Department of Immunochemistry

Staff:

Professor

Hisashi Arase, M.D., Ph.D.

Associate Professor

Tadahiro Suenaga, M.D., Ph.D.

Masako Kohyama, Ph.D.

Specially Appointed Researcher

Noriko Arase, M.D., Ph.D.

Fumiji Saito, Ph.D.

Kazuki Kishida, Ph.D

JSPS Postdoctoral Fellowship for Foreign Researcher

Hui Jin, Ph.D.

Graduate Student

Hideki Yorifuji, M.D.

Yushi Matsumoto, M.D.

Yuuta Shimizu

Tatsuya Shishido

Subjects:

1. Molecular mechanisms of autoimmune disease.
2. Role of paired receptors in host-pathogen interaction.
3. Mechanism of virus entry into cells.

Papers published in 2015

1. Functional and genetic diversity of leukocyte immunoglobulin-like receptor and implication for disease associations.

   Kouyuki Hirayasu and Hisashi Arase

   J Hum Genet, 60 (11), 703-708, 2015.
2. Sialic Acids on Varicella-Zoster Virus Glycoprotein B Are Required for Cell-Cell Fusion.

   Tadahiro Suenaga, Maki Matsumoto, Fuminori Arisawa, Masako Kohyama, Kouyuki Hirayasu, Yasuko Mori and Hisashi Arase

   J Biol Chem, 290 (32), 19833-19843, 2015.
3. Endothelial CD99 signals through soluble adenylyl cyclase and PKA to regulate leukocyte transendothelial migration.

   Richard L Watson, Jochen Buck, Lonny R Levin, Ryan C Winger, Jing Wang, Hisashi Arase and William A Muller

   J Exp Med, 212 (7), 1021-1041, 2015.
4. Cellular misfolded proteins rescued from degradation by MHC class II molecules are possible targets for autoimmune diseases.

   Noriko Arase and Hisashi Arase

   J Biochem, 158 (5), 367-372, 2015.
5. β2-Glycoprotein I/HLA class II complexes are novel autoantigens in antiphospholipid syndrome.

   Kenji Tanimura, Hui Jin, Tadahiro Suenaga, Satoko Morikami, Noriko Arase, Kazuki Kishida, Kouyuki Hirayasu, Masako Kohyama, Yasuhiko Ebina, Shinsuke Yasuda, Tetsuya Horita, Kiyoshi Takasugi, Koichiro Ohmura, Ken Yamamoto, Ichiro Katayama, Takehiko Sasazuki, Lewis L Lanier, Tatsuya Atsumi, Hideto Yamada and Hisashi Arase

   Blood, 125 (18), 2835-2844, 2015.
6. Negative regulation of DSS-induced experimental colitis by PILRα.

   Kazuki Kishida, Masako Kohyama, Yosuke Kurashima, Yuta Kogure, Jing Wang, Kouyuki Hirayasu, Tadahiro Suenaga, Hiroshi Kiyono, Jun Kunisawa and Hisashi Arase

   Int Immunol, 27 (6), 307-314, 2015.

Link

Department of Immunochemistry

Research Institute for Microbial Diseases, Osaka University