Section of Viral Infections

RESEARCH COLLABORATION CENTER ON EMERGING AND RE-EMERGING INFECTIONS:

Staff:

Specially Appointed Professor

Naokazu Takeda, Ph.D.

Specially Appointed Associate Professor

Kazushi Motomura, M.D., Ph.D.

Atsushi Tanaka, D.V.M, Ph.D.

Postdoctoral Fellow

Nitchakarn Noranate, Ph.D.

Assistant Researcher

Uranan Tumkosit, M.Sc.

Michittra Boonchan, M.Sc.

Thongkoon Priengpom, M.Sc.

Subjects:

1. Epidemiological study on hepatitis E virus infection in Thai population.
2. Production of monoclonal antibodies against chikungunya virus proteins and its application.
3. Determination of cellular factors involved in chikungunya virus infection.
4. Construction of norovirus virus-like particle and development of ELISA system.
5. Epidemiological studies on water-borne viral infections in Thailand.
6. HIV-1 drug resistance test by using ultra deep sequencing.

Papers published in 2015

1. Transmission and Demographic Dynamics of Coxsackievirus B1.

   Pei-Yu Chu, Yu-Chang Tyan, Yao-Shen Chen, Hsiu-Lin Chen, Po-Liang Lu, Yu-Hsien Chen, Bao-Chen Chen, Tsi-Shu Huang, Chu-Feng Wang, Hui-Ju Su, Yong-Ying Shi, Bintou Sanno-Duanda, Kuei-Hsiang Lin and Kazushi Motomura

   PLoS One, 10 (6), e0129272, 2015.
2. Monkeys and Rats Are Not Susceptible to Ferret Hepatitis E Virus Infection.

   Tian-Cheng Li, Sayaka Yoshizaki, Yasushi Ami, Yuriko Suzaki, Tingting Yang, Naokazu Takeda and Wakita Takaji

   Intervirology, 58 (3), 139-142, 2015.
3. Long-term viral shedding and viral genome mutation in norovirus infection.

   Tatsuya Miyoshi, Kiyoko Uchino, Hisayoshi Yoshida, Kazushi Motomura, Naokazu Takeda, Yoshiharu Matsuura and Tomoyuki Tanaka

   J Med Virol, 87 (11), 1872-1880, 2015.
4. Generation of hepatitis E virus-like particles of two new genotypes G5 and G6 and comparison of antigenic properties with those of known genotypes.

   Tian-Cheng Li, Michiyo Kataoka, Kazuaki Takahashi, Sayaka Yoshizaki, Takanobu Kato, Koji Ishii, Naokazu Takeda, Shunji Mishiro and Takaji Wakita

   Vet Microbiol, 178 (1-2), 150-157, 2015.
5. Search for Low Molecular Weight Compounds that Inhibit Human Immunodeficiency Virus Type 1 Replication

   Chris Verathamjamras, Yu-Shi Tian, Norihito Kawashita, Kousuke Okamoto, Teruo Yasunaga, Kazuyoshi Ikuta, Kazushi Motomura, Naokazu Takeda, Tatsuya Takagi and Masanori Kameoka

   J Infect Dis Ther, 3 (3), 218, 2015.
6. Characterization of self-assembled virus-like particles of dromedary camel hepatitis e virus generated by recombinant baculoviruses.

   Xianfeng Zhou, Michiyo Kataoka, Zheng Liu, Naokazu Takeda, Takaji Wakita and Tian-Cheng Li

   Virus Res, 210, 8-17, 2015.
7. Characterization of self-assembled virus-like particles of merkel cell polyomavirus.

   Tian-Cheng Li, Kenji Iwasaki, Harutaka Katano, Michiyo Kataoka, Noriyo Nagata, Kazumi Kobayashi, Tetsuya Mizutani, Naokazu Takeda, Takaji Wakita and Tetsuro Suzuki

   PLoS One, 10 (2), e0115646, 2015.
8. Mapping Broadly Reactive Norovirus Genogroup I and II Monoclonal Antibodies.

   Sue E Crawford, Nadim Ajami, Tracy Dewese Parker, Noritoshi Kitamoto, Katsuro Natori, Naokazu Takeda, Tomoyuki Tanaka, Baijun Kou, Robert L Atmar and Mary K Estes

   Clin Vaccine Immunol, 22 (2), 168-177, 2015.
9. Dominant mutations in ORAI1 cause tubular aggregate myopathy with hypocalcemia via constitutive activation of store-operated Ca2+ channels.

   Yukari Endo, Satoru Noguchi, Yuji Hara, Yukiko K Hayashi, Kazushi Motomura, Satoko Miyatake, Nobuyuki Murakami, Satsuki Tanaka, Sumimasa Yamashita, Rika Kizu, Masahiro Bamba, Yu-Ichi Goto, Naomichi Matsumoto, Ikuya Nonaka and Ichizo Nishino

   Hum Mol Genet, 24 (3), 637-648, 2015.
10. Neutralization Activity of Patient Sera Collected during the 2008-2009 Chikungunya Outbreak in Thailand.

    Natsuko Kishishita, Mikiko Sasayama, Naokazu Takeda, Areerat Sa-Ngasang, Atchareeya Anuegoonpipat and Surapee Anantapreecha

    J Clin Microbiol, 53 (1), 184-190, 2015.
11. Ferret hepatitis e virus infection in Japan.

    Tian-Cheng Li, Kenzo Yonemitsu, Yutaka Terada, Naokazu Takeda, Wakita Takaji and Ken Maeda

    Jpn J Infect Dis, 68 (1), 60-62, 2015.

Link

Section of Viral Infections

Research Institute for Microbial Diseases, Osaka University

http://rcc-eri.biken.osaka-u.ac.jp/e/viral_infections.html