Section of Viral Infections

RESEARCH COLLABORATION CENTER ON EMERGING AND RE-EMERGING INFECTIONS:

Staff:

Specially Appointed Professor

Naokazu Takeda, Ph.D.

Specially Appointed Associate Professor

Kazushi Motomura, M.D., Ph.D.

Specially Appointed Associate Professor

Atsushi Tanaka, D.V.M, Ph.D.

Subjects:

1. Epidemiological study on hepatitis E virus infection in Thai population.
2. Production of monoclonal antibodies against chikungunya virus proteins and its application.
3. Determination of cellular factors involved in chikungunya virus infection.
4. Construction of norovirus virus-like particle and development of ELISA system.
5. Epidemiological studies on water-borne viral infections in Thailand.
6. HIV-1 drug resistance test by using ultra deep sequencing.

Papers published in 2013

1. Characterization of self-assembled virus-like particles of ferret hepatitis E virus generated by recombinant baculoviruses.

   Tingting Yang, Michiyo Kataoka, Yasushi Ami, Yuriko Suzaki, Noriko Kishida, Masayuki Shirakura, Masaki Imai, Hideki Asanuma, Naokazu Takeda, Takaji Wakita and Tian-Cheng Li

   J Gen Virol, 94 (Pt 12), 2647-2656, 2013.
2. Chikungunya virus induces a more moderate cytopathic effect in mosquito cells than in mammalian cells.

   Yong-Gang Li, Uamporn Siripanyaphinyo, Uranan Tumkosit, Nitchakarn Noranate, Atchareeya A-nuegoonpipat, Ran Tao, Takeshi Kurosu, Kazuyoshi Ikuta, Naokazu Takeda and Surapee Anantapreecha

   Intervirology, 56 (1), 6-12, 2013.
3. Asian musk shrew as a reservoir of rat hepatitis E virus, China.

   Dawei Guan, Wei Li, Juan Su, Ling Fang, Naokazu Takeda, Takaji Wakita, Tian-Cheng Li and Changwen Ke

   Emerg Infect Dis, 19 (8), 1341-1343, 2013.
4. CCR6 functions as a new coreceptor for limited primary human and simian immunodeficiency viruses.

   Salequl Islam, Nobuaki Shimizu, Sheikh Ariful Hoque, Atsushi Jinno-Oue, Atsushi Tanaka and Hiroo Hoshino

   PLoS One, 8 (8), e73116, 2013.
5. High prevalence of rat hepatitis E virus in wild rats in China.

   Wei Li, Dawei Guan, Juan Su, Naokazu Takeda, Takaji Wakita, Tian-Cheng Li and Chang Wen Ke

   Vet Microbiol, 165 (3-4), 275-280, 2013.
6. No evidence for hepatitis E virus genotype 3 susceptibility in rats.

   Tian-Cheng Li, Yasushi Ami, Yuriko Suzaki, Naokazu Takeda and Wakita Takaji

   Emerg Infect Dis, 19 (8), 1343-1345, 2013.
7. Development of a pseudotyped-lentiviral-vector-based neutralization assay for chikungunya virus infection.

   Natsuko Kishishita, Naokazu Takeda, Atchareeya Anuegoonpipat and Surapee Anantapreecha

   J Clin Microbiol, 51 (5), 1389-1395, 2013.
8. Inhibitory effect of chondroitin sulfate type E on the binding step of human T-cell leukemia virus type 1.

   Atsushi Jinno-Oue, Atsushi Tanaka, Nobuaki Shimizu, Takahisa Mori, Nobuo Sugiura, Koji Kimata, Hiroki Isomura and Hiroo Hoshino

   AIDS Res Hum Retroviruses, 29 (3), 621-629, 2013.
9. Susceptibility of laboratory rats against genotypes 1, 3, 4, and rat hepatitis E viruses.

   Tian-Cheng Li, Sayaka Yoshizaki, Yasushi Ami, Yuriko Suzaki, Shumpei P Yasuda, Kumiko Yoshimatsu, Jiro Arikawa, Naokazu Takeda and Takaji Wakita

   Vet Microbiol, 163 (1-2), 54-61, 2013.
10. X4-Tropic Human Immunodeficiency Virus (HIV), IIIB Utilizes CXCR4 As Coreceptor Distinctly From R5 × 4-Tropic Viruses.

    Salequl Islam, Sheikh Ariful Hoque, Nihad Adnan, Atsushi Tanaka, Atsushi Jinno-Oue and Hiroo Hoshino

    Microbiol Immunol, , , 2013.
11. A novel therapeutic molecule against HTLV-1 infection targeting provirus.

    A Tanaka, S Takeda, R Kariya, K Matsuda, E Urano, S Okada and J Komano

    Leukemia, 27 (8), 1621-1627, 2013.
12. Characterization of full genome of rat hepatitis E virus strain from Vietnam.

    Tian-Cheng Li, Yasushi Ami, Yuriko Suzaki, Shumpei P Yasuda, Kumiko Yoshimatsu, Jiro Arikawa, Naokazu Takeda and Wakita Takaji

    Emerg Infect Dis, 19 (1), 115-118, 2013.
13. CRF01_AE-specific neutralizing activity observed in plasma derived from HIV-1-infected Thai patients residing in northern Thailand: comparison of neutralizing breadth and potency between plasma derived from rapid and slow progressors.

    Sompong Sapsutthipas, Naho Tsuchiya, Panita Pathipavanich, Koya Ariyoshi, Pathom Sawanpanyalert, Naokazu Takeda, Panasda Isarangkura-na-ayuthaya and Masanori Kameoka

    PLoS One, 8 (1), e53920, 2013.

Link

http://www.biken.osaka-u.ac.jp/