BIKEN Endowed Department of Dengue Vaccine Development

Staff:

Endowed Chair Professor

Eiji Konishi, Ph.D.

Endowed Assistant Professor

Atsushi Yamanaka, Ph.D.

Graduate Student (student of Mahidol University)

Hisham Ahmed Imad

Paweena Manmee

Chayada Khamsawad

Subjects:

1. Development of dengue vaccine candidates
2. Analysis of dengue-induced antibodies

Paper published in 2016

1. Strategies to improve the immunogenicity of prM+E dengue virus type-2 DNA vaccine.

   Chutitorn Ketloy, Poonsook Keelapang, Eakachai Prompetchara, Amporn Suphatrakul, Chunya Puttikhunt, Watchara Kasinrerk, Eiji Konishi, Nopporn Sittisombut and Kiat Ruxrungtham

   Asian Pac J Allergy Immunol, 35 (1), 11-19, 2016.
2. Bivalent vaccine platform based on Japanese encephalitis virus (JEV) elicits neutralizing antibodies against JEV and hepatitis C virus.

   Ryohei Saga, Akira Fujimoto, Noriyuki Watanabe, Mami Matsuda, Makoto Hasegawa, Koichi Watashi, Hideki Aizaki, Noriko Nakamura, Shigeru Tajima, Tomohiko Takasaki, Eiji Konishi, Takanobu Kato, Michinori Kohara, Haruko Takeyama, Takaji Wakita and Ryosuke Suzuki

   Sci Rep, 6, 28688, 2016.
3. Unique Requirement for ESCRT Factors in Flavivirus Particle Formation on the Endoplasmic Reticulum.

   Keisuke Tabata, Masaru Arimoto, Masashi Arakawa, Atsuki Nara, Kazunobu Saito, Hiroko Omori, Arisa Arai, Tomohiro Ishikawa, Eiji Konishi, Ryosuke Suzuki, Yoshiharu Matsuura and Eiji Morita

   Cell Rep, 16 (9), 2339-2347, 2016.
4. Dengue virus infection-enhancing antibody activities against Indonesian strains in inhabitants of central Thailand.

   Atsushi Yamanaka, Duangjai Oddgun, Nantarat Chantawat, Tamaki Okabayashi, Pongrama Ramasoota, Siti Churrotin, Tomohiro Kotaki, Masanori Kameoka, Soegeng Soegijanto and Eiji Konishi

   Microbes Infect, 18 (4), 277-284, 2016.
5. Divergence of the dengue virus type 2 Cosmopolitan genotype associated with two predominant serotype shifts between 1 and 2 in Surabaya, Indonesia, 2008-2014.

   Tomohiro Kotaki, Atsushi Yamanaka, Kris Cahyo Mulyatno, Siti Churrotin, Teguh Hari Sucipto, Amaliah Labiqah, Nur Laila Fitriati Ahwanah, Soegeng Soegijanto, Masanori Kameoka and Eiji Konishi

   Infect Genet Evol, 37, 88-93, 2016.

Link

Research Institute for Microbial Diseases, Osaka University