett., 368, 509-512 (1995).

Regulaltion of the mouse histone H2A.X gene promoter by the transcription factor E2F and CCAAT binding protein
H. Yagi, T. Kato, T. Nagata, T. Habu, M. Nozaki, A. Matsushiro, Y. Nishimune and T. Morita
J. Biol. Chem., 270, 18759-18765 (1995).

Regulation of the mouse histone H2.AX Gene Promoter by the transcription factor and CCAAT binding protein.
H. Yagi, T. Kato, T. Nagata, T. Habu, M. Nozaki, A. Matsushiro, Y. Nishimune and T. Morita
J. Biol. Chem., 270, 18759-18765 (1995).

受精とcapacitation
岡部　勝
臨床科学, 8, 1035-1043 (1995).

発生工学の誕生
岡部　勝
病気のバイオサイエンス,
大阪大学微生物病研究所, 117-127 (1995) .

精細胞の増殖と分化
田中　宏光, 仁科　行雄, 土田　順司 and 西宗　義武
組織培養, 21, 278-282 (1995).

精細胞の増殖と分化
土田　順司, 仁科　行雄 and 西宗　義武
臨床科学, 31, 475-483 (1995).

ラットにおけるハンタウイルスの伝播と移行抗体の働きについて
堂前　嘉代子 and 西宗　義武
臨床とウイルス, 23, 1-5 (1995).
　

Experimental transmission of hantavirus infection in laboratory rats
K. Dohmae, M. Okabe and Y. Nishimune
J. Infect. Dis., 170, 1589-1592 (1994).

One of two Ets-binding sites in the cytokeratin EndoA enhancer is essential for enhancer activity and binds to Ets-2 related proteins
Y. Fujimura, H. Yamamoto, F. Hamazato and M. Nozaki
Nucleic. Acids. Res., 22, 613-618 (1994).

IHF supresses the inhibitory effect of H-NS on HU function in the hin inversion system
N. Goshima, Y. Kano, H. Tanaka, K. Kohno, T. Iwaki and F. Imamoto
Gene, 141, 17-23 (1994).

Cell type-specific deficiency of c-kit gene expression in mutant mice of mi/mi genotype.
K. Isozaki, T. Tsujimura, S. Nomura, E. Morii, U. Koshimizu, Y. Nishimune and Y. Kitamura
Amer. J. Pathol., 145, 827-836 (1994).

n- Hexane-induced synthesis of hepatic metallothionein is mediated by IL-6 in mouse.
N. Itoh, H. Okamoto, M. Ohta, T. Hori, K.-S. Min, S. Onosaka, H. Nakanishi, M. Okabe, N. Muto and K. Tanaka
Toxicol. Appl. Pharmacol., 124, 257-261 (1994).

Autoregulation of transcription of the hupA gene in Escherichia coli: evidence for steric hindrance of the functional promoter domains induced by HU
K. Kohno, K. Yasuzawa, M. Hirose, Y. Kano, N. Goshima, T. H. and F. Imamoto
J. Biochem., 115, 1113-1118 (1994).

Establishment and further characterization of a line of transgenic mice showing testicular tumorigenesis at 100% incidence.
G. Kondoh, Y. Nishimune, Y. Nishizawa, N. Hayasaka, K. Matsumoto and A. Hakura
J. Virol., 152, 2151-2154 (1994).

F9 cells can be differentiated toward two distinct, mutually exclusive pathways by retinoic acid and sodium butyrate.
M. Kosaka, M. Takeda, K. Matsumoto and Y. Nishimune
Develop. Growth. & Differ., 32, 223-230 (1994).

Wn mutation of c-kit receptor affects its post-translational processing and extracellular expression.
U. Koshimizu, T. Tsujimura, K. Isozaki, S. Nomura, T. Furitsu, Y. Kanakura, Y. Kitamura and Y. Nishimune
Oncogene, 9, 157-162 (1994).

Activation of the mouse cytokeratin A (endo A) gene in teratocarcinoma F9 cells by the histone deacetylase inhibitor Trichostatin A.
T. Miyashita, H. Yamamoto, Y. Nishimune, M. Nozaki, T. Morita and A. Matsushiro
FEBS Lett., 353, 225-229 (1994).

The complete sequence of the gene encoding mouse cytokeratin 15
M. Nozaki, M. Mori and A. Matsushiro
Gene, 138, 197-200 (1994).

Selection of acrosome-reacted sperm with MH61-Immunobeads.
K. Ohashi, F. Saji, A. Wakimoto, T. Tsutsui, T. Nakazawa, M. Okabe, T. Mimura and O. Tanizawa
J. Andrology, 15, 78-82 (1994).

Switching of mouse spermatogonial proliferation from the c-kit receptor-independent type to the receptor-dependent type during differentiation.
Y. Tajima, K. Sawada, T. Morimoto and Y. Nishimune
J. Reprod. Fertil., 102, 117-122 (1994).

Isolation and characterization of cDNA clones specifically expressed in testicular germ cells.
H. Tanaka, Y. Yoshimura, Y. Nishina, M. Nozaki, H. Nojima and Y. Nishimune
FEBS Lett., 355, 4-10 (1994).

Molecular cloning of a novel Ca2+-binding protein (Calmegin) specifically expressed during male Meiotic germ cell development.
D. Watanabe, K. Yamada, Y. Nishina, Y. Tajima, U. Koshimizu, A. Nagata and Y. Nishimune
J. Biol. Chem., 269, 7744-7749 (1994).

Developmental stage- and spermatogenic cycle-specific expression of transcription factor GATA-1 in mouse Sertoli cells.
K. Yomogida, H. Ohtani, H. Harigae, E. Ito, Y. Nishimune, J. D. Engel and M. Yamamoto
Development, 120, 1759-1766 (1994).

造血幹細胞の多様性と寿命
木下　タロウ, 西宗　義武, 中内　啓光 and 吉田　尚弘
Mol. Medicine., 31, 1122-1140 (1994).

幹細胞活性化の多様性
西宗　義武
Mol. Medicine, 31, 1096-1103 (1994).

マウス精巣における支持細胞の働き
田島　陽一 and 西宗　義武
細胞, 26, 344-349 (1994).
　

In utero and mammary transfer of Hantavirus antibody from dams to infant rats.
K. Dohmae, U. Koshimizu and Y. Nishimune
Lab. Anim. Sci., 43, 557-561 (1993).

Degeneration of skeletal and cardiac muscles in c-myb transgenic mice.
Y. Furuta, S. Aizawa, Y. Suda, Y. Ikawa, H. Nakasgoshi, Y. Nishina and S. Ishii
Trans. Res., 2, 199-207 (1993).

Sequence specific binding of Ets-1 to the mouse cytokeratin EndoA gene enhacer
F. Hamazato, Y. Fujimura, Y. Tamai, Y. Takemoto, A. Matsushiro and M. Nozaki
Biohem. Biophys. Res. Commun., 192, 430-438 (1993).

