Laboratory for Clinical Research on Infectious Diseases

Staff:

Specially Appointed Associate Professor

Wataru Kamitani, D.V.M., Ph.D

Specially Appointed Researcher

Yutaka Terada, D.V.M., Ph.D.

Graduate Student

Kengo Kawachi

Tsubasa Yamada

Subjects:

1. Analysis of SARS coronavirus-Host protein interactions
2. Studies on MERS coronavirus

Paper published in 2017

1. Broad-spectrum antiviral agents: secreted phospholipase A2 targets viral envelope lipid bilayers derived from the endoplasmic reticulum membrane.

   Ming Chen, Chie Aoki-Utsubo, Masanori Kameoka, Lin Deng, Yutaka Terada, Wataru Kamitani, Kei Sato, Yoshio Koyanagi, Makoto Hijikata, Keiko Shindo, Takeshi Noda, Michinori Kohara and Hak Hotta

   Sci Rep, 7 (1), 15931, 2017.
2. Construction of a high-yield dengue virus by replacing nonstructural proteins 3-4B without increasing virulence.

   Supranee Phanthanawiboon, Sabar Pambudi, Magot Diata Omokoko, Keiko Hanabara, Atchareeya A-Nuegoonpipat, Wataru Kamitani, Kazuyoshi Ikuta and Takeshi Kurosu

   Biochem Biophys Res Commun, 495 (1), 1221-1226, 2018.
3. Two-amino acids change in the nsp4 of SARS coronavirus abolishes viral replication.

   Yusuke Sakai, Kengo Kawachi, Yutaka Terada, Hiroko Omori, Yoshiharu Matsuura and Wataru Kamitani

   Virology, 510, 165-174, 2017.
4. MERS coronavirus nsp1 participates in an efficient propagation through a specific interaction with viral RNA.

   Yutaka Terada, Kengo Kawachi, Yoshiharu Matsuura and Wataru Kamitani

   Virology, 511, 95-105, 2017.

Link

Laboratory for Clinical Research on Infectious Diseases

Research Institute for Microbial Diseases, Osaka University