Department of Molecular Immunology

Subjects:

1. Molecular mechanisms involved in regulation of immune responses.
2. Mechanism of development of autoimmune diseases.
3. Molecular mechanism by which Epstein-Barr virus (EBV) causes B cell growth transformation and the modification of the differentiation.

Papers published in 2012

1. Protein kinase N1, a cell inhibitor of Akt kinase, has a central role in quality control of germinal center formation.

   Teruhito Yasui, Kaori Sakakibara-Yada, Taki Nishimura, Kentaro Morita, Satoru Tada, George Mosialos, Elliott Kieff and Hitoshi Kikutani

   Proc Natl Acad Sci U S A, 109 (51), 21022-21027, 2012.
2. The CD100 receptor interacts with its plexin B2 ligand to regulate epidermal γδ T cell function.

   Deborah A Witherden, Megumi Watanabe, Olivia Garijo, Stephanie E Rieder, Gor Sarkisyan, Shane J F Cronin, Petra Verdino, Ian A Wilson, Atsushi Kumanogoh, Hitoshi Kikutani, Luc Teyton, Wolfgang H Fischer and Wendy L Havran

   Immunity, 37 (2), 314-325, 2012.

Link

http://www.biken.osaka-u.ac.jp/