Changes in Hox1.6, c-jun, and Oct-3 gene expressions are associated with teratocarcinoma F9 cell differentiation in three different ways of induction.
S. Iwai, M. Kosaka, Y. Nishina, T. Sumi, M. Sakuda and Y. Nishimune
Exp. Cell. Res., 205, 39-43 (1993).

Propagation of phage Mu in IHF-deficient Escherichia coli in the absence of the H-NS histone-like protein
Y. Kano, K. Yasuzawa, H. Tanaka and F. imamoto
Gene, 126, 93-97 (1993).

Infection of Nippostrongylus Brasiliensis induces normal increase of basophils in mast cell-deficient Ws/Ws rats with a small deletion at the kinase domain of c-kit.
T. Kasugai, M. Okada, M. Morimoto, N. Arizono, K. Maeyama, M. Yamada, H. Tei, K. Dohmae, H. Onoue, G. F. J. Newlands, T. Watabe, Y. Nishimune, H. R. P. Miller and Y. Kitamura
Blood, 81, 2521-2529 (1993).

Roles of c-kit receptor and its ligand for germ cell differentiation.
Y. Kitamura, T. Kasugai, H. Nakayama, S. Nomura and Y. Nishimune
Biology of the germ line, edited,
H. Mohri, M. Takahashi and C. Tachi, Japan Scientific Societies Press, Karger, 51-62 (1993) .

Structure of the gene encoding rat neutrophil chemo-attractant.
K. Konishi, Y. Takada, M. Yamamoto, K. Yomogida, K. Watanabe, S. Tsurumaki and M. Fujioka
Gro. Gene, 126, 285-286 (1993).

A novel stage-specific differentiation antigen is expressed on mouse testicular germ cells during early meiotic prophase.
U. Koshimizu, D. Watanabe, K. Sawada and Y. Nishimune
Biol. Reprod., 49, 875-884 (1993).

Identification of differentiation-dependent DNase I-hypersensitive in the mous EndoA gene
H. Miyamamoto, Y. Takemoto, M. Nozaki, T. Morita and A. Matsushiro
Gene, 125, 151-158 (1993).

Molecular cloning of a novel mRNA sequence expressed in cleavage stage mouse embryos
H. Miyamoto, A. Matsushiro and M. Nozaki
Mol. Reprod. Dev., 34, 1-7 (1993).

Hormonal Regulation of Human Testicular Inhibin a and bB Subunit Messenger RNAs.
M. Namiki, N. Kondoh, K. Matsumiya, S. Sakoda, Y. Nishimune and A. Okuyama
J. Urol., 150, 1007-1009 (1993).

Mammalian male gametogenesis: Growth, differentiation and maturation of germ cells.
Y. Nishimune and M. Okabe
Develop. Growth & Differ., 35, 479-486 (1993).

The induction of jun genes during the reversible changes induced with sodium butyrate on the differentiation of F9 cells.
Y. Nishina, T. Sumi, S. Iwai, M. Kosaka and Y. Nishimune
Exp. Cell. Res., 208, 492-497 (1993).

An enhancer unit of L-type pyruvate kinase gene is responsible for transcriptional stimulation by dietary fructose as well as glucose in trasgenic mice.
T. Noguchi, M. Okabe, Z. Wang, K. Yamada, E. Imai and T. Tanaka
FEBS Lett., 318, 269-272 (1993).

Characterization of capacitation inhibitory protein from rabbit seminal plasma: homology with human annexins.
M. Okabe, Y. Kishi, X. Ying, Y. Kohama, T. Mimura and S. S.-L. Li
Bio. Pharm. Bull., 16, 453-456 (1993).

Homology of an acrome-reacted sperm-specific antigen to membrane cofactor protein.
M. Okabe, H. Takahashi, X. Ying, M. Ikawa and T. Seya
Jap. Soc. Immun. Reprod., 7, 100-103 (1993).

Selection of acrosome-reacted human sperm and their fusing ability by microinjection into perivitelline space of hamster eggs.
M. Okabe, X. Ying and T. Mimura
Human. Reprod., 8, 1074-1078 (1993).

Membrane cofactor protein (MCP, CD46) in seminal plasma and on spermatozoa in normal and "sterile" subjects
T. Seya, T. Hara, M. Matsumoto, H. Kiyohara, I. Nakanishi, T. Kinouchi, M. Okabe, A. Shimizu and H. Akedo
Eur. J. Immunol., 23, 1322-7 (1993).

Suppression of tumorigenicity in temperature-sensitive mutants of embryonal carcinoma cells by induction of cell differentiation at nonpermissive temperature.
T. Sumi, Y. Nishina, M. Kosaka, M. Sakuda and Y. Nishimune
Int. J. Cancer., 54, 333-337 (1993).

Effects of hormones, cyclic AMP analogues, and growth factors on steel factor (SF) production in mouse Sertoli cell cultures.
Y. Tajima, Y. Nishina, Y. Koshimizu, T. Jippo, Y. Kitamura and Y. Nishimune
J. Reprod. Fertil., 99, 571-575 (1993).

Effects of W and Sl Gene on Germ Cell Differentiation.
Y. Tajima, K. Sawada and Y. Nishimune
Proceedings of the Japanese Society of Animal Models for Human Diseases, 9, 15-18 (1993).

Properties of DNA-binding of HU heterotypic and homotypic dimers from Escherichia coli
H. Tanaka, N. Goshima, K. Kohno and F. Imamoto
J. Biochem., 113, 568-572 (1993).

Mast cell number in the skin of heterozygotes reflects the molecular nature of c-Kit mutation.
T. Tsujimura, U. Koshimizu, H. Katoh, K. Isozaki, Y. Kanakura, T. Tono, S. Adachi, T. Kasugai, H. Tei, Y. Nishimune, S. Nomura and Y. Kitamura
Blood, 81, 2530-2538 (1993).

Selection of acrosome-reacted human spermatozoa and their fusing ability by micro-injection into the perivitelline space of hamster eggs
X. Ying, M. Okabe and T. Mimura
Hum. Reprod., 8, 1074-1078 (1993).

Structure and expression of the gene encoding rat nonspecific form d-aminolevulinate synthase.
K. Yomogida, M. Yamamoto, T. Yamagami, H. Fujita and N. Hayashi
J. Biochem., 133, 364-371 (1993).

精子は何を認識して融合を起こすのか
伊川　正人 and 岡部 勝
生化学, 65, 1429-33 (1993).

精子形成におけるSl 因子c-kit レセプターのはたらき -変異マウスを用いた解析を中心に
小清水　右一 and 西宗　義武
実験医学, 11, 28-34 (1993).

受精のメカニズム-精子の受性能獲得
岡部　勝
産科と婦人科, 60, 1413-1417 (1993).

受精と接着分子
瀬谷　司 and 岡部　勝
臨床免疫, 25, 1150-1158 (1993).

