Research Center for Infectious Disease Control

Staff:

Assitant Professor

Takeshi Kurosu, D.V.M., Ph.D.

Yohei Watanabe, D.V.M., Ph.D.

Collaborator

Ritsuko Koketsu, Ph.D.

Subjects:

1. Characterization of H5N1? influenza virus variants with mutations isolated inpatients
2. Characterization of human monoclonal antibodies that broadly cross-neutralize influenza A viruses
3. Establishment of new mouse model of dengue virus infection

Papers published in 2014

1. Isolation and propagation of Dengue virus in Vero and BHK-21 cells expressing human DC-SIGN stably.

   Supranee Phanthanawiboon, Atchareeya A-nuegoonpipat, Narawan Panngarm, Kriengsak Limkittikul, Kazuyoshi Ikuta, Surapee Anantapreecha and Takeshi Kurosu

   J Virol Methods, 209, 55-61, 2014.
2. A human monoclonal antibody derived from a vaccinated volunteer recognizes heterosubtypically a novel epitope on the hemagglutinin globular head of H1 and H9 influenza A viruses.

   Naphatsawan Boonsathorn, Sumolrat Panthong, Sarawut Koksunan, Malinee Chittaganpitch, Siripaporn Phuygun, Sunthareeya Waicharoen, Apichai Prachasupap, Tadahiro Sasaki, Ritsuko Kubota-Koketsu, Mayo Yasugi, Ken-Ichiro Ono, Yasuha Arai, Takeshi Kurosu, Pathom Sawanpanyalert, Kazuyoshi Ikuta and Yohei Watanabe

   Biochem Biophys Res Commun, 452 (3), 865-870, 2014.
3. A novel immunochromatographic system for easy-to-use detection of group 1 avian influenza viruses with acquired human-type receptor binding specificity.

   Yohei Watanabe, Tetsuo Ito, Madiha S Ibrahim, Yasuha Arai, Kozue Hotta, Hoang Vu Mai Phuong, Nguyen Le Khanh Hang, Le Quynh Mai, Kosuke Soda, Masaoki Yamaoka, Emmanuel Djoko Poetranto, Laksmi Wulandari, Hiroaki Hiramatsu, Tomo Daidoji, Ritsuko Kubota-Koketsu, Nongluk Sriwilaijaroen, Takaaki Nakaya, Yoshinobu Okuno, Tadanobu Takahashi, Takashi Suzuki, Toshihiro Ito, Hak Hotta, Tetsu Yamashiro, Tsukasa Hayashi, Kouichi Morita, Kazuyoshi Ikuta and Yasuo Suzuki

   Biosens Bioelectron, 65C, 211-219, 2014.
4. Sequence variation of dengue type 2 virus isolated from clinical cases in Thailand.

   Takeshi Kurosu, Panjaporn Chaichana, Supranee Phanthanawiboon, Chidchanok Khamlert, Akifumi Yamashita, Atchareeya A-nuegoonpipat, Kazuyoshi Ikuta and Surapee Anantapreecha

   Jpn J Infect Dis, 67 (2), 132-134, 2014.
5. Human monoclonal antibodies derived from a patient infected with 2009 pandemic influenza A virus broadly cross-neutralize group 1 influenza viruses.

   Yang Pan, Tadahiro Sasaki, Ritsuko Kubota-Koketsu, Yuji Inoue, Mayo Yasugi, Akifumi Yamashita, Ririn Ramadhany, Yasuha Arai, Anariwa Du, Naphatsawan Boonsathorn, Madiha S Ibrahim, Tomo Daidoji, Takaaki Nakaya, Ken-ichiro Ono, Yoshinobu Okuno, Kazuyoshi Ikuta and Yohei Watanabe

   Biochem Biophys Res Commun, 450 (1), 42-48, 2014.
6. Chikungunya virus was isolated in Thailand, 2010.

   Mikiko Sasayama, Surachet Benjathummarak, Norihito Kawashita, Prasert Rukmanee, Suntaree Sangmukdanun, Promsin Masrinoul, Pannamthip Pitaksajjakul, Orapim Puiprom, Pitak Wuthisen, Takeshi Kurosu, Panjaporn Chaichana, Pannamas Maneekan, Kazuyoshi Ikuta, Pongrama Ramasoota, Tamaki Okabayashi, Pratap Singhasivanon and Natthanej Luplertlop

   Virus Genes, 49 (3), 485-489, 2014.
7. Proteolysis of abnormal prion protein with a thermostable protease from Thermococcus kodakarensis KOD1.

   Yuichi Koga, Shun-ichi Tanaka, Akikazu Sakudo, Minoru Tobiume, Mutsuo Aranishi, Azumi Hirata, Kazufumi Takano, Kazuyoshi Ikuta and Shigenori Kanaya

   Appl Microbiol Biotechnol, 98 (5), 2113-2120, 2014.

Link

Lab HP

Department of Virology

Research Institute for Microbial Diseases, Osaka University