Laboratory of Genomic Research on Pathogenic Bacteria

Staff:

Specially Appointed Professor

Tetsuya Iida, Ph.D.

Specially Appointed Assistant Professor

Shigeaki Matsuda, Ph.D.

Specially Appointed Researcher

Hirotaka Hiyoshi, Ph.D.

Graduate Student

Ryu Okada

Subjects:

1. Characterization of the mechanism(s) used by bacterial pathogens to infect host organisms by identifying infection-related changes in pathogen genome expression.
2. Analysis of the mechanism(s) that lead to the emergence of new infectious diseases.
3. Investigation of the life cycles of bacterial pathogens in their natural environments.
4. Development of new methods for the rapid identification of bacterial pathogens based on genome information.

Papers published in 2013

1. Sinkhole-like structures as bioproductivity hotspots in the Abrolhos Bank

   Cavalcanti, Gregoracci, Longo, Bastos, Ferreira, Francini, Cavalcanti, Ghisolfi, Kruger, Guth, Sumida, Bruce, Maia-Neto, Santos, Iida, Moura, Amado and Thompson

   Continental Shelf Research, 70, 126-134, 2013.
2. Characterization of all RND-type multidrug efflux transporters in Vibrio parahaemolyticus.

   Taira Matsuo, Koji Nakamura, Toshio Kodama, Taro Mikami, Hirotaka Hiyoshi, Tomofusa Tsuchiya, Wakano Ogawa and Teruo Kuroda

   Microbiologyopen, 2 (5), 725-742, 2013.
3. Horizontal gene transfer of a genetic island encoding a type III secretion system distributed in Vibrio cholerae.

   Masatomo Morita, Shouji Yamamoto, Hirotaka Hiyoshi, Toshio Kodama, Masatoshi Okura, Eiji Arakawa, Munirul Alam, Makoto Ohnishi, Hidemasa Izumiya and Haruo Watanabe

   Microbiol Immunol, 57 (5), 334-339, 2013.
4. Fatal sepsis caused by an unusual Klebsiella species that was misidentified by an automated identification system.

   Masafumi Seki, Kazuyoshi Gotoh, Shota Nakamura, Yukihiro Akeda, Tadashi Yoshii, Shinichi Miyaguchi, Hidenori Inohara, Toshihiro Horii, Kazunori Oishi, Tetsuya Iida and Kazunori Tomono

   J Med Microbiol, 62 (Pt 5), 801-803, 2013.
5. Metagenomic analysis of healthy and white plague-affected Mussismilia braziliensis corals.

   Gizele D Garcia, Gustavo B Gregoracci, Eidy de O Santos, Pedro M Meirelles, Genivaldo G Z Silva, Rob Edwards, Tomoo Sawabe, Kazuyoshi Gotoh, Shota Nakamura, Tetsuya Iida, Rodrigo L de Moura and Fabiano L Thompson

   Microb Ecol, 65 (4), 1076-1086, 2013.
6. Metagenomic profile of gut microbiota in children during cholera and recovery.

   Shirajum Monira, Shota Nakamura, Kazuyoshi Gotoh, Kaori Izutsu, Haruo Watanabe, Nur Haque Alam, Takaaki Nakaya, Toshihiro Horii, Sk Imran Ali, Tetsuya Iida and Munirul Alam

   Gut Pathog, 5 (1), 1, 2013.
7. Vibrio parahaemolyticus effector proteins suppress inflammasome activation by interfering with host autophagy signaling.

   Naomi Higa, Claudia Toma, Yukiko Koizumi, Noboru Nakasone, Toshitsugu Nohara, Junya Masumoto, Toshio Kodama, Tetsuya Iida and Toshihiko Suzuki

   PLoS Pathog, 9 (1), e1003142, 2013.

Link

http://www.biken.osaka-u.ac.jp/