新しい精子機能検査としてのアクロビ-ズテスト
大橋　一友, 佐治　文隆, 谷沢　修, 鈴木　佳彦, 宮崎　和典, 杉本　修, 松岡　逸子, 藤野　祐司, 荻野　幸雄, 後藤　康夫, 森　崇英, 石川　元春, 星合, 野田　起一郎, 野田　洋一, 池田　義和, 亀田　絹, 磯島　晋三, 三村　務 and 岡部　勝
産婦人科の世界, 45, 859-862 (1993).

特集：腎症候性出血熱(HFRS); 最近の話題
腎症候性出血熱ウイルスの実験ラットにおける伝播様式について
堂前　嘉代子 and 西宗　義武
アニテックス, 5, 290-293 (1993).
　

Chimeric HU-IHF proteins that alter DNA-binding ability
N. Goshima, Y. Inagaki, H. Otaki, H. Tanaka, N. Hayashi, F. Imamoto and Y. Kano
Gene, 118, 97-102 (1992).

Amino acid substitution in the C-terminal arm domain of HU-2 results in an enhanced affinity for DNA
N. Goshima, Y. Kano, H. Tanaka, K. Kohono, K. Yasuzawa and F. Imamoto
Gene, 121, 121-126 (1992).

Mast cell-deficient mice and rats
T. Kasugai, Y. Niwa, Y. Ebi, Y. Nishimune, K. Kondo and Y. Kitamura
Molecular Approaches to the Study and Treatment of Human Diseases,
T. O. Yoshida and J. M. Wilson, Elsevier Science, 309-313 (1992) .

Inhibitory effects of bis(2-aminohexyl)disulfide and its analogues on polymorphonuclear leukocyte functions in vitro
Y. Kohama, Y. Kayamori, Y. Katayama, T. Teramoto, N. Murayama, K. Tsujikawa, M. Okabe, T. Ohtani, T. Matsukura and T. Mimura
Chem. Pharm. Bull. Tokyo, 40, 414-418 (1992).

Preparation of biologically active and site specifically radioiodinated recombinant human insulin-like growth factor-I
Y. Kohama, M. Okabe, K. Tsujikawa, H. Oka, T. Teramoto, Y. Kayamori, M. Itoh and T. Mimura
Chem. Pharm. Bull. Tokyo, 40, 808-810 (1992).

c-myc and p53 gene expression in the differentiation of temperature-sensitive mutants of teratocarcinoma F9 cells.
M. Kosaka, S. Iwai, Y. Nishina, T. Sumi and Y. Nishimune
Oncogene, 7, 2455-2460 (1992).

Effects of W (c-kit) gene mutation on gametogenesis in male mice: agametic tubular segments in Wf/Wf testes
U. Koshimizu, D. Watanabe, Y. Tajima and Y. Nishimune
Development, 114, 861-867 (1992).

Nucleotide sequence of a mouse Tcp-1 pseudogene: a nucleotide record for a t complex gene carried by an ancestor of the mouse
H. Kubota, T. Morita, Y. Satta, M. Nozaki and A. Matsushiro
Mamm. Genome., 2, 246-251 (1992).

Structure and expression of the gene encoding mouse t-complex polypeptide (Tcp-1)
H. Kubota, K. Willison, A. Ashworth, M. Nozaki, H. Miyamoto, H. Yamamot, A. Matsushiro and T. Morita
Gene, 120, 207-215 (1992).

Loss of sperm in juvenile spermatogonial depletion (jsd) mutant mice is ascribed to a defect of intratubular environment to support germ cell differentiation
M. Mizunuma, K. Dohmae, Y. Tajima, U. Koshimizu, D. Watanabe and Y. Nishimune
J. Cell. Physiol., 150, 188-193 (1992).

Spatial expression of genes encoding c-kit receptors and their ligands in mouse cerebellum as revealed by in situ hybridization
E. Morii, S. Hirota, H. Kim, K. Mikoshiba, Y. Nishimune, Y. Kitamura and S. Nomura
Dev. Brain. Res., 65, 123-126 (1992).

Evolution of the mouse t haplotype: recent and worldwide introgression to Mus musculus
T. Morita, H. Kubota, K. Murata, M. Nozaki, C. Delarbre, W. K., Y. Satta, M. sakazumi, N. Takahata and G. Gachelin
Proc. Natl. Acad. Sci. USA, 1992, 15 (1992).

Expression of c-kit protooncogene is stimulated by cAMP in differentiated F9 mouse teratocarcinoma cells
Y. Nishina, Y. Kobarai, T. Sumi, M. Kosaka, S. Nishikawa and Y. Nishimune
Exp. Cell. Res., 198, 352-356 (1992).

Evaluation of acrosomal status using MH61-beads test and its clinical application
K. Ohashi, F. Saji, M. Kato, M. Okabe, T. Mimura and O. Tanizawa
Fertil. Steril., 58, 803-808 (1992).

Collection of acrosome-reacted human sperm using monoclonal antibody-coated paramagnetic beads
M. Okabe, S. Matzno, M. Nagira, X. Ying, Y. Kohama and T. Mimura
Mol. Reprod. Dev., 32, 389-393 (1992).

Homology of an acrosome-reacted sperm-specific antigen to CD46
M. Okabe, X. Ying, M. Nagira, M. Ikawa, Y. Kohama, T. Mimura and K. Tanaka
J. Pharmacobiodyn., 15, 455-459 (1992).

Teratocarcinoma F9 cells induced to differentiate with sodium butyrate produce both tissue-type and urokinase-type plasminogen activators.
M. Takeda, M. Kosaka, Y. Nishina, K. Sawada, K. Matsumoto and Y. Nishimune
J. Cell. Biochem., 49, 284-289 (1992).

c-kit gene was not transcribed in cultured mast cells of mast cell-deficient Wsh/Wsh mice that have a normal number of erythrocytes and a normal c-kit coding region
T. Tono, T. Tsujimura, U. Koshimizu, T. Kasugai, S. Adachi, K. Isozaki, S. Nishikawa, M. Morimoto, Y. Nishimune, S. Nomura and Y. Kitamura
Blood, 80, 1448-1453 (1992).

Characterization of male meiotic germ cell-specific antigen (Meg 1) by monoclonal antibody TRA 369 in mice.
D. Watanabe, K. Sawada, U. Koshimizu, T. Kagawa and Y. Nishimune
Mol. Reprod. Dev., 33, 307-.12. (1992).

精子の受精能獲得
岡部　勝 and 柳町隆造
精子学,
毛利秀雄, 東大出版会, 152-167 (1992) .
　

Differential effects of epidermal growth factor on the differentiation of type A spermatogonia in adult mouse cryptorchid testes in vitro
T. Haneji, S. Koide, Y. Tajima and Y. Nishimune
J. Endocrinol., 128, 383-8 (1991).

Reversible effects of sodium butyrate on the differentiation of F9 embryonal carcinoma cells.
M. Kosaka, Y. Nishina, M. Takeda, K. Matsumoto and Y. Nishimune
Exp Cell Res., 192, 46-51 (1991).

