Department of Viral Infections

Subjects:

1. Analysis of host genetic factors affecting disease courses of human immunodeficiency virus (HIV) infection.
2. Studies on chemokines and chemokine receptors.
3. Analysis of molecular mechanisms of HIV entry into target cells.
4. Analysis of molecular mechanisms of HIV virion formation.
5. Development of a novel vector system based on Sendai virus.

Papers published in 2012

1. Elicitation of Both Anti HIV-1 Env Humoral and Cellular Immunities by Replicating Vaccinia Prime Sendai Virus Boost Regimen and Boosting by CD40Lm.

   Xianfeng Zhang, Tomoyoshi Sobue, Mao Isshiki, Shun-Ichi Makino, Makoto Inoue, Kazunori Kato, Tatsuo Shioda, Takashi Ohashi, Hirotaka Sato, Jun Komano, Hideji Hanabusa and Hisatoshi Shida

   PLoS One, 7 (12), e51633, 2012.
2. The Carboxyl-Terminus of Human Immunodeficiency Virus Type 2 Circulating Recombinant form 01_AB Capsid Protein Affects Sensitivity to Human TRIM5α.

   Tadashi Miyamoto, Emi E Nakayama, Masaru Yokoyama, Shiro Ibe, Shunpei Takehara, Ken Kono, Yoshiyuki Yokomaku, Massimo Pizzato, Jeremy Luban, Wataru Sugiura, Hironori Sato and Tatsuo Shioda

   PLoS One, 7 (10), e47757, 2012.
3. Influence of ABCB-1 C3435T polymorphisms on plasma nevirapine and efavirenz levels and their effects on virologic and immunological outcomes in HIV/TB co-infected Thai adults under anti-retroviral therapy.

   Sumonmal Uttayamakul, Sirirat Likanonsakul, Weerawat Manosuthi, Nuanjun Wichukchinda, Tatsuo Shioda and Srisin Khusmith

   Southeast Asian J Trop Med Public Health, 43 (1), 78-88, 2012.
4. Allele frequency of antiretroviral host factor TRIMCyp in wild-caught cynomolgus macaques (Macaca fascicularis).

   Akatsuki Saito, Yoshi Kawamoto, Atsunori Higashino, Tomoyuki Yoshida, Tomoko Ikoma, Yuriko Suzaki, Yasushi Ami, Tatsuo Shioda, Emi E Nakayama and Hirofumi Akari

   Front Microbiol, 3, 314, 2012.
5. Electrostatic potential of human immunodeficiency virus type 2 and rhesus macaque simian immunodeficiency virus capsid proteins.

   Katarzyna Bozek, Emi E Nakayama, Ken Kono and Tatsuo Shioda

   Front Microbiol, 3, 206, 2012.
6. Role of Human TRIM5α in Intrinsic Immunity.

   Emi E Nakayama and Tatsuo Shioda

   Front Microbiol, 3, 97, 2012.
7. A proposal for a new HIV-1 DLS structural model.

   Jun-Ichi Sakuragi, Hirotaka Ode, Sayuri Sakuragi, Tatsuo Shioda and Hironori Sato

   Nucleic Acids Res, 40 (11), 5012-5022, 2012.
8. TRIM5α and Species Tropism of HIV/SIV.

   Emi E Nakayama and Tatsuo Shioda

   Front Microbiol, 3, 13, 2012.
9. Geographic, Genetic and functional diversity of antiretroviral host factor TRIMCyp in cynomolgus macaque (Macaca fascicularis).

   Akatuski Saito, Ken Kono, Masako Nomaguchi, Yasuhiro Yasutomi, Akio Adachi, Tatsuo Shioda, Hirofumi Akari and Emi E Nakayama

   J Gen Virol, 93 (Pt.3), 594-602, 2012.

Link

http://www.biken.osaka-u.ac.jp/