Department of Immunochemistry

Staff:

Professor(SUP)

Hisashi Arase, M.D., Ph.D.

Associate Professor(SUP)

Tadahiro Suenaga, M.D., Ph.D.

Assistant Professor(SUP)

Masako Kohyama, Ph.D.

Specially Appointed Researcher

Wataru Nakai, Ph.D.

Kazuki Kishida, Ph.D

Graduate Student

Hideki Yorifuji, M.D.

Yushi Matsumoto, M.D.

Yuuta Shimizu

Tatsuya Shishido

Tatsuhiko Ozono, M.D.

Akihito Sakoguchi, M.D.

Yuriko Muramatsu

Undergraduate Student

Siripongvutikorn Yanakawee

Subjects:

1. Molecular mechanisms of autoimmune disease.
2. Role of paired receptors in host-pathogen interaction.
3. Mechanism of virus entry into cells.

Papers published in 2017

1. Structural and thermodynamic analyses reveal critical features of glycopeptide recognition by the human PILRα immune cell receptor.

   Atsushi Furukawa, Kosuke Kakita, Tomoki Yamada, Mikihiro Ishizuka, Jiro Sakamoto, Nanao Hatori, Naoyoshi Maeda, Fumina Ohsaka, Takashi Saitoh, Takao Nomura, Kimiko Kuroki, Hisanori Nambu, Hisashi Arase, Shigeki Matsunaga, Masahiro Anada, Toyoyuki Ose, Shunichi Hashimoto and Katsumi Maenaka

   J Biol Chem, 292 (51), 21128-21136, 2017.
2. Immune evasion of Plasmodium falciparum by RIFIN via inhibitory receptors.

   Fumiji Saito, Kouyuki Hirayasu, Takeshi Satoh, Christian W Wang, John Lusingu, Takao Arimori, Kyoko Shida, Nirianne Marie Q Palacpac, Sawako Itagaki, Shiroh Iwanaga, Eizo Takashima, Takafumi Tsuboi, Masako Kohyama, Tadahiro Suenaga, Marco Colonna, Junichi Takagi, Thomas Lavstsen, Toshihiro Horii and Hisashi Arase

   Nature, 552 (7683), 101-105, 2017.
3. The Fc Domain of Immunoglobulin Is Sufficient to Bridge NK Cells with Virally Infected Cells.

   Hong-Sheng Dai, Nathaniel Griffin, Chelsea Bolyard, Hsiaoyin Charlene Mao, Jianying Zhang, Timothy P Cripe, Tadahiro Suenaga, Hisashi Arase, Ichiro Nakano, E A Chiocca, Balveen Kaur, Jianhua Yu and Michael A Caligiuri

   Immunity, 47 (1), 159-170.e10, 2017.
4. Myeloperoxidase/HLA class II complexes recognized by autoantibodies in microscopic polyangiitis.

   Ryosuke Hiwa, Koichiro Ohmura, Noriko Arase, Hui Jin, Kouyuki Hirayasu, Masako Kohyama, Tadahiro Suenaga, Fumiji Saito, Chikashi Terao, Tatsuya Atsumi, Hirotsugu Iwatani, Tsuneyo Mimori and Hisashi Arase

   Arthritis Rheumatol, 69 (10), 2069-2080, 2017.
5. Novel autoantibody against the β2-glycoprotein I/HLA-DR complex in patients with refractory cutaneous ulcers.

   N Arase, K Tanimura, H Jin, T Yamaoka, M Kishibe, M Nishioka, E Kiyohara, M Tani, S Matsuoka, K Ohmura, K Takasugi, T Yamamoto, H Murota, H Arase and I Katayama

   Br J Dermatol, 178 (1), 272-275, 2017.

Link

Department of Immunochemistry

Research Institute for Microbial Diseases, Osaka University