White-spotting mutations affect the regenerative differentiation of testicular germ cells: demonstration by experimental cryptorchidism and its
surgical reversal.
U. Koshimizu, K. Sawada, Y. Tajima, D. Watanabe and Y. Nishimune
Biol Reprod., 45, 642-8 (1991).

In-vitro proliferation of germ cells and supporting cells in the neonatal mouse testis
M. Maekawa and Y. Nishimune
Cell Tissue Res, 265, 551-4 (1991).

Anemia and mast cell depletion in mutant rats that are homozygous at "white spotting (Ws)" locus.
Y. Niwa, T. Kasugai, K. Ohno, M. Morimoto, M. Yamazaki, K. Dohmae, Y. Nishimune, K. Kondo and Y. Kitamura
Blood., 78, 1936-41. (1991).

Anemia and mast cell depletion in mutant rats that are homozygous at "white spotting (Ws)" locus
Y. Niwa, T. Kasugai, K. Ohno, M. Morimoto, M. Yamazaki, K. Dohmae, Y. Nishimune, K. Kondo and Y. Kitamura
Blood, 78, 1936-41 (1991).

Selection and microinjection of human sperm into perivitelline space of hamster eggs
M. Okabe, X. Ying and T. Mimura
Jap. Soc. Basic Reprod. Immunol., 6, 151-153 (1991).

Effect of the W mutation, for white belly spot, on testicular germ cell differentiation in mice
K. Sawada, K. Sakamaki and Y. Nishimune
J. Reprod. Fertil., 93, 287-94 (1991).

Biologically active kit ligand growth factor is produced by mouse Sertoli cells and is defective in SId mutant mice
Y. Tajima, H. Onoue, Y. Kitamura and Y. Nishimune
Development, 113, 1031-5 (1991).

Steel-Dickie (Sld) mutation affects both maintenance and differentiation of testicular germ cells in mice
Y. Tajima, K. Sakamaki, D. Watanabe, U. Koshimizu, T. Matsuzawa and Y. Nishimune
J. Reprod. Fertil., 91, 441-9 (1991).

Characterization of Ws mutant allele of rats: a 12-base deletion in tyrosine kinase domain of c-kit gene
T. Tsujimura, S. Hirota, S. Nomura, Y. Niwa, M. Yamazaki, T. Tono, E. Morii, H. M. Kim, K. Kondo, Y. Nishimune and Y. Kitamura
Blood, 78, 1942-6 (1991).

Cyclic localization change of Golgi apparatus in Sertoli cells induced by mature spermatids in rats
H. Ueno, Y. Nishimune and H. Mori
Biol. Reprod., 44, 656-62 (1991).
　

Angiotensin-converting enzyme inhibitor cut out of yeast glyceraldehyde -3-phosphate dehydrogenase
Y. Kohama, T. Nakagawa, H. Oka, N. Murayama, K. Tsujikawa, M. Okabe and T. Mimura
J. Pharmacobio-Dyn, 13, s-36 (1990).

Testicular macromolecular synthesis in men with varicocele
M. Nakamura, E. Koh, N. Kondoh, M. Takeyama, M. Namiki, H. Fujioka, H. Kiyohara, Y. Nishimune, A. Okuyama and T. Sonoda
Arch. Androl., 24, 69-72 (1990).

An attempt to evaluate human sperm fertilizing ability with a monoclonel antibody
M. Okabe, S. Matsuno, X. Ying, M. Nagira, Y. Kohama and T. Mimura
Serono Symposia, USA, Norwell, Mass., 432 (1990).

A human sperm antigen possibly involved in binding and/or fusion with zona-free hamster eggs
M. Okabe, M. Nagira, Y. Kawai, S. Matzno, T. Mimura and T. Mayumi
Fertil Steril, 54, 1121-6 (1990).

A preliminry study for the selection of fertilizing human sperm
M. Okabe, X. Ying, M. Nagira, H. Umeki, H. Takahashi and T. Mimura
Jap. Soc. Basic Reprod. Immunol., 5, 77-80 (1990).
　

Flow cytometric analysis of mouse sperm using monoclonal anti-sperm antibody OBF13
Y. Kawai, T. Hama, T. Mayumi, M. Okabe, S. Matzno, Y. Kohama and T. Mimura
J Reprod Immunol, 16, 71-82 (1989).

Identification of angiotensin-converting enzyme inhibitory peptide in fish tissues
Y. Kohama, S. Matsumoto, H. Oka, T. Teramoto, M. Okabe and T. Mimura
Peptide Chemistry, 1988, 15-20 (1989).

Enhancement of heparin-binding ability of fibronectin by S-carboxamide-methylation
Y. Kohama, T. Miyamoto, H. Oka, K. Yamamoto, N. Murayama, K. Tsujikawa, M. Okabe and T. Mimura
J Pharmacobiodyn, 12, 626-33 (1989).

Induction of angiotensin-converting enzyme inhibitory activity by acid-limited proteolysis of glyceraldehyde 3-phosphate dehydrogenase
Y. Kohama, H. Oka, K. Yamamoto, T. Teramoto, M. Okabe, T. Mimura, Y. Nagase, Y. Chiba and T. Fujita
Biochem Biophys Res Commun, 161, 456-60 (1989).

Differentiation of germ cells in seminiferous tubules transplanted to testes of germ cell-deficient mice of W/Wv and Sl/Sld genotypes
H. Kuroda, H. Nakayama, M. Namiki, K. Matsumoto, Y. Nishimune and Y. Kitamura
J. Cell. Physiol., 139, 329-34 (1989).

Plasminogen activator secreted by Sertoli cells in response to retinoids.
M. Maekawa, K. Sakamaki, K. Sawada and Y. Nishimune
Mol. Androl., 1, 331-336 (1989).

The inhibitory effect of bis[2-[(E)-2-octenoylamino]ethyl] disulfide on the cyclooxygenase pathway
T. Mimura, H. Nakajima, K. Tsujikawa, N. Yasuda, M. Haruyama, M. Okabe, M. Iwai and K. Yokoyama
Chem Pharm Bull Tokyo, 37, 778-80 (1989).

Studies on pharmacological activation of human serum immunoglobulin G by chemical modification and active subfragments. VIII. Effect of carboxamide-methylated light chain (Fr.I-L) on leukocyte functions
T. Mimura, K. Tsujikawa, N. Yasuda, H. Nakajima, B. G. Lee, M. Okabe and Y. Kohama
J Pharmacobiodyn, 12, 159-63 (1989).

Impairment of testicular DNA synthesis in infertile men
M. Nakamura, N. Nonomura, E. Koh, N. Kondoh, M. Namiki, H. Fujioka, H. Kiyohara, Y. Nishimune, K. Matsumoto and A. Okuyama
Mol. Androl., 2, 35-43 (1989).

