BIKEN Endowed Department of Dengue Vaccine Development

Staff:

Endowed Chair Professor

Eiji Konishi, Ph.D.

Endowed Assistant Professor

Atsushi Yamanaka, Ph.D.

Subjects:

1. Development of dengue vaccine candidates
2. Analysis of dengue-induced antibodies

Paper published in 2014

1. Continuous dengue type 1 virus genotype shifts followed by co-circulation, clade shifts and subsequent disappearance in Surabaya, Indonesia, 2008-2013.

   Tomohiro Kotaki, Atsushi Yamanaka, Kris Cahyo Mulyatno, Siti Churrotin, Amaliah Labiqah, Teguh Hari Sucipto, Soegeng Soegijanto, Masanori Kameoka and Eiji Konishi

   Infect Genet Evol, 28C, 48-54, 2014.
2. Dengue transmission model by means of viremic adult immuno-competent mouse.

   Lucky Ronald Runtuwene, Eiji Konishi, Atsushi Yamanaka, Yoshihiro Makino, Yutaka Suzuki, Tomohiko Takasaki, Ichiro Kurane, Takashi Kobayashi and Yuki Eshita

   Parasit Vectors, 7, 143, 2014.
3. Phylogenetic analysis of dengue virus type 3 strains primarily isolated in 2013 from Surabaya, Indonesia.

   Tomohiro Kotaki, Atsushi Yamanaka, Kris Cahyo Mulyatno, Amaliah Labiqah, Teguh Hari Sucipto, Siti Churrotin, Soegeng Soegijanto, Eiji Konishi and Masanori Kameoka

   Jpn J Infect Dis, 67 (3), 227-229, 2014.
4. Evaluation of chimeric DNA vaccines consisting of premembrane and envelope genes of Japanese encephalitis and dengue viruses as a strategy for reducing induction of dengue virus infection-enhancing antibody response.

   Fithriyah Sjatha, Miwa Kuwahara, T Mirawati Sudiro, Masanori Kameoka and Eiji Konishi

   Microbiol Immunol, 58 (2), 126-134, 2014.
5. Evaluation of single-round infectious, chimeric dengue type 1 virus as an antigen for dengue functional antibody assays.

   Atsushi Yamanaka, Ryosuke Suzuki and Eiji Konishi

   Vaccine, 32 (34), 4289-4295, 2014.
6. Production of single-round infectious chimeric flaviviruses with DNA-based Japanese encephalitis virus replicon.

   Ryosuke Suzuki, Tomohiro Ishikawa, Eiji Konishi, Mami Matsuda, Koichi Watashi, Hideki Aizaki, Tomohiko Takasaki and Takaji Wakita

   J Gen Virol, 95 (Pt 1), 60-65, 2014.
7. A review of successful flavivirus vaccines and the problems with those flaviviruses for which vaccines are not yet available.

   Tomohiro Ishikawa, Atsushi Yamanaka and Eiji Konishi

   Vaccine, 32 (12), 1326-1337, 2014.
8. Japanese encephalitis: epidemiology, prevention and current status of antiviral drug development

   Tomohiro Ishikawa and Eiji Konishi

   Expert Opinion on Orphan Drugs, 2 (9), 923-936, 2014.

Link

BIKEN Endowed Department of Dengue Vaccine Development

Research Institute for Microbial Diseases, Osaka University