Department of Bacterial Infections

Staff:

Professor

Tetsuya Iida, Ph.D.

Associate Professor

Toshio Kodama, Ph.D.

Assistant Professor

Shigeaki Matsuda, Ph.D.

Specially Appointed Researcher

Chonchanok Theethakaew, Ph.D.

Ryu Okada, Ph.D.

Graduate Student

Sarunporn Tandhavanant

Shinya Yonogi

Haruka Hayashi

Subjects:

1. Characterization of the mechanism(s) used by bacterial pathogens to infect host organisms by identifying infection-related changes in pathogen genome expression.
2. Analysis of the mechanism(s) that lead to the emergence of new infectious diseases.
3. Investigation of the life cycles of bacterial pathogens in their natural environments.
4. Development of new methods for the rapid identification of bacterial pathogens based on genome information

Papers published in 2015

1. Baseline Assessment of Mesophotic Reefs of the Vitória-Trindade Seamount Chain Based on Water Quality, Microbial Diversity, Benthic Cover and Fish Biomass Data.

   Pedro M Meirelles, Gilberto M Amado-Filho, Guilherme H Pereira-Filho, Hudson T Pinheiro, Rodrigo L de Moura, Jean-Christophe Joyeux, Eric F Mazzei, Alex C Bastos, Robert A Edwards, Elizabeth Dinsdale, Rodolfo Paranhos, Eidy O Santos, Tetsuya Iida, Kazuyoshi Gotoh, Shota Nakamura, Tomoo Sawabe, Carlos E Rezende, Luiz M R Gadelha, Ronaldo B Francini-Filho, Cristiane Thompson and Fabiano L Thompson

   PLoS One, 10 (6), e0130084, 2015.
2. Cloning, expression, purification, crystallization and X-ray crystallographic analysis of CofB, the minor pilin subunit of CFA/III from human enterotoxigenic Escherichia coli.

   Kazuki Kawahara, Hiroya Oki, Shunsuke Fukakusa, Takahiro Maruno, Yuji Kobayashi, Daisuke Motooka, Tooru Taniguchi, Takeshi Honda, Tetsuya Iida, Shota Nakamura and Tadayasu Ohkubo

   Acta Crystallogr F Struct Biol Commun, 71 (Pt 6), 663-667, 2015.
3. Metagenomic Analysis Reveals Dynamic Changes of Whole Gut Microbiota in the Acute Phase of Intensive Care Unit Patients.

   Masahiro Ojima, Daisuke Motooka, Kentaro Shimizu, Kazuyoshi Gotoh, Ayumi Shintani, Kazuhisa Yoshiya, Shota Nakamura, Hiroshi Ogura, Tetsuya Iida and Takeshi Shimazu

   Dig Dis Sci, , , 2015.
4. A repeat unit of Vibrio diarrheal T3S effector subverts cytoskeletal actin homeostasis via binding to interstrand region of actin filaments.

   Mitsuhiro Nishimura, Takashi Fujii, Hirotaka Hiyoshi, Fumiaki Makino, Hajime Inoue, Daisuke Motooka, Toshio Kodama, Tadayasu Ohkubo, Yuji Kobayashi, Shota Nakamura, Keiichi Namba and Tetsuya Iida

   Sci Rep, 5, 10870, 2015.
5. Regulation of Vibrio parahaemolyticus T3SS2 gene expression and function of T3SS2 effectors that modulate actin cytoskeleton.

   Toshio Kodama, Hirotaka Hiyoshi, Ryu Okada, Shigeaki Matsuda, Kazuyoshi Gotoh and Tetsuya Iida

   Cell Microbiol, 17 (2), 183-190, 2015.
6. Microbial community diversity and physical-chemical features of the Southwestern Atlantic Ocean.

   Nelson Alves Junior, Pedro Milet Meirelles, Eidy de Oliveira Santos, Bas Dutilh, Genivaldo G Z Silva, Rodolfo Paranhos, Anderson S Cabral, Carlos Rezende, Tetsuya Iida, Rodrigo L de Moura, Ricardo Henrique Kruger, Renato C Pereira, Rogério Valle, Tomoo Sawabe, Cristiane Thompson and Fabiano Thompson

   Arch Microbiol, 197 (2), 165-179, 2015.
7. Interaction between the Type III Effector VopO and GEF-H1 Activates the RhoA-ROCK Pathway.

   Hirotaka Hiyoshi, Ryu Okada, Shigeaki Matsuda, Kazuyoshi Gotoh, Yukihiro Akeda, Tetsuya Iida and Toshio Kodama

   PLoS Pathog, 11 (3), e1004694, 2015.
8. Emergence of infectious malignant thrombocytopenia in Japanese macaques (Macaca fuscata) by SRV-4 after transmission to a novel host.

   Munehiro Okamoto, Takayuki Miyazawa, Shigeru Morikawa, Fumiko Ono, Shota Nakamura, Eiji Sato, Tomoyuki Yoshida, Rokusuke Yoshikawa, Kouji Sakai, Tetsuya Mizutani, Noriyo Nagata, Jun-Ichiro Takano, Sachi Okabayashi, Masataka Hamano, Koji Fujimoto, Takaaki Nakaya, Tetsuya Iida, Toshihiro Horii, Takako Miyabe-Nishiwaki, Akino Watanabe, Akihisa Kaneko, Akatsuki Saito, Atsushi Matsui, Toshiyuki Hayakawa, Juri Suzuki, Hirofumi Akari, Tetsuro Matsuzawa and Hirohisa Hirai

   Sci Rep, 5, 8850, 2015.

Link

Department of Bacterial Infections

Research Institute for Microbial Diseases, Osaka University