Laboratory of Combined Research on Microbiology and Immunology

Staff:

Associate Professor

Hiroki Nagai, Ph.D.

Specially Appointed Associate Professor

Tomoko Kubori, Ph.D.

Specially Appointed Researcher

Andree M. Hubber, Ph.D.

Xuan Thanh Bui, Ph.D.

Subjects:

1. Structural analysis of effector transport machinery
2. Molecular analysis of mammalian host manipulation by Legionella sp.
3. Molecular analysis of natural host manipulation by Legionella sp.

Papers published in 2013

1. Modulation of the ubiquitination machinery by Legionella.

   Andree Hubber, Tomoko Kubori and Hiroki Nagai

   Curr Top Microbiol Immunol, 376, 227-247, 2013.
2. Identification and functional characterization of K(+) transporters encoded by Legionella pneumophila kup genes.

   Juliana I Hori, Marcelo S F Pereira, Craig R Roy, Hiroki Nagai and Dario S Zamboni

   Cell Microbiol, 15 (12), 2006-2019, 2013.
3. Protochlamydia induces apoptosis of human HEp-2 cells through mitochondrial dysfunction mediated by chlamydial protease-like activity factor.

   Junji Matsuo, Shinji Nakamura, Atsushi Ito, Tomohiro Yamazaki, Kasumi Ishida, Yasuhiro Hayashi, Mitsutaka Yoshida, Kaori Takahashi, Tsuyoshi Sekizuka, Fumihiko Takeuchi, Makoto Kuroda, Hiroki Nagai, Kyoko Hayashida, Chihiro Sugimoto and Hiroyuki Yamaguchi

   PLoS One, 8 (2), e56005, 2013.
4. Purification and characterization of legionella U-box-type E3 ubiquitin ligase.

   Hiroki Nagai and Tomoko Kubori

   Methods Mol Biol, 954, 347-354, 2013.

Link

http://www.biken.osaka-u.ac.jp/