Laboratory for Infection Cell Biology

Subject:

1. Studies on the transport mechanisms of the botulinum neurotoxin complex.

Published Papers

1. Disruption of the epithelial barrier by botulinum haemagglutinin (HA) proteins - differences in cell tropism and the mechanism of action between HA proteins of types A or B, and HA proteins of type C.

   Yingji Jin, Yuki Takegahara, Yo Sugawara, Takuhiro Matsumura and Yukako Fujinaga

   Microbiology, 155 (Pt 1), 35-45, 2009.
2. A novel function of botulinum toxin-associated proteins: HA proteins disrupt intestinal epithelial barrier to increase toxin absorption.

   Y Fujinaga, T Matsumura, Y Jin, Y Takegahara and Y Sugawara

   Toxicon, 54 (5), 583-586, 2009.

Link

http://www.biken.osaka-u.ac.jp/