Flow cytometric evaluation of temperature-induced spermatogenic damage
M. Nakamura, N. Nonomura, E. Koh, N. Kondoh, M. Namiki, H. Fujioka, H. Kiyohara, Y. Nishimune and A. Okuyama
Mol. Androl., 2, 45-52 (1989).

DNA and RNA synthesis by postpubertal undescended testis in vitro.
M. Nakamura, N. Nonomura, M. Namiki, A. Okuyam, E. Koh, N. Kondoh, H. Fujioka, Y. Nishimune, K. Matsumoto and M. M.
Arch Androl., 22, 91-4. (1989).

DNA and RNA synthesis by postpubertal undescended testis in vitro
M. Nakamura, N. Nonomura, M. Namiki, A. Okuyama, E. Koh, N. Kondoh, H. Fujioka, Y. Nishimune, K. Matsumoto and M. Matsuda
Arch. Androl., 22, 91-4 (1989).

Temperature sensitivity of spermatids in men with varicocele
M. Nakamura, N. Nonomura, M. Namiki, A. Okuyama, E. Koh, N. Kondoh, H. Kiyohara, Y. Nishimune, K. Matsumoto, E. Nakano and M. Matsuda
Mol. Androl., 1, 165-172 (1989).

Impaired DNA synthesis by early pubertal cryptorchid testis in vitro
M. Nakamura, N. Nonomura, M. Namiki, A. Okuyama, E. Koh, N. Kondoh, M. Takeyama, H. Fujioka, H. Kiyohara, Y. Nishimune and a. l. et
Arch. Androl., 22, 137-41 (1989).

Inhibition of DNA synthesis causes stem cell differentiation: induction of teratocarcinoma F9 cell differentiation with nucleoside analogues of DNA-synthesis inhibitors and their inducing abilities counterbalanced specifically by normal nucleosides
Y. Nishimune, M. Kosaka, Y. Nishina, T. Sumi, M. Sakuda, M. Takeda and K. Matsumoto
Biochem. Biophys. Res. Commun., 163, 1290-7 (1989).

Isolation of mutants showing temperature-sensitive cell growth from embryonal carcinoma cells: control of stem cell differentiation by incubation temperatures
Y. Nishimune, Y. Nishina, T. Sumi, M. Kosaka, M. Takeda, K. Matsumoto, A. Matsushiro and M. Sakuda
Biochem. Biophys. Res. Commun., 165, 65-72 (1989).

Secretion of plasminogen activator in response to follicle-stimulating hormone in culture medium of human testicular cells from biopsy specimens
Y. Nishimune, K. Sawada, Y. Tajima, D. Watanabe, M. Maekawa, K. Sakamaki, A. Okuyama, M. Nakamura, M. Namiki and K. Matsumoto
J. Androl., 10, 283-8 (1989).

An attempt to evaluate human sperm fertilizing ability with a monoclonal antibody
M. Okabe, S. Matzno, M. Nagira, X. Ying, H. Umeki, M. Sekine and T. Mimura
Jap Soc Basic Reprod Immunol, 4, 26-29 (1989).

Glucosamine enhanced sperm-egg binding but inhibited sperm-egg fusion in mouse
M. Okabe, M. Yagasaki, S. Matzno, M. nagira, Y. Kohama and T. Mimura
Experientia, 45, 193-4 (1989).

Plasminogen activator activity of testicular cells of subfertile men and FSH in vitro
A. Okuyama, N. Nonomura, E. Koh, N. Kondoh, M. Nakamura, M. Namiki, H. Kiyohara, H. Fujioka, S. Mizutani and Y. Nishimune
Arch. Androl., 23, 235-42 (1989).

Plasminogen activator activity of testicular cells of subfertile men and FSH in vitro.
A. Okuyama, N. Nonomura, E. Koh, N. Kondoh, M. Nakamura, M. Namiki, H. Kiyohara, H. Fujioka, S. Mizutani, Y. Nishimune and e. al.
Arch Androl., 23, 235-42. (1989).

Induction of testicular DNA synthesis in vitro by hCG and hMG treatments in men with hypogonadotropic hypogonadism
A. Okuyama, N. Nonomura, E. Koh, N. Kondoh, M. Nakamura, M. Namiki, H. Kiyohara, Y. Nishimune, K. Matsumoto and M. Matsuda
Arch. Androl., 23, 39-43 (1989).

Induction of testicular DNA synthesis in vitro by hCG and hMG treatments in men with hypogonadotropic hypogonadism.
A. Okuyama, N. Nonomura, E. Koh, N. Kondoh, M. Nakamura, M. Namiki, H. Kiyohara, Y. Nishimune, K. Matsumoto, M. Matsuda and e. al.
Arch Androl., 23, 39-43 (1989).

In vitro responsiveness of human testicular DNA synthesis to gonadotropins.
A. Okuyama, N. Nonomura, E. Koh, N. Kondoh, M. Nakamura, M. Namiki, H. Kiyohara, Y. Nishimune, K. Matsumoto and T. Sonoda
Arch Androl., 22, 161-5 (1989).

In vitro responsiveness of human testicular DNA synthesis to gonadotropins
A. Okuyama, N. Nonomura, E. Koh, N. Kondoh, M. Nakamura, M. Namiki, H. Kiyohara, Y. Nishimune, K. Matsumoto and T. Sonoda
Arch. Androl., 22, 161-5 (1989).

Effectiveness of hMG-hCG treatment for DNA/RNA syntheses in subfertile human testis in vitro.
A. Okuyama, N. Nonomura, M. Nakamura, M. Namiki, E. Koh, N. Kondoh, H. Kiyohara, Y. Nishimune, K. Matsumoto and T. Sonoda
Arch Androl., 22, 167-72 (1989).

Effectiveness of hMG-hCG treatment for DNA/RNA syntheses in subfertile human testis in vitro
A. Okuyama, N. Nonomura, M. Nakamura, M. Namiki, E. Koh, N. Kondoh, H. Kiyohara, Y. Nishimune, K. Matsumoto and T. Sonoda
Arch. Androl., 22, 167-72 (1989).

Identification of peanut agglutinin receptors on mouse testicular germ cells
K. Sakamaki, K. Sawada, U. Koshimizu and Y. Nishimune
Biol. Reprod., 41, 1097-102 (1989).

Comparative platelet anti-aggregant activity of D-cysteinolic acid analogues
M. Satake, Y. Chiba, Y. Kohama, K. Yamamoto, M. Okabe, T. Mimura, T. Imanishi and C. Iwata
Experientia, 45, 1110-1112 (1989).
　

Male sterility of transgenic mice carrying exogenous mouse interferon-beta gene under the control of the metallothionein enhancer-promoter
Y. Iwakura, M. Asano, Y. Nishimune and Y. Kawade
EMBO. J., 7, 3757-62 (1988).

