Department of Viral Infections

Staff:

Professor

Tatsuo Shioda, Ph.D.

Associate Professor

Emi E. Nakayama, M.D., Ph.D.

Assistant Professor

Jun-ichi Sakuragi, Ph.D.

Specially Appointed Assistant Professor

Akatsuki Saito,V.M.D., Ph.D

Specially Appointed Researcher

Sayuri Sakuragi, Ph.D.

Eri Takeda, Ph.D.

Graduate Student

Tahmina Sultana

Priya Dhole,

Yasuha Arai

Special Auditor

Richard Atherton Luke

Undergraduate Student

Kyotaro Nohata

Subjects:

1. Analysis of host genetic factors affecting disease courses of human immunodeficiency virus (HIV) infection.
2. Studies on restriction factors of HIV infection.
3. Analysis of molecular mechanisms of HIV entry into target cells.
4. Analysis of molecular mechanisms of HIV virion formation.
5. Development of diagnose kit for dengue and Chikungunya viruses.
6. Development of anti-dengue virus reagents.

Papers published in 2015

1. Fibrocytes Differ from Macrophages but Can Be Infected with HIV-1.

   Michihiro Hashimoto, Hesham Nasser, Farzana Bhuyan, Nozomi Kuse, Yorifumi Satou, Shigeyoshi Harada, Kazuhisa Yoshimura, Jun-ichi Sakuragi, Kazuaki Monde, Yosuke Maeda, Sarah Welbourn, Klaus Strebel, Ekram W Abd El-Wahab, Mitsue Miyazaki, Shinichiro Hattori, Nopporn Chutiwitoonchai, Masateru Hiyoshi, Shinichi Oka, Masafumi Takiguchi and Shinya Suzu

   J Immunol, 195 (9), 4341-4350, 2015.
2. Impact of TRIM5α in vivo.

   Emi E Nakayama and Tatsuo Shioda

   AIDS, 29 (14), 1733-1743, 2015.
3. Genome-Wide Association Study of HIV-Related Lipoatrophy in Thai Patients: Association of a DLGAP1 Polymorphism with Fat Loss.

   Sumonmal Uttayamakul, Tiphaine Oudot-Mellakh, Emi E Nakayama, Pimrapat Tengtrakulcharoen, Julien Guergnon, Jean-Francois Delfraissy, Srisin Khusmith, Chariya Sangsajja, Sirirat Likanonsakul, Ioannis Theodorou and Tatsuo Shioda

   AIDS Res Hum Retroviruses, 31 (8), 792-796, 2015.
4. Properties of human immunodeficiency virus type 1 reverse transcriptase recombination upon infection.

   Sayuri Sakuragi, Tatsuo Shioda and Jun-ichi Sakuragi

   J Gen Virol, 96 (11), 3382-3388, 2015.
5. Fluorescent Image Analysis of HIV-1 and HIV-2 Uncoating Kinetics in the Presence of Old World Monkey TRIM5α.

   Eri Takeda, Ken Kono, Amy E Hulme, Thomas J Hope, Emi E Nakayama and Tatsuo Shioda

   PLoS One, 10 (3), e0121199, 2015.
6. The HIV-1 Gp120/CXCR4 Axis Promotes CCR7 Ligand-Dependent CD4 T Cell Migration: CCR7 Homo- and CCR7/CXCR4 Hetero-Oligomer Formation as a Possible Mechanism for Up-Regulation of Functional CCR7.

   Haruko Hayasaka, Daichi Kobayashi, Hiromi Yoshimura, Emi E Nakayama, Tatsuo Shioda and Masayuki Miyasaka

   PLoS One, 10 (2), e0117454, 2015.

Link

Department of Viral Infections

Research Institute for Microbial Diseases, Osaka University