Department of Genome Informatics

Staff:

Professor

Teruo Yasunaga, Ph.D.

Professor(SUP)

Tatsuya Takagi, Ph.D.

Associate Professor

Naohisa Goto, Ph.D.

Shota Nakamura, Ph.D.

Associate Professor(SUP)

Norihito Kawashita, Ph.D.

Subjects:

1. Bioinformatics and molecular evolution analysis of genes and genomes.
2. Analysis of protein 3-D structure information for drug discovery and design.
3. Genome sequencing of disease-causing organisms in collaboration with other laboratories.
4. Development of genome information analysis software, including Next-Generation Sequencing data management and analysis.

Published Papers in 2015

1. Oxidative rearrangement of cyclobutanone derived N,O-ketals leading to pyrrolidone derivatives.

   Kenichi Murai, Daisuke Endo, Norihito Kawashita, Tatsuya Takagi and Hiromichi Fujioka

   Chem Pharm Bull (Tokyo), 63 (4), 245-247, 2015.
2. Pharmacophore Modeling and Molecular Docking Studies of potential inhibitors to E6 PBM-PDZ from Human Papilloma Virus (HPV).

   Yu-Shi Tian, Norihito Kawashita, Yuki Arai, Kousuke Okamoto and Tatsuya Takagi

   Bioinformation, 11 (8), 401-406, 2015.
3. Genetic analysis of genes causing hypertension and stroke in spontaneously hypertensive rats: Gene expression profiles in the kidneys.

   Yuko Watanabe, Momoko Yoshida, Kyosuke Yamanishi, Hideyuki Yamamoto, Daisuke Okuzaki, Hiroshi Nojima, Teruo Yasunaga, Haruki Okamura, Hisato Matsunaga and Hiromichi Yamanishi

   Int J Mol Med, 36 (3), 712-724, 2015.
4. Characterization of H5N1 influenza virus variants with hemagglutinin mutations isolated from patients.

   Yohei Watanabe, Yasuha Arai, Tomo Daidoji, Norihito Kawashita, Madiha S Ibrahim, Emad El-Din M El-Gendy, Hiroaki Hiramatsu, Ritsuko Kubota-Koketsu, Tatsuya Takagi, Takeomi Murata, Kazuo Takahashi, Yoshinobu Okuno, Takaaki Nakaya, Yasuo Suzuki and Kazuyoshi Ikuta

   MBio, 6 (2), , 2015.

Link

Department of Genome Informatics

Research Institute for Microbial Diseases, Osaka University