Effect of N-3-(4-hydroxyphenyl)propionyl Pro-Pro-Gly-Ala-Gly on calcium-induced arrhythmias
Y. Kohama, S. Kuwahara, K. Yamamoto, M. Okabe, T. Mimura, C. Fukaya, M. Watanabe and K. Yokoyama
Chem Pharm Bull Tokyo, 36, 4597-9 (1988).

Isolation of angiotensin-converting enzyme inhibitor from tuna muscle
Y. Kohama, S. Matsumoto, H. Oka, T. Teramoto, M. Okabe and T. Mimura
Biochem Biophys Res Commun, 155, 332-7 (1988).

Suppression of gastric ulcer induced by stress and HCL-ethanol by intravenously administered metallothionein-II
T. Mimura, K. Tsujikawa, N. Yasuda, H. Nakajima, M. Haruyama, T. Ohmura and M. Okabe
Biochem Biophys Res Commun, 151, 725-9 (1988).

Optimal temperature for synthesis of DNA, RNA, and protein by human testis in vitro
M. Nakamura, M. Namiki, A. Okuyama, E. Koh, N. Kondoh, M. Takeyama, H. Fujioka, Y. Nishimune, K. Matsumoto and M. Matsuda
Arch. Androl., 20, 41-4 (1988).

Studies of Sl/Sld in equilibrium with +/+ mouse aggregation chimaeras. II. Effect of the steel locus on spermatogenesis.
H. Nakayama, H. Kuroda, H. Onoue, J. Fujita, Y. Nishimune, K. Matsumoto, T. Nagano, F. Suzuki and Y. Kitamura
Development., 102, 117-26 (1988).

Studies of Sl/Sld <-> +/+ mouse aggregation chimaeras. II. Effect of the steel locus on spermatogenesis
H. Nakayama, H. Kuroda, H. Onoue, J. Fujita, Y. Nishimune, K. Matsumoto, T. Nagano, F. Suzuki and Y. Kitamura
Development, 102, 117-26 (1988).

An anti-mouse sperm monoclonal antibody (OBF13) and its inhibitory activity on fertilization
M. Okabe, T. Adachi, H. Oda, M. Yagasaki, Y. Kohama and T. Mimura
Jpn J Fertil Steril, 33, 473-478 (1988).

Flow cytometry of mouse sperm acrosome reaction using monoclonal anti-sperm antibody
M. Okabe, S. Matzno, M. Nagira, X. Ying, H. Morita, T. Mimura, Y. Kawai, T. Hama and T. Mayumi
Jap Soc Basic Reprod Immunol, 3, 46-50 (1988).

Effect of a monoclonal anti-mouse sperm antibody (OBF13) on the interaction of mouse sperm with zona-free mouse and hamster eggs
M. Okabe, M. Yagasaki, H. Oda, S. Matzno, Y. Kohama and T. Mimura
J Reprod Immunol, 13, 211-9 (1988).
　

Inhibitory effect of 2-(E-2-alkenoylamino)ethyl alkyl sulfides on gastric ulceration in rats. I. Effect of 2-(E-2-alkenoylamino)ethyl carbamoylmethyl sulfides on gastric secretion and various ulceration models in rats
M. Iwai, I. Kohda, C. Fukaya, Y. Naito, K. Yokoyama, H. Nakajima, K. Tsujikawa, M. Okabe and T. Mimura
Chem Pharm Bull Tokyo, 35, 4616-25 (1987).

Studies on pharmacological activation of human serum immunoglobulin G (IgG) by chemical modification and active subfragments. VII. Effect of carboxamidemethylated Fc (CM-Fc) fragment from human serum IgG on lymphocytes and macrophages
T. Mimura, S. Itoh, K. Tsujikawa, H. Nakajima, Y. Kohama, M. Okabe, M. Iwai, T. Ohmura and K. Yokoyama
Chem Pharm Bull Tokyo, 35, 4940-5 (1987).

Studies on pharmacological activation of human serum immunoglobulin G (IgG) by chemical modification and active subfragments. VI. Anti-allergic activity of carboxamidemethylated Fc (CM-Fc) fragment from human serum IgG
T. Mimura, S. Itoh, K. Tsujikawa, H. Nakajima, Y. Kohama, M. Okabe, M. Iwai, T. Ohmura and K. Yokoyama
Chem Pharm Bull Tokyo, 35, 4935-9 (1987).

Studies on biological activities of melanin from marine animals. V. Anti-inflammatory activity of low-molecular-weight melanoprotein from squid (Fr. SM II)
T. Mimura, S. Itoh, K. Tsujikawa, H. Nakajima, M. Satake, Y. Kohama and M. Okabe
Chem Pharm Bull Tokyo, 35, 1144-50 (1987).

Inhibitory effect of bis(2-(E-2-octenoylamino)ethyl) disulfide and 2(E-octenoylamino)ethyl carbamoylmethyl sulfide on various inflammation models
T. Mimura, H. Nakajima, Y. Kohama, M. Okabe, K. Tsujikawa, S. Itoh, T. Ohmura, M. Iwai and K. Yokoyama
Chem Pharm Bull, 35, 4585-91 (1987).

Temperature sensitivity of human spermatogonia and spermatocytes in vitro.
M. Nakamura, M. Namiki, A. Okuyama, T. Matsui, Y. Doi, M. Takeyama, H. Fujioka, Y. Nishimune, K. Matsumoto and T. Sonoda
Arch Androl., 19, 127-32 (1987).

Influence of temperature on the function of Sertoli and Leydig cells of human testes.
M. Namiki, M. Nakamura, A. Okuyama, T. Sonoda, Y. Nishimune, D. Takatsuka and K. Matsumoto
Fertil Steril., 47, 475-80 (1987).

Effects of a gonadotropin-releasing hormone agonist analog (ICI 118630) on endocrine functions of human testis in vivo and in vitro.
M. Namiki, N. Nonomura, M. Nakamura, A. Okuyama, T. Sonoda, Y. Nishimune and K. Matsumoto
Fertil Steril., 48, 1012-7 (1987).

Properties of recombinant hepatitis B vaccine
T. Ohmura, A. Ohmizu, A. Sumi, W. Ohtani, Y. Uemura, H. Arimura, M. Nishida, Y. Kohama, M. Okabe, T. Mimura and et al.
Biochem Biophys Res Commun, 149, 1172-8 (1987).

Capacitation-related changes in antigen distribution on mouse sperm heads and its relation to fertilization rate in vitro
M. Okabe, T. Adachi, K. Takada, H. Oda, M. Yagasaki, Y. Kohama and T. Mimura
J Reprod Immunol, 11, 91-100 (1987).

Studies on interaction of mouse sperm to zona-free mouse and hamster eggs
M. Okabe, M. Yagasaki, T. Adachi, H. Oda and T. Mimura
Jap Soc Basic Reprod Immunol, 2, 68-70 (1987).

Identification of the specific proteins associated with differentiation of spermatogonia in mice by two-dimensional gel electrophoresis.
K. Sakamaki, K. Sawada and Y. Nishimune
Biol Reprod., 37, 989-94 (1987).

