Department of Molecular Virology

Subjects:

1. Studies on Hepatitis C virus.
2. Development of viral vectors.

Published Papers

1. Cochaperone activity of human butyrate-induced transcript 1 facilitates hepatitis C virus replication through an Hsp90-dependent pathway.

   Shuhei Taguwa, Hiroto Kambara, Hiroko Omori, Hideki Tani, Takayuki Abe, Yoshio Mori, Tetsuro Suzuki, Tamotsu Yoshimori, Kohji Moriishi and Yoshiharu Matsuura

   J Virol, 83 (20), 10427-10436, 2009.
2. Biological and immunological characteristics of hepatitis E virus-like particles based on the crystal structure.

   Tetsuo Yamashita, Yoshio Mori, Naoyuki Miyazaki, R Holland Cheng, Masato Yoshimura, Hideaki Unno, Ryoichi Shima, Kohji Moriishi, Tomitake Tsukihara, Tian Cheng Li, Naokazu Takeda, Tatsuo Miyamura and Yoshiharu Matsuura

   Proc Natl Acad Sci U S A, 106 (31), 12986-12991, 2009.
3. Human VAP-C negatively regulates hepatitis C virus propagation.

   Hiroshi Kukihara, Kohji Moriishi, Shuhei Taguwa, Hideki Tani, Takayuki Abe, Yoshio Mori, Tetsuro Suzuki, Takasuke Fukuhara, Akinobu Taketomi, Yoshihiko Maehara and Yoshiharu Matsuura

   J Virol, 83 (16), 7959-7969, 2009.
4. Baculovirus induces type I IFN production through TLR-dependent and -independent pathways in a cell type-specific manner.

   Takayuki Abe, Yuuki Kaname, Xiauyu Wen, Hideki Tani, Kohji Moriishi, Satoshi Uematsu, Osamu Takeuchi, Ken J Ishii, Taro Kawai, Shizuo Akira and Yoshiharu Matsuura

   J Virol, 83 (15), 7629-7640, 2009.
5. Involvement of creatine kinase B in hepatitis C virus genome replication through interaction with the viral NS4A protein.

   Hiromichi Hara, Hideki Aizaki, Mami Matsuda, Fumiko Shinkai-Ouchi, Yasushi Inoue, Kyoko Murakami, Ikuo Shoji, Hayato Kawakami, Yoshiharu Matsuura, Michael M C Lai, Tatsuo Miyamura, Takaji Wakita and Tetsuro Suzuki

   J Virol, 83 (10), 5137-5147, 2009.
6. Proteasomal turnover of hepatitis C virus core protein is regulated by two distinct mechanisms: ubiquitin-dependent and ubiquitin-independent but PA28γ-dependent.

   Ryosuke Suzuki, Kohji Moriishi, Kouichirou Fukuda, Masayuki Shirakura, Koji Ishii, Ikuo Shoji, Takaji Wakita, Tatsuo Miyamura, Yoshiharu Matsuura and Tetsuro Suzuki

   J Virol, 83 (5), 2389-2392, 2009.
7. Tacrolimus ameliorates metabolic disturbance and oxidative stress caused by hepatitis C virus core protein: analysis using mouse model and cultured cells.

   Kyoji Moriya, Hideyuki Miyoshi, Takeya Tsutsumi, Seiko Shinzawa, Hajime Fujie, Yoshizumi Shintani, Hiroshi Yotsuyanagi, Kohji Moriishi, Yoshiharu Matsuura, Tetsuro Suzuki, Tatsuo Miyamura and Kazuhiko Koike

   Am J Pathol, 175 (4), 1515-1524, 2009.
8. Rho-kinase contributes to sustained RhoA activation through phosphorylation of p190A RhoGAP.

   Kazutaka Mori, Mutsuki Amano, Mikito Takefuji, Katsuhiro Kato, Yasuhiro Morita, Tomoki Nishioka, Yoshiharu Matsuura, Toyoaki Murohara and Kozo Kaibuchi

   J Biol Chem, 284 (8), 5067-5076, 2009.
9. Mobile DHHC palmitoylating enzyme mediates activity-sensitive synaptic targeting of PSD-95.

   Jun Noritake, Yuko Fukata, Tsuyoshi Iwanaga, Naoki Hosomi, Ryouhei Tsutsumi, Naoto Matsuda, Hideki Tani, Hiroko Iwanari, Yasuhiro Mochizuki, Tatsuhiko Kodama, Yoshiharu Matsuura, David S Bredt, Takao Hamakubo and Masaki Fukata

   J Cell Biol, 186 (1), 147-160, 2009.

Link

http://www.biken.osaka-u.ac.jp/