Laboratory of Malariology

Department of Infectious Diseases Control;

Subjects:

1. Population genetics of malaria parasites.
2. The evolution of antigen polymorphism in malaria parasites.
3. Co-evolution between malaria parasites and hosts.
4. The evolution of the mitochondrial genome of Apicomplexa.
5. Comparative genomics of Plasmodium vivax and related simian parasites.
6. Simulation of malaria drug resistance using mutator parasites.

Published Papers

1. Failure to detect Plasmodium vivax in West and Central Africa by PCR species typing.

   Richard L Culleton, Toshihiro Mita, Mathieu Ndounga, Holger Unger, Pedro V L Cravo, Giacomo M Paganotti, Nobuyuki Takahashi, Akira Kaneko, Hideaki Eto, Halidou Tinto, Corine Karema, Umberto D'Alessandro, Virgilio do Rosário, Takatoshi Kobayakawa, Francine Ntoumi, Richard Carter and Kazuyuki Tanabe

   Malar J, 7, 174, 2008.
2. Big bang in the evolution of extant malaria parasites.

   Toshiyuki Hayakawa, Richard Culleton, Hiroto Otani, Toshihiro Horii and Kazuyuki Tanabe

   Mol Biol Evol, 25 (10), 2233-2239, 2008.
3. Genetic evidence for Plasmodium falciparum resistance to chloroquine and pyrimethamine in Indochina and the Western Pacific between 1984 and 1998.

   Yumiko Saito-Nakano, Kazuyuki Tanabe, Kiseko Kamei, Moritoshi Iwagami, Kanako Komaki-Yasuda, Shin-ichiro Kawazu, Shigeyuki Kano, Hiroshi Ohmae and Takuro Endo

   Am J Trop Med Hyg, 79 (4), 613-619, 2008.
4. Evolution and phylogeny of the heterogeneous cytosolic SSU rRNA genes in the genus Plasmodium.

   Yuriko Nishimoto, Nobuko Arisue, Satoru Kawai, Ananias A Escalante, Toshihiro Horii, Kazuyuki Tanabe and Tetsuo Hashimoto

   Mol Phylogenet Evol, 47 (1), 45-53, 2008.
5. Diversity and evolution of the rhoph1/clag multigene family of Plasmodium falciparum.

   Hideyuki Iriko, Osamu Kaneko, Hitoshi Otsuki, Takafumi Tsuboi, Xin-Zhuan Su, Kazuyuki Tanabe and Motomi Torii

   Mol Biochem Parasitol, 158 (1), 11-21, 2008.
6. Biological implication for loss of function at major histocompatibility complex loci.

   Hiromi Sawai, Yasuhiro Go and Yoko Satta

   Immunogenetics, 60 (6), 295-302, 2008.
7. A case of toxic epidermal necrolysis-like dermatitis evolving from contact dermatitis of the hands associated with exposure to dendrimers.

   T Toyama, H Matsuda, I Ishida, M Tani, S Kitaba, S Sano and I Katayama

   Contact Dermatitis, 59 (2), 122-123, 2008.
8. Relationship between DNA methylation states and transcription of individual isoforms encoded by the protocadherin-alpha gene cluster.

   Masahumi Kawaguchi, Tomoko Toyama, Ryosuke Kaneko, Teruyoshi Hirayama, Yoshimi Kawamura and Takeshi Yagi

   J Biol Chem, 283 (18), 12064-12075, 2008.
9. Regulation of gonad development and respiratory metabolism associated with food availability and reproductive diapause in the rice bug Leptocorisa chinensis.

   Shin-Ichiro Tachibana and Tomonari Watanabe

   J Insect Physiol, 54 (2), 445-453, 2008.
10. Sensitive stages for photoperiodic induction of pupal diapause in the flesh fly Sarcophaga similis (Meade) (Deptera: Sarcophagidae).

    Masako Tanaka, Shin-Ichiro Tachibana and Hideharu Numata

    Appl Entomol Zool, 43 (3), 403-407, 2008.

Link

http://www.biken.osaka-u.ac.jp/