精子の成熟と受精能獲得
岡部　勝
遺伝, 41, 14-19 (1987).
　

Dibutyryl adenosine cyclic monophosphate regulates differentiation of type A spermatogonia with vitamin A in adult mouse cryptorchid testis in vitro.
T. Haneji, S. Koide, Y. Nishimune and Y. Oota
Endocrinology., 119, 2490-6 (1986).

Potent platelet antiaggregant action of an antiarrhythmic peptide (AAP)
Y. Kohama, K. Iwabuchi, M. Okabe and T. Mimura
J Pharmacobiodyn, 9, 182-8 (1986).

Response of immunoreactive antiarrhythmic peptide (IR-AAP) level associated with experimental arrhythmia in rats
Y. Kohama, K. Iwabuchi, T. Shibahara, M. Okabe and T. Mimura
J Pharmacobiodyn, 9, 806-10 (1986).

Purification and characterization of a new peptide-mannan, SP-I, as a gastric secretion-inhibitory principle from autolysate of brewer's yeast
T. Mimura, Y. Makino, H. Nakajima, M. Okabe, Y. Kohama, T. Kato and M. Takeuchi
Chem Pharm Bull Tokyo, 34, 3312-9 (1986).

Fatty acids and sterols of the tunicate, Salpa thompsoni, from the Antarctic Ocean: chemical composition and hemolytic activity
T. Mimura, M. Okabe, M. Satake, T. Nakanishi, A. Inada, Y. Fujimoto, F. Hata, Y. Matsumura and N. Ikekawa
Chem Pharm Bull Tokyo, 34, 4562-8 (1986).

Studies on pharmacological activation of human serum IgG by chemical modification and active subfragments. V. Mechanism of anti-inflammatory action of carboxamide-methylated L-chain (Fr. I-L) and H-chain (Fr. I-H) from human serum IgG
T. Mimura, K. Tsujikawa, H. Nakajima, S. Itoh, M. Okabe, I. Kohda and K. Yokoyama
J Pharmacobiodyn, 9, 799-805 (1986).

Studies on pharmacological activation of human serum immunoglobulin G by chemical modification and active subfragments. IV. Induction of anti-inflammatory activity by chemical cleavage of interchain disulfide bonds in human immunoglobulin G and pharmacological activity of alkylated subfragments
T. Mimura, K. Tsujikawa, H. Nakajima, M. Okabe, Y. Kohama, M. Iwai and K. Yokoyama
J Pharmacobiodyn, 9, 46-54 (1986).

Reduction of human and rat testicular follicle stimulating hormone receptors by human menopausal gonadotrophin in vivo and in vitro.
M. Namiki, M. Nakamura, A. Okuyama, T. Sonoda, H. Itatani, H. Sugao, T. Sakurai, Y. Nishimune and K. Matsumoto
Clin Endocrinol (Oxf), 26, 675-84. (1986).

Effect of duration of cryptorchidism on ability of mouse germ cells to regenerate and differentiate.
Y. Nishimune, M. Maekawa, K. Sakamaki and T. Haneji
Arch Androl., 16, 89-96 (1986).

Testicular germ cell differentiation.
Y. Nishimune, K. Sakamaki, K. Sawada, M. Maekawa and T. Haneji
Tokai J Exp Clin Med., 11, 391-4 (1986).

Effect of glucose and phloretin-2'-beta-D-glucose (phloridzin) on in vitro fertilization of mouse ova
M. Okabe, T. Adachi, Y. Kohama and T. Mimura
Experientia, 42, 398-9 (1986).

Inconsistent reactivity of an anti-sperm monoclonal antibody and its relationship to sperm capacitation
M. Okabe, K. Takada, T. Adachi, Y. Kohama and T. Mimura
J Reprod Immunol, 9, 67-70 (1986).

Studies on sperm capacitation using monoclonal anti-body--disappearance of an antigen from the anterior part of mouse sperm head
M. Okabe, K. Takada, T. Adachi, Y. Kohama, T. Mimura and S. Aonuma
J Pharmacobiodyn, 9, 55-60 (1986).

モノクローン抗体による精子の受精能の測定
三村　務 and 岡部 勝
生産と技術, 38, 41-45 (1986).
　

Determination of immunoreactive antiarrhythmic peptide (AAP) in rats
Y. Kohama, Y. Kawahara, M. Okabe, T. Mimura and S. Aonuma
J Pharmacobiodyn, 8, 1024-31 (1985).

Separation of germ cells from somatic cells in mouse testis by affinity for a lectin, peanut agglutinin.
M. Maekawa and Y. Nishimune
Biol Reprod., 32, 419-25 (1985).

Effects of steel mutation on spermatogenesis stimulated by fetuin.
Y. Nishimune, T. Haneji, M. Maekawa, K. Sakamaki and Y. Kitamura
Arch Androl., 15, 117-21 (1985).

南極産オキアミから胃液分泌抑制活性を有する核酸分画の分離
三村　務, 前田和宏, 横田睦美, 岡部　勝, 佐竹幹雄 and 藤田孝夫
薬学雑誌, 105, 597-600 (1985).

Vitamin A and follicle-stimulating hormone synergistically induce differentiation of type A spermatogonia in adult mouse cryptorchid testes in vitro.
T. Haneji, M. Maekawa and Y. Nishimune
Endocrinology., 114, 801-5 (1984).

Production, purification and characterization of the plasminogen activator in teratocarcinoma stem cells induced with sodium butyrate.
N. Ichikawa, T. Miyashita, Y. Nishimune and A. Matsushiro
Biken J., 27, 143-51 (1984).

In vitro demonstration of deleterious effect of steel mutation on spermatogenesis in mice.
Y. Nishimune, T. Haneji, M. Maekawa and Y. Kitamura
J Cell Physiol., 118, 19-21 (1984).

Retinoids induce differentiation of type A spermatogonia in vitro: organ culture of mouse cryptorchid testes.
T. Haneji, M. Maekawa and Y. Nishimune
J Nutr., 113, 1119-23 (1983).

In vitro differentiation of Type A spermatogonia from mouse cryptorchid testes in serum-free media.
T. Haneji, M. Maekawa and Y. Nishimune
Biol Reprod., 28, 1217-23 (1983).

Mode of cell surface marker changes during retinoic acid-induced differentiation in pluripotent embryonal carcinoma cells.
A. Kume, Y. Ogiso, Y. Nishimune and A. Matsushiro
Exp Cell Res., 46, 385-90 (1983).

Molecular features and immunological properties of lactate dehydrogenase C4 isozymes from mouse and rat testes
S. S.-L. Li, R. J. Feldman, M. Okabe and Y. C.-E. Pan
J Biol Chem, 258, 7017-7028 (1983).

Amino acid sequence studies on lactate dehydrogenase C4 isozymes from mouse and rat testes
Y. C.-E. Pan, F. S. Sharief, M. Okabe, S. Huang and S. S.-L. Li
J Biol Chem, 258, 7005-7016 (1983).

