Department of Oncogene Research

Staff:

Professor

Masato Okada, Ph.D.

Associate Professor

Shigeyuki Nada, Ph.D.

Chitose Oneyama, Ph.D.

Specially Appointed Researcher

Kentaro Kajiwara, Ph.D.

Kyoko Kakumoto, Ph.D.

Graduate Student

Shunsuke Mori, M.Sc.

Rei Asai, M.Sc.

Yu Komiya, M.Sc.

Ayaka Kitamura

Suguru Nomimura

Ip Chi Yeung

Rie Kokuda

Yuichi Ninomiya

Atsushi Kuwahara

Jun Nakayama

Mari Nada

Lee Le Shi

Undergraduate Student

Akiko Nakayama

Keisuke Kitano

Kentaro Tanaka

Subjects:

1. Functions of the Src family tyrosine kinases (SFK).
2. Molecular mechanisms of SFK-mediated cell transformation.
3. Regulation of tumor growth via the endosomal compartments.

Papers published in 2013

1. MiR-424/503-mediated Rictor upregulation promotes tumor progression.

   Chitose Oneyama, Yoriko Kito, Rei Asai, Jun-ichiro Ikeda, Takuya Yoshida, Daisuke Okuzaki, Rie Kokuda, Kyoko Kakumoto, Ken-ichi Takayama, Satoshi Inoue, Eiichi Morii and Masato Okada

   PLoS One, 8 (11), e80300, 2013.
2. Metabolic Labeling of Yeast Sphingolipids with Radioactive D-erythro-[4,5-3H]dihydrosphingosine.

   Karashima, Kajiwara and Funato

   Bio protocol, , , 2013.
3. The lysosomal signaling anchor p18/LAMTOR1 controls epidermal development by regulating lysosome-mediated catabolic processes.

   Taeko Soma-Nagae, Shigeyuki Nada, Mari Kitagawa, Yusuke Takahashi, Shunsuke Mori, Chitose Oneyama and Masato Okada

   J Cell Sci, 126 (Pt 16), 3575-3584, 2013.
4. Identification of a new interaction mode between the Src homology 2 domain of C-terminal Src kinase (Csk) and Csk-binding protein/phosphoprotein associated with glycosphingolipid microdomains.

   Hiroaki Tanaka, Ken-ichi Akagi, Chitose Oneyama, Masakazu Tanaka, Yuichi Sasaki, Takashi Kanou, Young-Ho Lee, Daisuke Yokogawa, Marc-Werner Dobenecker, Atsushi Nakagawa, Masato Okada and Takahisa Ikegami

   J Biol Chem, 288 (21), 15240-15254, 2013.
5. Involvement of gangliosides in the process of Cbp/PAG phosphorylation by Lyn in developing cerebellar growth cones.

   Naoko Sekino-Suzuki, Kohei Yuyama, Toshiaki Miki, Mizuho Kaneda, Hidenori Suzuki, Naomasa Yamamoto, Tadashi Yamamoto, Chitose Oneyama, Masato Okada and Kohji Kasahara

   J Neurochem, 124 (4), 514-522, 2013.

Link

http://www.biken.osaka-u.ac.jp/