Capacitation inducing activity of serum albumin in fertilization of mouse ova in vitro
S. Aonuma, M. Okabe, Y. Kishi, M. Kawaguchi and H. Yamada
J Pharmacobiodyn, 5, 980-7 (1982).

Etinoic acid (vitamin A acid) induces spermatogenesis in adult mouse cryptorchid testes in vitro.
T. Haneji, M. Maekawa and Y. Nishimune
Biochem Biophys Res Commun., 108, 1320-4 (1982).

Hormones and the differentiation of type A spermatogonia in mouse cryptorchid testes incubated in vitro.
T. Haneji and Y. Nishimune
J Endocrinol., 94, 43-50 (1982).

Effects of beta-mercaptoethanol-containing medium and feeder cells on the differentiation of embryonal carcinoma cells.
Y. Ogiso, A. Kume, Y. Nishimune and A. Matsushiro
Differentiation., 22, 218-21 (1982).

Reversible and irreversible stages in the transition of cell surface marker during the differentiation of pluripotent teratocarcinoma cell induced with
retinoic acid.
Y. Ogiso, A. Kume, Y. Nishimune and A. Matsushiro
Exp Cell Res., 137, 365-72 (1982).

Identification of lactate dehydrogenase-X translated in vitro from mouse testicular poly A-containing mRNA
M. Okabe, K. Akai and S. S.-L. Li
Int J Biochem, 14, 371-375 (1982).

Mexiletine hydrochloride (Ko 1173)の突然変異誘起性試験について
青沼　繁, 岡部　勝, 公平　宏 and 大岩陽子
基礎と臨床, 16, 81-85 (1982).

Zinc effects on mouse spermatozoa and in-vitro fertilization
S. Aonuma, M. Okabe, M. Kawaguchi and Y. Kishi
J Reprod Fertil, 63, 463-6 (1981).

Testicular DNA synthesis in vivo: comparison between unilaterally cryptorchid testis and contralateral intact testis in mouse.
Y. Nishimune and T. Haneji
Arch Androl., 6, 61-5. (1981).

Testicular DNA synthesis in vivo: changes in DNA synthetic activity following artificial cryptorchidism and its surgical reversal.
Y. Nishimune, T. Haneji and S. Aizawa
Testicular DNA synthesis in vivo: changes in DNA synthetic activity following artificial cryptorchidism and its surgical reversal., 35, 359-62 (1981).

Differential effects of cyclic AMP on DNA synthesis by germ cells and non-germ cells in mouse testicular culture.
Y. Nishimune, T. Haneji and S. Aizawa
J Endocrinol., 89, 257-62 (1981).

Fenoteral Hydrobromide (Th1165a)の突然変異誘起性試験について
青沼　繁, 岡部　勝, 公平　宏 and 大谷正洋
基礎と臨床, 15, 221-224 (1981).

Bunitrolol Hydrochloride(Ko1366)の突然変異誘起性試験について
青沼　繁, 岡部　勝, 公平　宏 and 大谷正洋
基礎と臨床, 16, 81-85 (1981).

Studies on sperm capacitation. IX. Movement characteristics of spermatozoa in relation to capacitation
S. Aonuma, M. Okabe, M. Kawaguchi and Y. Kishi
Chem Pharm Bull Tokyo, 28, 1497-502 (1980).

The effects of steel mutation on testicular germ cell differentiation.
Y. Nishimune, T. Haneji and Y. Kitamura
J Cell Physiol., 105, 137-41 (1980).

Pirenzepine Dihydrochloride (LS519)の突然変異誘起性試験について
青沼　繁, 岡部　勝, 公平　宏 and 大谷正洋
基礎と臨床, 14, 3394-3398 (1980).

In-vitro differentiation of type A spermatogonia in mouse cryptorchid testis.
S. Aizawa and Y. Nishimune
J Reprod Fertil., 56, 99-104. (1979).

Local development of mast cells from bone marrow-derived precursors in the skin of mice.
K. Hatanaka, Y. Kitamura and Y. Nishimune
Blood., 53, 142-7 (1979).

The effect of zinc ions on fertilization of mouse ova in vitro
S. Aonuma, M. Okabe and M. Kawaguchi
J Reprod Fertil, 53, 179-83 (1978).

The change of solubility properties of zona pellucida to proteases related to fertilizability of mouse ova in vitro
S. Aonuma, M. Okabe, Y. Kawai and M. Kawaguchi
Chem Pharm Bull Tokyo, 26, 405-10 (1978).

Testicular germ cell differentiation in vivo.
Y. Nishimune, S. Aizawa and T. Komastu
Fertil Steril, 29, 92-102 (1978).

Studies on sperm capacitation. V. Characterization of decapacitation factor from guinea-pig spermatozoa
S. Aonuma, M. Okabe, K. Suzuki, K. Matsumoto and Y. Kawai
Chem Pharm Bull Tokyo, 24, 907-11 (1976).

精子の受精能獲得に関する生理学的研究
青沼　繁, 岡部　勝 and 川口　誠
薬学雑誌, 96, 1307-1312 (1976).

Effect of uterine environment and uterine extract on guinea pig sperm metabolism
S. Aonuma, T. Mayumi, T. Noguchi, K. Suzuki and M. Okabe
Chem Pharm Bull Tokyo, 22, 1095-101 (1974).

Studies on sperm capacitation. I. The relationship between a guinea-pig sperm-coating antigen and a sperm capacitation phenomenon
S. Aonuma, T. Mayumi, K. Suzuki, T. Noguchi, M. Iwai and M. Okabe
J Reprod Fertil, 35, 425-32 (1973).

Prophage excision: specific gene amplification of excision-impaired lysogen after induction.
Y. Nishimune
Virology, 53, 236-46 (1973).

精子の受精能獲得に関する生理化学的研究(III）ウサギ及びモルモット精子のin vitro capacitationの誘発
青沼　繁, 真弓忠範, 鈴木宏治 and 岡部　勝
日本内分泌学雑誌, 49, 1161-1166 (1973).

精子の受精能獲得に関する生理化学的研究(第二報）精子のmaturationに伴う呼吸、嫌気的解糖、運動性及びacrosome reactionに対する変動
青沼　繁, 真弓忠範, 鈴木宏治, 岡部　勝, 岩井正和 and 川野博子
日本内分泌学雑誌, 49, 799-804 (1973).

Temperature-sensitivity of mouse testicular DNA synthesis in vitro.
Y. Nishimune and T. Komatsu
Exp Cell Res., 75, 514 -7 (1972).

Prophage excision: on the status of host chromosome after induction.
Y. Nishimune
Virology, 41, 541-8 (1970).

Suppressor-sensitive mutants of coliphage phi-80.
K. Sato, Y. Nishimune, M. Sato, R. Numich and A. Matsushiro
Virology, 34, 637-49 (1968).